| SNP . | Gene . | Risks . | SE(β) . | OR (95% CI) . | P . |
|---|---|---|---|---|---|
| rs3748856 | FAM110D | 0.135 | 0.711 (0.545–0.927) | 0.012 | |
| Age | 0.006 | 1.064 (1.052–1.077) | 4.52 × 10−25 | ||
| BMI | 0.025 | 1.156 (1.100–1.215) | 1.05 × 10−8 | ||
| TC | 0.044 | 1.249 (1.415–1.362) | 5.68 × 10−7 | ||
| TG | 0.049 | 1.137 (1.033–1.251) | 0.009 | ||
| LDL | 0.097 | 1.077 (0.890–1.304) | 0.445 | ||
| rs139118504 | CACNA1A | 0.134 | 1.632 (1.254–2.124) | 2.71 × 10−4 | |
| Age | 0.006 | 1.062 (1.050–1.074) | 3.61 × 10−24 | ||
| BMI | 0.026 | 1.178 (1.121–1.239) | 1.40 × 10−10 | ||
| TC | 0.006 | 1.000 (0.988–1.011) | 0.947 | ||
| TG | 0.051 | 1.209 (1.094–1.336) | 1.89 × 10−4 | ||
| LDL | 0.092 | 1.268 (1.059–1.518) | 0.01 | ||
| rs34436714 | NLRP12 | 0.134 | 1.377 (1.059–1.789) | 0.017 | |
| Age | 0.006 | 1.059 (1.047–1.071) | 1.97 × 10−23 | ||
| BMI | 0.025 | 1.165 (1.109–1.224) | 1.40 × 10−9 | ||
| TC | 0.006 | 1.000 (0.988–1.011) | 0.933 | ||
| TG | 0.052 | 1.224 (1.106–1.354) | 8.92 × 10−5 | ||
| LDL | 0.088 | 1.268 (1.068–1.506) | 0.007 |
| SNP . | Gene . | Risks . | SE(β) . | OR (95% CI) . | P . |
|---|---|---|---|---|---|
| rs3748856 | FAM110D | 0.135 | 0.711 (0.545–0.927) | 0.012 | |
| Age | 0.006 | 1.064 (1.052–1.077) | 4.52 × 10−25 | ||
| BMI | 0.025 | 1.156 (1.100–1.215) | 1.05 × 10−8 | ||
| TC | 0.044 | 1.249 (1.415–1.362) | 5.68 × 10−7 | ||
| TG | 0.049 | 1.137 (1.033–1.251) | 0.009 | ||
| LDL | 0.097 | 1.077 (0.890–1.304) | 0.445 | ||
| rs139118504 | CACNA1A | 0.134 | 1.632 (1.254–2.124) | 2.71 × 10−4 | |
| Age | 0.006 | 1.062 (1.050–1.074) | 3.61 × 10−24 | ||
| BMI | 0.026 | 1.178 (1.121–1.239) | 1.40 × 10−10 | ||
| TC | 0.006 | 1.000 (0.988–1.011) | 0.947 | ||
| TG | 0.051 | 1.209 (1.094–1.336) | 1.89 × 10−4 | ||
| LDL | 0.092 | 1.268 (1.059–1.518) | 0.01 | ||
| rs34436714 | NLRP12 | 0.134 | 1.377 (1.059–1.789) | 0.017 | |
| Age | 0.006 | 1.059 (1.047–1.071) | 1.97 × 10−23 | ||
| BMI | 0.025 | 1.165 (1.109–1.224) | 1.40 × 10−9 | ||
| TC | 0.006 | 1.000 (0.988–1.011) | 0.933 | ||
| TG | 0.052 | 1.224 (1.106–1.354) | 8.92 × 10−5 | ||
| LDL | 0.088 | 1.268 (1.068–1.506) | 0.007 |
P value in boldface indicates statistical significance under the assumption of a dominant model (*P < 0.05).
