| Variable . | Baseline . | Patients with peak hs-cTnI >500× URL . | Patients with peak hs-cTnI <500×URL . | P-value* (two-sided) . |
|---|---|---|---|---|
| Patients, n (%) | 4684 (100) | 387 (8.3) | 4297 (91.7) | |
| Age (years), mean (±SD) | 67.39 (±9.71) | 68.76 (±10.03) | 67.26 (±9.67) | 0.005 |
| BMI (kg/m2), mean (±SD) | 28.56 (±4.61) | 27.77 (±4.31) | 28.63 (±4.63) | <0.001 |
| Female sex, n (%) | 909 (19.4) | 94 (24.29) | 815 (19) | <0.001 |
| Angina Severity CCS Class, median (IQR) | 1.0 (2.0) | 1.0 (1.0) | 1.0 (2.0) | 0.196 |
| Creatinine (mg/dL), mean (±SD) | 1.12 (±0.70) | 1.19 (±0.77) | 1.11 (±0.69) | 0.055 |
| eGFR (mL/min/1.73 m2), median (IQR) | 75 (28) | 70 (31) | 76 (28) | <0.001 |
| Haemoglobin (g/dL), median (IQR) | 14.3 (2) | 14.1 (2.1) | 14.3 (2) | 0.061 |
| LDL (mg/dL), mean (±SD) | 111.08 (±42) | 115.28 (±43.59) | 110.70 (±41.86) | 0.12 |
| HbA1c (%), median (IQR) | 5.8 (1.2) | 5.8 (1.1) | 5.8 (1.2) | 0.55 |
| EuroSCORE II, median (IQR) | 1.26 (1.36) | 1.53 (2.19) | 1.25 (1.31) | <0.001 |
| LVEF baseline (%), median (IQR) | 58 (13) | 57 (12) | 58 (13) | 0.69 |
| COPD, n (%) | 228 (4.84) | 12 (3.1) | 216 (5.03) | <0.001 |
| History of AF, n (%) | 2 30 (4.91) | 28 (7.23) | 202 (4.71) | <0.001 |
| Prior cardiac surgery, n (%) | 177 (3.78) | 33 (8.53) | 144 (3.36) | <0.001 |
| Arterial hypertension, n (%) | 4160 (88.81) | 350 (90.44) | 3803 (88.65) | <0.001 |
| Diabetes, n (%) | 1739 (37.13) | 142 (36.69) | 1593 (37.13) | <0.001 |
| PAD, n (%) | 581 (12.40) | 60 (15.50) | 520 (12.12) | <0.001 |
| Smoking, n (%) | 2012 (42.96) | 162 (41.86) | 1846 (43.04) | <0.001 |
| Prior stroke, n (%) | 161 (3.44) | 12 (3.1) | 149 (3.47) | <0.001 |
| Chronic dialysis, n (%) | 65 (1.39) | 8 (2.07) | 57 (1.33) | <0.001 |
| History of PCI, n (%) | 1448 (30.91) | 126 (32.56) | 1319 (30.75) | 0.01 |
| History of MI, n (%) | 1016 (21.69) | 88 (22.74) | 927 (21.61) | <0.001 |
| CPB use, n (%) | 692 (14.77) | 128 (33.07) | 564 (13.15) | <0.001 |
| Time on CBP (min), median (IQR) | 84.5 (38) | 91 (51) | 84 (36) | 0.33 |
| Aortic cross-clamp time (min), median (IQR) | 62 (28) | 70 (38.75) | 61 (28) | 0.03 |
| Duration of procedure (min), median (IQR) | 198 (64) | 226 (84.5) | 196 (64) | <0.001 |
| LIMA bypass, n (%) | 4418 (94.32) | 348 (89.92) | 4063 (94.71) | <0.001 |
| Total arterial bypasses, n (%) | 1199 (25.60) | 73 (18.86) | 1125 (26.22) | <0.001 |
| Length of ICU stay (h), median (IQR) | 23 (26) | 47 (89.75) | 22 (22) | <0.001 |
| Duration on ventilator (h), median (IQR) | 7.98 (4.66) | 10.36 (11.85) | 7.83 (4.34) | <0.001 |
| Length of hospitalization (days), median (IQR) | 12 (3) | 13 (5.5) | 12 (13) | <0.001 |
| Variable . | Baseline . | Patients with peak hs-cTnI >500× URL . | Patients with peak hs-cTnI <500×URL . | P-value* (two-sided) . |
|---|---|---|---|---|
| Patients, n (%) | 4684 (100) | 387 (8.3) | 4297 (91.7) | |
| Age (years), mean (±SD) | 67.39 (±9.71) | 68.76 (±10.03) | 67.26 (±9.67) | 0.005 |
