Table 1 Open in new tab Overall...

MRI findings

All raters
(N = 35)

Neuroradiologists and neurologists (N = 26)

Neurologists only
(N = 17)

Neuroradiologists only
(N = 9)

P-value between neurologists and neuroradiologists

Number of Kappa analysis

N = 595

N = 325

N = 136

N = 36

LM-related items

Brain nodules

0.47
(0.3–0.6)

0.42
(0.25–0.56)

0.42
(0.26–0.6)

0.39
(0.27–0.59)

.4940

Brain linear disease

0.45
(0.31–0.58)

0.5
(0.38–0.64)

0.48
(0.34–0.62)

0.59
(0.45–0.7)

.0039

Hydrocephalus

0.63
(0.44–0.77)

0.69
(0.53–0.85)

0.69
(0.54–0.86)

0.66
(0.5–0.82)

.1800

Evan’s index, cut-off 0.27

0.69
(0.57–0.79)

0.69
(0.47–0.79)

0.77
(0.68–0.86)

.0080

Evan’s index, cut-off 0.30

0.75
(0.58–0.88)

0.78
(0.67–0.89)

0.76
(0.58–0.89)

0.83
(0.72–0.89)

.0588

Spinal nodules

0.63
(0.43–0.76)

0.63
(0.42–0.76)

0.6
(0.39–0.76)

0.64
(0.55–0.76)

.0793

Spinal linear disease

0.46
(0.29–0.6)

0.46
(0.29–0.58)

0.5
(0.34–0.63)

0.43
(0.23–0.55)

.0185

Non-LM-related items

Brain parenchymal metastases

0.29
(0.12–0.45)

0.3
(0.13–0.45)

0.24
(0.11–0.45)

0.41
(0.31–0.52)

.0002

Table 1

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Overall Concordance Rate for Single Items of the Scorecard Using Simple Kappa Coefficient: Median (Lower-Upper Quartile) at Baseline

MRI findings	All raters (N = 35)	Neuroradiologists and neurologists (N = 26)	Neurologists only (N = 17)	Neuroradiologists only (N = 9)	P-value between neurologists and neuroradiologists
Number of Kappa analysis	N = 595	N = 325	N = 136	N = 36
LM-related items
Brain nodules	0.47 (0.3–0.6)	0.42 (0.25–0.56)	0.42 (0.26–0.6)	0.39 (0.27–0.59)	.4940
Brain linear disease	0.45 (0.31–0.58)	0.5 (0.38–0.64)	0.48 (0.34–0.62)	0.59 (0.45–0.7)	.0039
Hydrocephalus	0.63 (0.44–0.77)	0.69 (0.53–0.85)	0.69 (0.54–0.86)	0.66 (0.5–0.82)	.1800
Evan’s index, cut-off 0.27	0.69 (0.57–0.79)	0.69 (0.57–0.79)	0.69 (0.47–0.79)	0.77 (0.68–0.86)	.0080
Evan’s index, cut-off 0.30	0.75 (0.58–0.88)	0.78 (0.67–0.89)	0.76 (0.58–0.89)	0.83 (0.72–0.89)	.0588
Spinal nodules	0.63 (0.43–0.76)	0.63 (0.42–0.76)	0.6 (0.39–0.76)	0.64 (0.55–0.76)	.0793
Spinal linear disease	0.46 (0.29–0.6)	0.46 (0.29–0.58)	0.5 (0.34–0.63)	0.43 (0.23–0.55)	.0185
Non-LM-related items
Brain parenchymal metastases	0.29 (0.12–0.45)	0.3 (0.13–0.45)	0.24 (0.11–0.45)	0.41 (0.31–0.52)	.0002

MRI findings	All raters (N = 35)	Neuroradiologists and neurologists (N = 26)	Neurologists only (N = 17)	Neuroradiologists only (N = 9)	P-value between neurologists and neuroradiologists
Number of Kappa analysis	N = 595	N = 325	N = 136	N = 36
LM-related items
Brain nodules	0.47 (0.3–0.6)	0.42 (0.25–0.56)	0.42 (0.26–0.6)	0.39 (0.27–0.59)	.4940
Brain linear disease	0.45 (0.31–0.58)	0.5 (0.38–0.64)	0.48 (0.34–0.62)	0.59 (0.45–0.7)	.0039
Hydrocephalus	0.63 (0.44–0.77)	0.69 (0.53–0.85)	0.69 (0.54–0.86)	0.66 (0.5–0.82)	.1800
Evan’s index, cut-off 0.27	0.69 (0.57–0.79)	0.69 (0.57–0.79)	0.69 (0.47–0.79)	0.77 (0.68–0.86)	.0080
Evan’s index, cut-off 0.30	0.75 (0.58–0.88)	0.78 (0.67–0.89)	0.76 (0.58–0.89)	0.83 (0.72–0.89)	.0588
Spinal nodules	0.63 (0.43–0.76)	0.63 (0.42–0.76)	0.6 (0.39–0.76)	0.64 (0.55–0.76)	.0793
Spinal linear disease	0.46 (0.29–0.6)	0.46 (0.29–0.58)	0.5 (0.34–0.63)	0.43 (0.23–0.55)	.0185
Non-LM-related items
Brain parenchymal metastases	0.29 (0.12–0.45)	0.3 (0.13–0.45)	0.24 (0.11–0.45)	0.41 (0.31–0.52)	.0002

LM, leptomeningeal metastasis; N, number

Evan’s index 0.27: cut-off inferior to 0.27 versus equal or superior to 0.27; Evan’s index 0.30: cut-off inferior to 0.30 versus equal or superior to 0.30

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