Abbreviations: BMI, body mass index; CI, confidence interval; LDL, low-density lipoprotein; OR, odds ratio; TC, total cholesterol; TG, triglycerides; SE(β), standard error; SNP, single-nucleotide polymorphism.
| SNP . | Gene . | Risks . | SE(β) . | OR (95% CI) . | P . |
|---|---|---|---|---|---|
| rs3748856 | FAM110D | 0.135 | 0.711 (0.545–0.927) | 0.012 | |
| Age | 0.006 | 1.064 (1.052–1.077) | 4.52 × 10−25 | ||
| BMI | 0.025 | 1.156 (1.100–1.215) | 1.05 × 10−8 | ||
| TC | 0.044 | 1.249 (1.415–1.362) | 5.68 × 10−7 | ||
| TG | 0.049 | 1.137 (1.033–1.251) | 0.009 | ||
| LDL | 0.097 | 1.077 (0.890–1.304) | 0.445 | ||
| rs139118504 | CACNA1A | 0.134 | 1.632 (1.254–2.124) | 2.71 × 10−4 | |
| Age | 0.006 | 1.062 (1.050–1.074) | 3.61 × 10−24 | ||
| BMI | 0.026 | 1.178 (1.121–1.239) | 1.40 × 10−10 | ||
| TC | 0.006 | 1.000 (0.988–1.011) | 0.947 | ||
| TG | 0.051 | 1.209 (1.094–1.336) | 1.89 × 10−4 | ||
| LDL | 0.092 | 1.268 (1.059–1.518) | 0.01 | ||
| rs34436714 | NLRP12 | 0.134 | 1.377 (1.059–1.789) | 0.017 | |
| Age | 0.006 | 1.059 (1.047–1.071) | 1.97 × 10−23 | ||
| BMI | 0.025 | 1.165 (1.109–1.224) | 1.40 × 10−9 | ||
| TC | 0.006 | 1.000 (0.988–1.011) | 0.933 | ||
| TG | 0.052 | 1.224 (1.106–1.354) | 8.92 × 10−5 | ||
| LDL | 0.088 | 1.268 (1.068–1.506) | 0.007 |
| SNP . | Gene . | Risks . | SE(β) . | OR (95% CI) . | P . |
|---|---|---|---|---|---|
| rs3748856 | FAM110D | 0.135 | 0.711 (0.545–0.927) | 0.012 | |
| Age | 0.006 | 1.064 (1.052–1.077) | 4.52 × 10−25 | ||
| BMI | 0.025 | 1.156 (1.100–1.215) | 1.05 × 10−8 | ||
| TC | 0.044 | 1.249 (1.415–1.362) | 5.68 × 10−7 | ||
| TG | 0.049 | 1.137 (1.033–1.251) | 0.009 | ||
| LDL | 0.097 | 1.077 (0.890–1.304) | 0.445 | ||
| rs139118504 | CACNA1A | 0.134 | 1.632 (1.254–2.124) | 2.71 × 10−4 | |
| Age | 0.006 | 1.062 (1.050–1.074) | 3.61 × 10−24 | ||
| BMI | 0.026 | 1.178 (1.121–1.239) | 1.40 × 10−10 | ||
| TC | 0.006 | 1.000 (0.988–1.011) | 0.947 | ||
| TG | 0.051 | 1.209 (1.094–1.336) | 1.89 × 10−4 | ||
| LDL | 0.092 | 1.268 (1.059–1.518) | 0.01 | ||
| rs34436714 | NLRP12 | 0.134 | 1.377 (1.059–1.789) | 0.017 | |
| Age | 0.006 | 1.059 (1.047–1.071) | 1.97 × 10−23 | ||
| BMI | 0.025 | 1.165 (1.109–1.224) | 1.40 × 10−9 | ||
| TC | 0.006 | 1.000 (0.988–1.011) | 0.933 | ||
| TG | 0.052 | 1.224 (1.106–1.354) | 8.92 × 10−5 | ||
| LDL | 0.088 | 1.268 (1.068–1.506) | 0.007 |
P value in boldface indicates statistical significance under the assumption of a dominant model (*P < 0.05).
Abbreviations: BMI, body mass index; CI, confidence interval; LDL, low-density lipoprotein; OR, odds ratio; TC, total cholesterol; TG, triglycerides; SE(β), standard error; SNP, single-nucleotide polymorphism.
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