| BMI (kg/m2), mean (±SD) | 28.56 (±4.61) | 27.77 (±4.31) | 28.63 (±4.63) | <0.001 |
| Female sex, n (%) | 909 (19.4) | 94 (24.29) | 815 (19) | <0.001 |
| Angina Severity CCS Class, median (IQR) | 1.0 (2.0) | 1.0 (1.0) | 1.0 (2.0) | 0.196 |
| Creatinine (mg/dL), mean (±SD) | 1.12 (±0.70) | 1.19 (±0.77) | 1.11 (±0.69) | 0.055 |
| eGFR (mL/min/1.73 m2), median (IQR) | 75 (28) | 70 (31) | 76 (28) | <0.001 |
| Haemoglobin (g/dL), median (IQR) | 14.3 (2) | 14.1 (2.1) | 14.3 (2) | 0.061 |
| LDL (mg/dL), mean (±SD) | 111.08 (±42) | 115.28 (±43.59) | 110.70 (±41.86) | 0.12 |
| HbA1c (%), median (IQR) | 5.8 (1.2) | 5.8 (1.1) | 5.8 (1.2) | 0.55 |
| EuroSCORE II, median (IQR) | 1.26 (1.36) | 1.53 (2.19) | 1.25 (1.31) | <0.001 |
| LVEF baseline (%), median (IQR) | 58 (13) | 57 (12) | 58 (13) | 0.69 |
| COPD, n (%) | 228 (4.84) | 12 (3.1) | 216 (5.03) | <0.001 |
| History of AF, n (%) | 2 30 (4.91) | 28 (7.23) | 202 (4.71) | <0.001 |
| Prior cardiac surgery, n (%) | 177 (3.78) | 33 (8.53) | 144 (3.36) | <0.001 |
| Arterial hypertension, n (%) | 4160 (88.81) | 350 (90.44) | 3803 (88.65) | <0.001 |
| Diabetes, n (%) | 1739 (37.13) | 142 (36.69) | 1593 (37.13) | <0.001 |
| PAD, n (%) | 581 (12.40) | 60 (15.50) | 520 (12.12) | <0.001 |
| Smoking, n (%) | 2012 (42.96) | 162 (41.86) | 1846 (43.04) | <0.001 |
| Prior stroke, n (%) | 161 (3.44) | 12 (3.1) | 149 (3.47) | <0.001 |
| Chronic dialysis, n (%) | 65 (1.39) | 8 (2.07) | 57 (1.33) | <0.001 |
| History of PCI, n (%) | 1448 (30.91) | 126 (32.56) | 1319 (30.75) | 0.01 |
| History of MI, n (%) | 1016 (21.69) | 88 (22.74) | 927 (21.61) | <0.001 |
| CPB use, n (%) | 692 (14.77) | 128 (33.07) | 564 (13.15) | <0.001 |
| Time on CBP (min), median (IQR) | 84.5 (38) | 91 (51) | 84 (36) | 0.33 |
| Aortic cross-clamp time (min), median (IQR) | 62 (28) | 70 (38.75) | 61 (28) | 0.03 |
| Duration of procedure (min), median (IQR) | 198 (64) | 226 (84.5) | 196 (64) | <0.001 |
| LIMA bypass, n (%) | 4418 (94.32) | 348 (89.92) | 4063 (94.71) | <0.001 |
| Total arterial bypasses, n (%) | 1199 (25.60) | 73 (18.86) | 1125 (26.22) | <0.001 |
| Length of ICU stay (h), median (IQR) | 23 (26) | 47 (89.75) | 22 (22) | <0.001 |
| Duration on ventilator (h), median (IQR) | 7.98 (4.66) | 10.36 (11.85) | 7.83 (4.34) | <0.001 |
| Length of hospitalization (days), median (IQR) | 12 (3) | 13 (5.5) | 12 (13) | <0.001 |
SD, standard deviation; IQR, interquartile range; BMI, body mass index; CCS, Canadian Cardiovascular Society; eGFR, estimated glomerular filtration rate, according to the Modification of Diet in Renal Disease equation; LDL, low-density lipoprotein; HbA1c, glycated haemoglobin; LVEF, left ventricular ejection fraction; COPD, chronic obstructive pulmonary disease; AF, atrial fibrillation; PAD, peripheral arterial disease; PCI, percutaneous coronary intervention; MI, myocardial infarction; CPB, cardiopulmonary bypass; LIMA, left internal mammary artery; hs-cTnI, high-sensitivity cardiac troponin I; URL, upper reference limit.
