Table 3

Grade for the overall quality of evidence. Adapted from Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schünemann HJ & GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008 336 924–926. (8)

GradeQuality levelDefinition
AHighWe are confident that the true effects lie close to that of the estimates of the effect
BModerateThe true effects are likely to be close to the estimates of the effects, but there is a possibility that they are substantially different
CLowThe true effects might be substantially different from the estimates of the effects
DVery lowThe estimates are very uncertain and often will be far from the truth
GradeQuality levelDefinition
AHighWe are confident that the true effects lie close to that of the estimates of the effect
BModerateThe true effects are likely to be close to the estimates of the effects, but there is a possibility that they are substantially different
CLowThe true effects might be substantially different from the estimates of the effects
DVery lowThe estimates are very uncertain and often will be far from the truth
Table 3

Grade for the overall quality of evidence. Adapted from Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schünemann HJ & GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008 336 924–926. (8)

GradeQuality levelDefinition
AHighWe are confident that the true effects lie close to that of the estimates of the effect
BModerateThe true effects are likely to be close to the estimates of the effects, but there is a possibility that they are substantially different
CLowThe true effects might be substantially different from the estimates of the effects
DVery lowThe estimates are very uncertain and often will be far from the truth
GradeQuality levelDefinition
AHighWe are confident that the true effects lie close to that of the estimates of the effect
BModerateThe true effects are likely to be close to the estimates of the effects, but there is a possibility that they are substantially different
CLowThe true effects might be substantially different from the estimates of the effects
DVery lowThe estimates are very uncertain and often will be far from the truth
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