Table 4

Additional randomized controlled trials of clinician-facing nudges

AuthorStudy contextResultLessons
Montoy et al.45Randomization of clinicians to different prepopulated quantities of discharge prescriptions for opioids in emergency departmentsA lower default quantity was associated with fewer prescriptionsTo minimize possible bias, the study intervention was made without announcement, and prescribers were not informed of the study itself
Manz et al.46A stepped-wedge cluster RCT, with behavioural nudges directed at oncologists, combined with machine learning mortality predictions positively influenced clinician behaviour through initiating more care planning conversationsAbsolute increase of 4% among all patients and 11% in those with high predicted mortalityIntegrating behavioural economic principles into the machine learning-based nudge, as a series of co-interventions including peer comparison, feedback, and opt-out reminders
Sacarny et al.47RCT comparing peer comparison letter vs. placebo letter, across 5055 highest Medicare prescribers of the antipsychotic quetiapineOver 9 months, the treatment arm supplied 11.1% fewer quetiapine days per prescriber vs. the control armEffects were larger than those observed in existing large-scale behavioural interventions, potentially because of the content of the peer comparison letter
AuthorStudy contextResultLessons
Montoy et al.45Randomization of clinicians to different prepopulated quantities of discharge prescriptions for opioids in emergency departmentsA lower default quantity was associated with fewer prescriptionsTo minimize possible bias, the study intervention was made without announcement, and prescribers were not informed of the study itself
Manz et al.46A stepped-wedge cluster RCT, with behavioural nudges directed at oncologists, combined with machine learning mortality predictions positively influenced clinician behaviour through initiating more care planning conversationsAbsolute increase of 4% among all patients and 11% in those with high predicted mortalityIntegrating behavioural economic principles into the machine learning-based nudge, as a series of co-interventions including peer comparison, feedback, and opt-out reminders
Sacarny et al.47RCT comparing peer comparison letter vs. placebo letter, across 5055 highest Medicare prescribers of the antipsychotic quetiapineOver 9 months, the treatment arm supplied 11.1% fewer quetiapine days per prescriber vs. the control armEffects were larger than those observed in existing large-scale behavioural interventions, potentially because of the content of the peer comparison letter

Studies stretch across medical contexts and also include non-digital platforms but with a generalizable lesson to all EHR-based nudges.

Table 4

Additional randomized controlled trials of clinician-facing nudges

AuthorStudy contextResultLessons
Montoy et al.45Randomization of clinicians to different prepopulated quantities of discharge prescriptions for opioids in emergency departmentsA lower default quantity was associated with fewer prescriptionsTo minimize possible bias, the study intervention was made without announcement, and prescribers were not informed of the study itself
Manz et al.46A stepped-wedge cluster RCT, with behavioural nudges directed at oncologists, combined with machine learning mortality predictions positively influenced clinician behaviour through initiating more care planning conversationsAbsolute increase of 4% among all patients and 11% in those with high predicted mortalityIntegrating behavioural economic principles into the machine learning-based nudge, as a series of co-interventions including peer comparison, feedback, and opt-out reminders
Sacarny et al.47RCT comparing peer comparison letter vs. placebo letter, across 5055 highest Medicare prescribers of the antipsychotic quetiapineOver 9 months, the treatment arm supplied 11.1% fewer quetiapine days per prescriber vs. the control armEffects were larger than those observed in existing large-scale behavioural interventions, potentially because of the content of the peer comparison letter
AuthorStudy contextResultLessons
Montoy et al.45Randomization of clinicians to different prepopulated quantities of discharge prescriptions for opioids in emergency departmentsA lower default quantity was associated with fewer prescriptionsTo minimize possible bias, the study intervention was made without announcement, and prescribers were not informed of the study itself
Manz et al.46A stepped-wedge cluster RCT, with behavioural nudges directed at oncologists, combined with machine learning mortality predictions positively influenced clinician behaviour through initiating more care planning conversationsAbsolute increase of 4% among all patients and 11% in those with high predicted mortalityIntegrating behavioural economic principles into the machine learning-based nudge, as a series of co-interventions including peer comparison, feedback, and opt-out reminders
Sacarny et al.47RCT comparing peer comparison letter vs. placebo letter, across 5055 highest Medicare prescribers of the antipsychotic quetiapineOver 9 months, the treatment arm supplied 11.1% fewer quetiapine days per prescriber vs. the control armEffects were larger than those observed in existing large-scale behavioural interventions, potentially because of the content of the peer comparison letter

Studies stretch across medical contexts and also include non-digital platforms but with a generalizable lesson to all EHR-based nudges.

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