Amiodarone differentially affects viral progeny release of negative-strand and positive-strand RNA viruses
| Amiodarone (µM) . | CCHFV (focus-forming units/mL) . | DENV4 (pfu/mL) . | EV8362 (pfu/mL) . |
|---|---|---|---|
| 0 | 6.0 × 108 | 3.8 × 105 | 1.3 × 105 |
| 5 | 7.4 × 108 | 6.0 × 105 | 2.3 × 106 |
| 10 | 3.5 × 108 | 6.6 × 105 | 2.7 × 106 |
| Amiodarone (µM) . | CCHFV (focus-forming units/mL) . | DENV4 (pfu/mL) . | EV8362 (pfu/mL) . |
|---|---|---|---|
| 0 | 6.0 × 108 | 3.8 × 105 | 1.3 × 105 |
| 5 | 7.4 × 108 | 6.0 × 105 | 2.3 × 106 |
| 10 | 3.5 × 108 | 6.6 × 105 | 2.7 × 106 |
CCHFV, Crimean–Congo haemorrhagic fever virus; pfu, plaque-forming unit.
Values represent the mean of two replicates of a representative experiment performed for each virus. The experiments were performed at least three times for each virus.
Amiodarone differentially affects viral progeny release of negative-strand and positive-strand RNA viruses
| Amiodarone (µM) . | CCHFV (focus-forming units/mL) . | DENV4 (pfu/mL) . | EV8362 (pfu/mL) . |
|---|---|---|---|
| 0 | 6.0 × 108 | 3.8 × 105 | 1.3 × 105 |
| 5 | 7.4 × 108 | 6.0 × 105 | 2.3 × 106 |
| 10 | 3.5 × 108 | 6.6 × 105 | 2.7 × 106 |
| Amiodarone (µM) . | CCHFV (focus-forming units/mL) . | DENV4 (pfu/mL) . | EV8362 (pfu/mL) . |
|---|---|---|---|
| 0 | 6.0 × 108 | 3.8 × 105 | 1.3 × 105 |
| 5 | 7.4 × 108 | 6.0 × 105 | 2.3 × 106 |
| 10 | 3.5 × 108 | 6.6 × 105 | 2.7 × 106 |
CCHFV, Crimean–Congo haemorrhagic fever virus; pfu, plaque-forming unit.
Values represent the mean of two replicates of a representative experiment performed for each virus. The experiments were performed at least three times for each virus.
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