P-value for comparing those with peak hs-cTnI > 500×URL versus <500× URL.
| Variable . | Baseline . | Patients with peak hs-cTnI >500× URL . | Patients with peak hs-cTnI <500×URL . | P-value* (two-sided) . |
|---|---|---|---|---|
| Patients, n (%) | 4684 (100) | 387 (8.3) | 4297 (91.7) | |
| Age (years), mean (±SD) | 67.39 (±9.71) | 68.76 (±10.03) | 67.26 (±9.67) | 0.005 |
| BMI (kg/m2), mean (±SD) | 28.56 (±4.61) | 27.77 (±4.31) | 28.63 (±4.63) | <0.001 |
| Female sex, n (%) | 909 (19.4) | 94 (24.29) | 815 (19) | <0.001 |
| Angina Severity CCS Class, median (IQR) | 1.0 (2.0) | 1.0 (1.0) | 1.0 (2.0) | 0.196 |
| Creatinine (mg/dL), mean (±SD) | 1.12 (±0.70) | 1.19 (±0.77) | 1.11 (±0.69) | 0.055 |
| eGFR (mL/min/1.73 m2), median (IQR) | 75 (28) | 70 (31) | 76 (28) | <0.001 |
| Haemoglobin (g/dL), median (IQR) | 14.3 (2) | 14.1 (2.1) | 14.3 (2) | 0.061 |
| LDL (mg/dL), mean (±SD) | 111.08 (±42) | 115.28 (±43.59) | 110.70 (±41.86) | 0.12 |
| HbA1c (%), median (IQR) | 5.8 (1.2) | 5.8 (1.1) | 5.8 (1.2) | 0.55 |
| EuroSCORE II, median (IQR) | 1.26 (1.36) | 1.53 (2.19) | 1.25 (1.31) | <0.001 |
| LVEF baseline (%), median (IQR) | 58 (13) | 57 (12) | 58 (13) | 0.69 |
| COPD, n (%) | 228 (4.84) | 12 (3.1) | 216 (5.03) | <0.001 |
| History of AF, n (%) | 2 30 (4.91) | 28 (7.23) | 202 (4.71) | <0.001 |
| Prior cardiac surgery, n (%) | 177 (3.78) | 33 (8.53) | 144 (3.36) | <0.001 |
| Arterial hypertension, n (%) | 4160 (88.81) | 350 (90.44) | 3803 (88.65) | <0.001 |
| Diabetes, n (%) | 1739 (37.13) | 142 (36.69) | 1593 (37.13) | <0.001 |
| PAD, n (%) | 581 (12.40) | 60 (15.50) | 520 (12.12) | <0.001 |
| Smoking, n (%) | 2012 (42.96) | 162 (41.86) | 1846 (43.04) | <0.001 |
| Prior stroke, n (%) | 161 (3.44) | 12 (3.1) | 149 (3.47) | <0.001 |
| Chronic dialysis, n (%) | 65 (1.39) | 8 (2.07) | 57 (1.33) | <0.001 |
| History of PCI, n (%) | 1448 (30.91) | 126 (32.56) | 1319 (30.75) | 0.01 |
| History of MI, n (%) | 1016 (21.69) | 88 (22.74) | 927 (21.61) | <0.001 |
| CPB use, n (%) | 692 (14.77) | 128 (33.07) | 564 (13.15) | <0.001 |
| Time on CBP (min), median (IQR) | 84.5 (38) | 91 (51) | 84 (36) | 0.33 |
| Aortic cross-clamp time (min), median (IQR) | 62 (28) | 70 (38.75) | 61 (28) | 0.03 |
| Duration of procedure (min), median (IQR) | 198 (64) | 226 (84.5) | 196 (64) | <0.001 |
| LIMA bypass, n (%) | 4418 (94.32) | 348 (89.92) | 4063 (94.71) | <0.001 |
| Total arterial bypasses, n (%) | 1199 (25.60) | 73 (18.86) | 1125 (26.22) | <0.001 |
| Length of ICU stay (h), median (IQR) | 23 (26) | 47 (89.75) | 22 (22) | <0.001 |
| Duration on ventilator (h), median (IQR) | 7.98 (4.66) | 10.36 (11.85) | 7.83 (4.34) | <0.001 |
| Length of hospitalization (days), median (IQR) | 12 (3) | 13 (5.5) | 12 (13) | <0.001 |
| Variable . | Baseline . | Patients with peak hs-cTnI >500× URL . | Patients with peak hs-cTnI <500×URL . | P-value* (two-sided) . |
|---|---|---|---|---|
| Patients, n (%) | 4684 (100) | 387 (8.3) | 4297 (91.7) | |
| Age (years), mean (±SD) | 67.39 (±9.71) | 68.76 (±10.03) | 67.26 (±9.67) | 0.005 |
