| . | Bayard 2004a [27] . | Bayard 2004b [27] . | Chaparro 1998 [15] . | Ferres 2007 [29] . | Pini 2003 [12] . | Ruo 1994 [34] . | Vitek 1996 [36] . | Williams 1997 [38] . |
|---|---|---|---|---|---|---|---|---|
| Domains | ||||||||
| Confounding | Critical | Critical | Critical | Serious | Critical | Serious | Critical | Critical |
| Selection | Serious | Serious | Low | Moderate | Moderate | Moderate | Moderate | Critical |
| Measurement of exposures | Critical | Critical | Critical | Moderate | Critical | Serious | Critical | Critical |
| Departures from exposures | Serious | Serious | Serious | Moderate | Serious | Serious | Serious | Serious |
| Missing data | Moderate | Serious | Moderate | Moderate | Moderate | Serious | Low | Moderate |
| Measurement of outcomes | Moderate | Moderate | Low | Low | Low | Low | Moderate | Low |
| Reported results | Moderate | Low | Low | Low | Low | Low | Low | Low |
| Overall bias | Critical | Critical | Critical | Serious | Critical | Serious | Critical | Critical |
| . | Bayard 2004a [27] . | Bayard 2004b [27] . | Chaparro 1998 [15] . | Ferres 2007 [29] . | Pini 2003 [12] . | Ruo 1994 [34] . | Vitek 1996 [36] . | Williams 1997 [38] . |
|---|---|---|---|---|---|---|---|---|
| Domains | ||||||||
| Confounding | Critical | Critical | Critical | Serious | Critical | Serious | Critical | Critical |
| Selection | Serious | Serious | Low | Moderate | Moderate | Moderate | Moderate | Critical |
| Measurement of exposures | Critical | Critical | Critical | Moderate | Critical | Serious | Critical | Critical |
| Departures from exposures | Serious | Serious | Serious | Moderate | Serious | Serious | Serious | Serious |
| Missing data | Moderate | Serious | Moderate | Moderate | Moderate | Serious | Low | Moderate |
| Measurement of outcomes | Moderate | Moderate | Low | Low | Low | Low | Moderate | Low |
| Reported results | Moderate | Low | Low | Low | Low | Low | Low | Low |
| Overall bias | Critical | Critical | Critical | Serious | Critical | Serious | Critical | Critical |
| . | Bayard 2004a [27] . | Bayard 2004b [27] . | Chaparro 1998 [15] . | Ferres 2007 [29] . | Pini 2003 [12] . | Ruo 1994 [34] . | Vitek 1996 [36] . | Williams 1997 [38] . |
|---|---|---|---|---|---|---|---|---|
| Domains | ||||||||
| Confounding | Critical | Critical | Critical | Serious | Critical | Serious | Critical | Critical |
| Selection | Serious | Serious | Low | Moderate | Moderate | Moderate | Moderate | Critical |
| Measurement of exposures | Critical | Critical | Critical | Moderate | Critical | Serious | Critical | Critical |
| Departures from exposures | Serious | Serious | Serious | Moderate | Serious | Serious | Serious | Serious |
| Missing data | Moderate | Serious | Moderate | Moderate | Moderate | Serious | Low | Moderate |
| Measurement of outcomes | Moderate | Moderate | Low | Low | Low | Low | Moderate | Low |
| Reported results | Moderate | Low | Low | Low | Low | Low | Low | Low |
| Overall bias | Critical | Critical | Critical | Serious | Critical | Serious | Critical | Critical |
| . | Bayard 2004a [27] . | Bayard 2004b [27] . | Chaparro 1998 [15] . | Ferres 2007 [29] . | Pini 2003 [12] . | Ruo 1994 [34] . | Vitek 1996 [36] . | Williams 1997 [38] . |
|---|---|---|---|---|---|---|---|---|
| Domains | ||||||||
| Confounding | Critical | Critical | Critical | Serious | Critical | Serious | Critical | Critical |
| Selection | Serious | Serious | Low | Moderate | Moderate | Moderate | Moderate | Critical |
| Measurement of exposures | Critical | Critical | Critical | Moderate | Critical | Serious | Critical | Critical |
| Departures from exposures | Serious | Serious | Serious | Moderate | Serious | Serious | Serious | Serious |
| Missing data | Moderate | Serious | Moderate | Moderate | Moderate | Serious | Low | Moderate |
| Measurement of outcomes | Moderate | Moderate | Low | Low | Low | Low | Moderate | Low |
| Reported results | Moderate | Low | Low | Low | Low | Low | Low | Low |
| Overall bias | Critical | Critical | Critical | Serious | Critical | Serious | Critical | Critical |
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