Table 1

Baseline characteristics of included patients and the results of coronary computed tomography angiography and invasive coronary angiography preformed within 120 days of the coronary computed tomography angiography

All patients
Number of patients42 328 (100)
Characteristics
 Sex, male19 453 (46.0)
 Age (years)57.3 ± 11.3
  <402820 (6.7)
  40 to <508230 (19.4)
  50 to <6013 106 (30.1)
  60 to <7012 492 (29.5)
  ≥705680 (13.4)
 Smoking
  Never16 513 (39.0)
  Former13 874 (32.8)
  Active8927 (21.1)
  Missing3014 (7.1)
 Hypercholesterolaemia14 966 (35.4)
 Hypertension19 782 (46.7)
 Diabetes3718 (8.8)
 Symptoms
  Typical chest pain5196 (12.3)
  Atypical chest pain20 162 (47.6)
  Non-specific chest pain13 710 (32.4)
  Dyspnoea3260 (7.7)
Pre-test probability models
 2019-ESC-PTP model11% [6–19]
 2013-ESC-PTP model30% [18–48]
 CAD Consortium basic PTP model10% [5–20]
Coronary computed tomography angiography
 Coronary artery calcium scorea0 [0–83]
 Disease severity
  No CAD (no coronary calcium or stenosis)19 544 (46.2)
  Non-obstructive CAD (diameter stenosis <50%)12 769 (30.2)
  Coronary stenosis (diameter stenosis ≥50%)10 015 (23.6)
Invasive coronary angiography and revascularization
 Invasive coronary angiography8028 (19.0)
 Disease severity
  Obstructive coronary CAD (diameter stenosis ≥50% and/or FFR < 0.8)3718 (8.8)
 Revascularization
  Percutaneous coronary intervention1985 (5.2)
  Coronary artery bypass grafting635 (1.6)
All patients
Number of patients42 328 (100)
Characteristics
 Sex, male19 453 (46.0)
 Age (years)57.3 ± 11.3
  <402820 (6.7)
  40 to <508230 (19.4)
  50 to <6013 106 (30.1)
  60 to <7012 492 (29.5)
  ≥705680 (13.4)
 Smoking
  Never16 513 (39.0)
  Former13 874 (32.8)
  Active8927 (21.1)
  Missing3014 (7.1)
 Hypercholesterolaemia14 966 (35.4)
 Hypertension19 782 (46.7)
 Diabetes3718 (8.8)
 Symptoms
  Typical chest pain5196 (12.3)
  Atypical chest pain20 162 (47.6)
  Non-specific chest pain13 710 (32.4)
  Dyspnoea3260 (7.7)
Pre-test probability models
 2019-ESC-PTP model11% [6–19]
 2013-ESC-PTP model30% [18–48]
 CAD Consortium basic PTP model10% [5–20]
Coronary computed tomography angiography
 Coronary artery calcium scorea0 [0–83]
 Disease severity
  No CAD (no coronary calcium or stenosis)19 544 (46.2)
  Non-obstructive CAD (diameter stenosis <50%)12 769 (30.2)
  Coronary stenosis (diameter stenosis ≥50%)10 015 (23.6)
Invasive coronary angiography and revascularization
 Invasive coronary angiography8028 (19.0)
 Disease severity
  Obstructive coronary CAD (diameter stenosis ≥50% and/or FFR < 0.8)3718 (8.8)
 Revascularization
  Percutaneous coronary intervention1985 (5.2)
  Coronary artery bypass grafting635 (1.6)

Values are n (%) or mean ± SD or median [interquartile range].

CAD, coronary artery disease; ESC, European Society of Cardiology; FFR, fractional flow reserve; PTP, pre-test probability; SD, standard deviation.

a

Coronary artery calcium score was missing in 6.7% of the patients.

Table 1

Baseline characteristics of included patients and the results of coronary computed tomography angiography and invasive coronary angiography preformed within 120 days of the coronary computed tomography angiography

All patients
Number of patients42 328 (100)
Characteristics
 Sex, male19 453 (46.0)
 Age (years)57.3 ± 11.3
  <402820 (6.7)
  40 to <508230 (19.4)
  50 to <6013 106 (30.1)
  60 to <7012 492 (29.5)
  ≥705680 (13.4)
 Smoking
  Never16 513 (39.0)
  Former13 874 (32.8)
  Active8927 (21.1)
  Missing3014 (7.1)
 Hypercholesterolaemia14 966 (35.4)
 Hypertension19 782 (46.7)
 Diabetes3718 (8.8)
 Symptoms
  Typical chest pain5196 (12.3)
  Atypical chest pain20 162 (47.6)
  Non-specific chest pain13 710 (32.4)
  Dyspnoea3260 (7.7)
Pre-test probability models
 2019-ESC-PTP model11% [6–19]
 2013-ESC-PTP model30% [18–48]
 CAD Consortium basic PTP model10% [5–20]
Coronary computed tomography angiography
 Coronary artery calcium scorea0 [0–83]
 Disease severity
  No CAD (no coronary calcium or stenosis)19 544 (46.2)
  Non-obstructive CAD (diameter stenosis <50%)12 769 (30.2)
  Coronary stenosis (diameter stenosis ≥50%)10 015 (23.6)
Invasive coronary angiography and revascularization
 Invasive coronary angiography8028 (19.0)
 Disease severity
  Obstructive coronary CAD (diameter stenosis ≥50% and/or FFR < 0.8)3718 (8.8)
 Revascularization
  Percutaneous coronary intervention1985 (5.2)
  Coronary artery bypass grafting635 (1.6)
All patients
Number of patients42 328 (100)
Characteristics
 Sex, male19 453 (46.0)
 Age (years)57.3 ± 11.3
  <402820 (6.7)
  40 to <508230 (19.4)
  50 to <6013 106 (30.1)
  60 to <7012 492 (29.5)
  ≥705680 (13.4)
 Smoking
  Never16 513 (39.0)
  Former13 874 (32.8)
  Active8927 (21.1)
  Missing3014 (7.1)
 Hypercholesterolaemia14 966 (35.4)
 Hypertension19 782 (46.7)
 Diabetes3718 (8.8)
 Symptoms
  Typical chest pain5196 (12.3)
  Atypical chest pain20 162 (47.6)
  Non-specific chest pain13 710 (32.4)
  Dyspnoea3260 (7.7)
Pre-test probability models
 2019-ESC-PTP model11% [6–19]
 2013-ESC-PTP model30% [18–48]
 CAD Consortium basic PTP model10% [5–20]
Coronary computed tomography angiography
 Coronary artery calcium scorea0 [0–83]
 Disease severity
  No CAD (no coronary calcium or stenosis)19 544 (46.2)
  Non-obstructive CAD (diameter stenosis <50%)12 769 (30.2)
  Coronary stenosis (diameter stenosis ≥50%)10 015 (23.6)
Invasive coronary angiography and revascularization
 Invasive coronary angiography8028 (19.0)
 Disease severity
  Obstructive coronary CAD (diameter stenosis ≥50% and/or FFR < 0.8)3718 (8.8)
 Revascularization
  Percutaneous coronary intervention1985 (5.2)
  Coronary artery bypass grafting635 (1.6)

Values are n (%) or mean ± SD or median [interquartile range].

CAD, coronary artery disease; ESC, European Society of Cardiology; FFR, fractional flow reserve; PTP, pre-test probability; SD, standard deviation.

a

Coronary artery calcium score was missing in 6.7% of the patients.

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