| BMI (kg/m2), mean (±SD) | 28.56 (±4.61) | 27.77 (±4.31) | 28.63 (±4.63) | <0.001 |
| Female sex, n (%) | 909 (19.4) | 94 (24.29) | 815 (19) | <0.001 |
| Angina Severity CCS Class, median (IQR) | 1.0 (2.0) | 1.0 (1.0) | 1.0 (2.0) | 0.196 |
| Creatinine (mg/dL), mean (±SD) | 1.12 (±0.70) | 1.19 (±0.77) | 1.11 (±0.69) | 0.055 |
| eGFR (mL/min/1.73 m2), median (IQR) | 75 (28) | 70 (31) | 76 (28) | <0.001 |
| Haemoglobin (g/dL), median (IQR) | 14.3 (2) | 14.1 (2.1) | 14.3 (2) | 0.061 |
| LDL (mg/dL), mean (±SD) | 111.08 (±42) | 115.28 (±43.59) | 110.70 (±41.86) | 0.12 |
| HbA1c (%), median (IQR) | 5.8 (1.2) | 5.8 (1.1) | 5.8 (1.2) | 0.55 |
| EuroSCORE II, median (IQR) | 1.26 (1.36) | 1.53 (2.19) | 1.25 (1.31) | <0.001 |
| LVEF baseline (%), median (IQR) | 58 (13) | 57 (12) | 58 (13) | 0.69 |
| COPD, n (%) | 228 (4.84) | 12 (3.1) | 216 (5.03) | <0.001 |
| History of AF, n (%) | 2 30 (4.91) | 28 (7.23) | 202 (4.71) | <0.001 |
| Prior cardiac surgery, n (%) | 177 (3.78) | 33 (8.53) | 144 (3.36) | <0.001 |
| Arterial hypertension, n (%) | 4160 (88.81) | 350 (90.44) | 3803 (88.65) | <0.001 |
| Diabetes, n (%) | 1739 (37.13) | 142 (36.69) | 1593 (37.13) | <0.001 |
| PAD, n (%) | 581 (12.40) | 60 (15.50) | 520 (12.12) | <0.001 |
| Smoking, n (%) | 2012 (42.96) | 162 (41.86) | 1846 (43.04) | <0.001 |
| Prior stroke, n (%) | 161 (3.44) | 12 (3.1) | 149 (3.47) | <0.001 |
| Chronic dialysis, n (%) | 65 (1.39) | 8 (2.07) | 57 (1.33) | <0.001 |
| History of PCI, n (%) | 1448 (30.91) | 126 (32.56) | 1319 (30.75) | 0.01 |
| History of MI, n (%) | 1016 (21.69) | 88 (22.74) | 927 (21.61) | <0.001 |
| CPB use, n (%) | 692 (14.77) | 128 (33.07) | 564 (13.15) | <0.001 |
| Time on CBP (min), median (IQR) | 84.5 (38) | 91 (51) | 84 (36) | 0.33 |
| Aortic cross-clamp time (min), median (IQR) | 62 (28) | 70 (38.75) | 61 (28) | 0.03 |
| Duration of procedure (min), median (IQR) | 198 (64) | 226 (84.5) | 196 (64) | <0.001 |
| LIMA bypass, n (%) | 4418 (94.32) | 348 (89.92) | 4063 (94.71) | <0.001 |
| Total arterial bypasses, n (%) | 1199 (25.60) | 73 (18.86) | 1125 (26.22) | <0.001 |
| Length of ICU stay (h), median (IQR) | 23 (26) | 47 (89.75) | 22 (22) | <0.001 |
| Duration on ventilator (h), median (IQR) | 7.98 (4.66) | 10.36 (11.85) | 7.83 (4.34) | <0.001 |
| Length of hospitalization (days), median (IQR) | 12 (3) | 13 (5.5) | 12 (13) | <0.001 |
SD, standard deviation; IQR, interquartile range; BMI, body mass index; CCS, Canadian Cardiovascular Society; eGFR, estimated glomerular filtration rate, according to the Modification of Diet in Renal Disease equation; LDL, low-density lipoprotein; HbA1c, glycated haemoglobin; LVEF, left ventricular ejection fraction; COPD, chronic obstructive pulmonary disease; AF, atrial fibrillation; PAD, peripheral arterial disease; PCI, percutaneous coronary intervention; MI, myocardial infarction; CPB, cardiopulmonary bypass; LIMA, left internal mammary artery; hs-cTnI, high-sensitivity cardiac troponin I; URL, upper reference limit.
P-value for comparing those with peak hs-cTnI > 500×URL versus <500× URL.
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