Table 2 Open in new tab Results of the...

	Comparison cardiology vs primary physician follow-up
All-cause mortality
Overall cohort (n = 23 879)	520	0.81	0.67–0.98	0.03
Subgroup analyses
Male sex (n = 10 714)	314	0.96	0.74–1.24	0.75
Female sex (n = 13 165)	206	0.65	0.48–0.88	0.005
Age group <45 years (n = 12 326)	91	0.93	0.58–1.5	0.77
Age group 45–70 years (n = 11 553)	429	0.76	0.62–0.94	0.01
Moderate or high complexity cardiac lesion (n = 7324)	210	0.73	0.53–0.997	0.048
Simple cardiac lesion (n = 16 555)	310	0.85	0.66–1.09	0.19
All-cause mortality or major adverse event
Overall cohort (n = 23 879)	2491	0.85	0.78–0.92	<0.001
Subgroup analyses
Male sex (n = 10 714)	1350	0.82	0.73–0.93	0.001
Female sex (n = 13 165)	1141	0.88	0.77–0.998	0.046
Age group <45 years (n = 12 326)	703	0.99	0.84–1.17	0.91
Age group 45–70 years (n = 11 553)	1788	0.77	0.70–0.85	<0.001
Moderate or high complexity cardiac lesion (n = 7324)	872	0.81	0.70–0.94	0.007
Simple cardiac lesion (n = 16 555)	1619	0.85	0.77–0.95	0.003

Comparison cardiology vs primary physician follow-up

Number of events

Hazard ratio

95% CI

P-value

All-cause mortality

Overall cohort (n = 23 879)

520

0.81

0.67–0.98

0.03

Subgroup analyses

Male sex (n = 10 714)

314

0.96

0.74–1.24

0.75

Female sex (n = 13 165)

206

0.65

0.48–0.88

0.005

Age group <45 years (n = 12 326)

0.93

0.58–1.5

0.77

Age group 45–70 years (n = 11 553)

429

0.76

0.62–0.94

0.01

Moderate or high complexity cardiac lesion (n = 7324)

210

0.73

0.53–0.997

0.048

Simple cardiac lesion (n = 16 555)

310

0.85

0.66–1.09

0.19

All-cause mortality or major adverse event

Overall cohort (n = 23 879)

2491

0.85

0.78–0.92

<0.001

Subgroup analyses

Male sex (n = 10 714)

1350

0.82

0.73–0.93

0.001

Female sex (n = 13 165)

1141

0.88

0.77–0.998

0.046

Age group <45 years (n = 12 326)

703

0.99

0.84–1.17

0.91

Age group 45–70 years (n = 11 553)

1788

0.77

0.70–0.85

<0.001

Moderate or high complexity cardiac lesion (n = 7324)

872

0.81

0.70–0.94

0.007

Simple cardiac lesion (n = 16 555)

1619

0.85

0.77–0.95

0.003

	Comparison cardiology vs primary physician follow-up
All-cause mortality
Overall cohort (n = 23 879)	520	0.81	0.67–0.98	0.03
Subgroup analyses
Male sex (n = 10 714)	314	0.96	0.74–1.24	0.75
Female sex (n = 13 165)	206	0.65	0.48–0.88	0.005
Age group <45 years (n = 12 326)	91	0.93	0.58–1.5	0.77
Age group 45–70 years (n = 11 553)	429	0.76	0.62–0.94	0.01
Moderate or high complexity cardiac lesion (n = 7324)	210	0.73	0.53–0.997	0.048
Simple cardiac lesion (n = 16 555)	310	0.85	0.66–1.09	0.19
All-cause mortality or major adverse event
Overall cohort (n = 23 879)	2491	0.85	0.78–0.92	<0.001
Subgroup analyses
Male sex (n = 10 714)	1350	0.82	0.73–0.93	0.001
Female sex (n = 13 165)	1141	0.88	0.77–0.998	0.046
Age group <45 years (n = 12 326)	703	0.99	0.84–1.17	0.91
Age group 45–70 years (n = 11 553)	1788	0.77	0.70–0.85	<0.001
Moderate or high complexity cardiac lesion (n = 7324)	872	0.81	0.70–0.94	0.007
Simple cardiac lesion (n = 16 555)	1619	0.85	0.77–0.95	0.003

Table 2

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Results of the multivariable propensity score adjusted analysis comparing primary care physician vs. cardiology follow-up for the primary (all-cause mortality) and secondary (composite of death or major adverse events) endpoint

	Comparison cardiology vs primary physician follow-up
	Number of events	Hazard ratio	95% CI	P-value
All-cause mortality
Overall cohort (n = 23 879)	520	0.81	0.67–0.98	0.03
Subgroup analyses
Male sex (n = 10 714)	314	0.96	0.74–1.24	0.75
Female sex (n = 13 165)	206	0.65	0.48–0.88	0.005
Age group <45 years (n = 12 326)	91	0.93	0.58–1.5	0.77
Age group 45–70 years (n = 11 553)	429	0.76	0.62–0.94	0.01
Moderate or high complexity cardiac lesion (n = 7324)	210	0.73	0.53–0.997	0.048
Simple cardiac lesion (n = 16 555)	310	0.85	0.66–1.09	0.19
All-cause mortality or major adverse event
Overall cohort (n = 23 879)	2491	0.85	0.78–0.92	<0.001
Subgroup analyses
Male sex (n = 10 714)	1350	0.82	0.73–0.93	0.001
Female sex (n = 13 165)	1141	0.88	0.77–0.998	0.046
Age group <45 years (n = 12 326)	703	0.99	0.84–1.17	0.91
Age group 45–70 years (n = 11 553)	1788	0.77	0.70–0.85	<0.001
Moderate or high complexity cardiac lesion (n = 7324)	872	0.81	0.70–0.94	0.007
Simple cardiac lesion (n = 16 555)	1619	0.85	0.77–0.95	0.003

	Comparison cardiology vs primary physician follow-up
	Number of events	Hazard ratio	95% CI	P-value
All-cause mortality
Overall cohort (n = 23 879)	520	0.81	0.67–0.98	0.03
Subgroup analyses
Male sex (n = 10 714)	314	0.96	0.74–1.24	0.75
Female sex (n = 13 165)	206	0.65	0.48–0.88	0.005
Age group <45 years (n = 12 326)	91	0.93	0.58–1.5	0.77
Age group 45–70 years (n = 11 553)	429	0.76	0.62–0.94	0.01
Moderate or high complexity cardiac lesion (n = 7324)	210	0.73	0.53–0.997	0.048
Simple cardiac lesion (n = 16 555)	310	0.85	0.66–1.09	0.19
All-cause mortality or major adverse event
Overall cohort (n = 23 879)	2491	0.85	0.78–0.92	<0.001
Subgroup analyses
Male sex (n = 10 714)	1350	0.82	0.73–0.93	0.001
Female sex (n = 13 165)	1141	0.88	0.77–0.998	0.046
Age group <45 years (n = 12 326)	703	0.99	0.84–1.17	0.91
Age group 45–70 years (n = 11 553)	1788	0.77	0.70–0.85	<0.001
Moderate or high complexity cardiac lesion (n = 7324)	872	0.81	0.70–0.94	0.007
Simple cardiac lesion (n = 16 555)	1619	0.85	0.77–0.95	0.003

Data are provided for the overall cohort as well as for predefined subgroups of patients. A HR <1 indicates superior survival/freedom from adverse events for the group with cardiology follow-up. Details on the definition of the composite endpoint as well as variables included in the propensity score/multivariable analysis are given in the Methods section as well as Supplementary material online, Table S1. Text in bold identifies significant parameters.

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