Incident cardiovascular disease events over the FINGER follow-up adjusted for age, education, sex, APOE ɛ4 status, study site, and antihypertensive medication
| . | Intervention (n = 631) . | Control (n = 628) . | Intervention vs. controla . | ||||
|---|---|---|---|---|---|---|---|
| No events (%) . | Time (py) . | No events (%) . | Time (py) . | HR . | 95% CI . | P-value . | |
| Coronary event | 48 (7.6) | 4901 | 51 (8.1) | 4830 | 0.84 | (0.56–1.26) | 0.396 |
| Stroke | 48 (7.6) | 4885 | 57 (9.1) | 4866 | 0.80 | (0.54–1.18) | 0.264 |
| TIA | 27 (4.3) | 4981 | 41 (6.5) | 4888 | 0.63 | (0.38–1.03) | 0.064 |
| Stroke and TIA | 66 (10.5) | 4819 | 87 (13.9) | 4758 | 0.71 | (0.51–0.99) | 0.043 |
| Total CVD events (coronary events, stroke, and TIA) | 107 (17.0) | 4667 | 122 (19.4) | 4608 | 0.80 | (0.61–1.04) | 0.098 |
| . | Intervention (n = 631) . | Control (n = 628) . | Intervention vs. controla . | ||||
|---|---|---|---|---|---|---|---|
| No events (%) . | Time (py) . | No events (%) . | Time (py) . | HR . | 95% CI . | P-value . | |
| Coronary event | 48 (7.6) | 4901 | 51 (8.1) | 4830 | 0.84 | (0.56–1.26) | 0.396 |
| Stroke | 48 (7.6) | 4885 | 57 (9.1) | 4866 | 0.80 | (0.54–1.18) | 0.264 |
| TIA | 27 (4.3) | 4981 | 41 (6.5) | 4888 | 0.63 | (0.38–1.03) | 0.064 |
| Stroke and TIA | 66 (10.5) | 4819 | 87 (13.9) | 4758 | 0.71 | (0.51–0.99) | 0.043 |
| Total CVD events (coronary events, stroke, and TIA) | 107 (17.0) | 4667 | 122 (19.4) | 4608 | 0.80 | (0.61–1.04) | 0.098 |
HR, hazard ratio; CI, confidence interval; py, person years; CVD, cardiovascular disease; TIA, transient ischaemic attack.
Models adjusted for age, education, sex, APOE ɛ4 status, study site, and blood pressure medication at baseline. Unadjusted models presented in Supplementary material online, Table S5.
Incident cardiovascular disease events over the FINGER follow-up adjusted for age, education, sex, APOE ɛ4 status, study site, and antihypertensive medication
| . | Intervention (n = 631) . | Control (n = 628) . | Intervention vs. controla . | ||||
|---|---|---|---|---|---|---|---|
| No events (%) . | Time (py) . | No events (%) . | Time (py) . | HR . | 95% CI . | P-value . | |
| Coronary event | 48 (7.6) | 4901 | 51 (8.1) | 4830 | 0.84 | (0.56–1.26) | 0.396 |
| Stroke | 48 (7.6) | 4885 | 57 (9.1) | 4866 | 0.80 | (0.54–1.18) | 0.264 |
| TIA | 27 (4.3) | 4981 | 41 (6.5) | 4888 | 0.63 | (0.38–1.03) | 0.064 |
| Stroke and TIA | 66 (10.5) | 4819 | 87 (13.9) | 4758 | 0.71 | (0.51–0.99) | 0.043 |
| Total CVD events (coronary events, stroke, and TIA) | 107 (17.0) | 4667 | 122 (19.4) | 4608 | 0.80 | (0.61–1.04) | 0.098 |
| . | Intervention (n = 631) . | Control (n = 628) . | Intervention vs. controla . | ||||
|---|---|---|---|---|---|---|---|
| No events (%) . | Time (py) . | No events (%) . | Time (py) . | HR . | 95% CI . | P-value . | |
| Coronary event | 48 (7.6) | 4901 | 51 (8.1) | 4830 | 0.84 | (0.56–1.26) | 0.396 |
| Stroke | 48 (7.6) | 4885 | 57 (9.1) | 4866 | 0.80 | (0.54–1.18) | 0.264 |
| TIA | 27 (4.3) | 4981 | 41 (6.5) | 4888 | 0.63 | (0.38–1.03) | 0.064 |
| Stroke and TIA | 66 (10.5) | 4819 | 87 (13.9) | 4758 | 0.71 | (0.51–0.99) | 0.043 |
| Total CVD events (coronary events, stroke, and TIA) | 107 (17.0) | 4667 | 122 (19.4) | 4608 | 0.80 | (0.61–1.04) | 0.098 |
HR, hazard ratio; CI, confidence interval; py, person years; CVD, cardiovascular disease; TIA, transient ischaemic attack.
Models adjusted for age, education, sex, APOE ɛ4 status, study site, and blood pressure medication at baseline. Unadjusted models presented in Supplementary material online, Table S5.
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