Table 1

Baseline characteristics before and after PSM, n (%)

VariablesBefore PSMAfter PSM
TotalNon-VPI
N = 1044
VPI
N = 372
PNon-VPI
N = 339
VPI
N = 339
P
Age (years)0.0900.864
 <65418 (29.52)321 (30.75)97 (26.08)93 (27.43)95 (28.02)
 ≥65998 (70.48)723 (69.25)275 (73.92)246 (72.57)244 (71.98)
Sex0.5770.758
 Female660 (46.61)482 (46.17)178 (47.85)154 (45.43)158 (46.61)
 Male756 (53.39)562 (53.83)194 (52.15)185 (54.57)181 (53.39)
Race0.0340.533
 White1216 (85.88)883 (84.58)333 (89.52)296 (87.32)300 (88.50)
 Black121 (8.55)94 (9.00)27 (7.26)34 (10.03)27 (7.96)
 Others79 (5.58)67 (6.42)12 (3.23)9 (2.65)12 (3.54)
Marital status0.0420.983
 Married799 (56.43)601 (57.57)198 (53.23)179 (52.80)184 (54.28)
 Single165 (11.65)129 (12.36)36 (9.68)36 (10.62)34 (10.03)
 Separated401 (28.32)282 (27.01)119 (31.99)112 (33.04)109 (32.15)
 Unknown51 (3.60)32 (3.07)19 (5.11)12 (3.54)12 (3.54)
Laterality0.5540.588
 Left602 (42.51)439 (42.05)163 (43.82)146 (43.07)153 (45.13)
 Right814 (57.49)605 (57.95)209 (56.18)193 (56.93)186 (54.87)
Location<0.0010.473
 Main bronchus30 (2.12)26 (2.49)4 (1.08)3 (0.88)4 (1.18)
 Upper lobe, lung783 (55.30)583 (55.84)200 (53.76)206 (60.77)189 (55.75)
 Middle lobe, lung54 (3.81)26 (2.49)28 (7.53)15 (4.42)17 (5.01)
 Lower lobe, lung415 (29.31)298 (28.54)117 (31.45)98 (28.91)107 (31.56)
 Overlapping lesion of lung23 (1.62)17 (1.63)6 (1.61)8 (2.36)5 (1.47)
 Lung, NOS111 (7.84)94 (9.00)17 (4.57)9 (2.65)17 (5.01)
Grade<0.0010.406
 I/II187 (13.21)158 (15.13)29 (7.80)33 (9.73)29 (8.55)
 III360 (25.42)254 (24.33)106 (28.49)100 (29.50)97 (28.61)
 IV246 (17.37)154 (14.75)92 (24.73)86 (25.37)73 (21.53)
 Unknown623 (44.00)478 (45.79)145 (38.98)120 (35.40)140 (41.30)
Number of nodes involved0.0160.346
 ≤9831 (58.69)593 (56.80)238 (63.98)198 (58.41)210 (61.95)
 ≥10585 (41.31)451 (43.20)134 (36.02)141 (41.59)129 (38.05)
Tumour size0.0010.345
 0 ~ 3.0 cm1034 (73.02)788 (75.48)246 (66.13)241 (71.09)232 (68.44)
 3.1–5.0 cm277 (19.56)179 (17.15)98 (26.34)68 (20.06)85 (25.07)
 5.1–7.0 cm64 (4.52)49 (4.69)15 (4.03)17 (5.01)13 (3.83)
 >7 cm41 (2.90)28 (2.68)13 (3.49)13 (3.83)9 (2.65)
Nodal stage<0.0010.879
N01109 (78.32)853 (81.70)256 (68.82)237 (69.91)243 (71.68)
N1175 (12.36)112 (10.73)63 (16.94)54 (15.93)51 (15.04)
N2132 (9.32)79 (7.57)53 (14.25)48 (14.16)45 (13.27)
Surgery0.0120.952
 Sublobar resection394 (27.82)270 (25.86)124 (33.33)110 (32.45)108 (31.86)
 Lobectomy980 (69.21)739 (70.79)241 (64.78)223 (65.78)224 (66.08)
 Pneumonectomy42 (2.97)35 (3.35)7 (1.88)6 (1.77)7 (2.06)
PORT<0.0011.000
 No1159 (81.85)883 (84.58)276 (74.19)256 (75.52)256 (75.52)
 Yes257 (18.15)161 (15.42)96 (25.81)83 (24.48)83 (24.48)
Adjuvant chemotherapy<0.0010.758
 No824 (58.19)656 (62.84)168 (45.16)165 (48.67)161 (47.49)
 Yes592 (41.81)388 (37.16)204 (54.84)174 (51.33)178 (52.51)
VariablesBefore PSMAfter PSM
TotalNon-VPI
N = 1044
VPI
N = 372
PNon-VPI
N = 339
VPI
N = 339
P
Age (years)0.0900.864
 <65418 (29.52)321 (30.75)97 (26.08)93 (27.43)95 (28.02)
 ≥65998 (70.48)723 (69.25)275 (73.92)246 (72.57)244 (71.98)
Sex0.5770.758
 Female660 (46.61)482 (46.17)178 (47.85)154 (45.43)158 (46.61)
 Male756 (53.39)562 (53.83)194 (52.15)185 (54.57)181 (53.39)
Race0.0340.533
 White1216 (85.88)883 (84.58)333 (89.52)296 (87.32)300 (88.50)
 Black121 (8.55)94 (9.00)27 (7.26)34 (10.03)27 (7.96)
 Others79 (5.58)67 (6.42)12 (3.23)9 (2.65)12 (3.54)
Marital status0.0420.983
 Married799 (56.43)601 (57.57)198 (53.23)179 (52.80)184 (54.28)
 Single165 (11.65)129 (12.36)36 (9.68)36 (10.62)34 (10.03)
 Separated401 (28.32)282 (27.01)119 (31.99)112 (33.04)109 (32.15)
 Unknown51 (3.60)32 (3.07)19 (5.11)12 (3.54)12 (3.54)
Laterality0.5540.588
 Left602 (42.51)439 (42.05)163 (43.82)146 (43.07)153 (45.13)
 Right814 (57.49)605 (57.95)209 (56.18)193 (56.93)186 (54.87)
Location<0.0010.473
 Main bronchus30 (2.12)26 (2.49)4 (1.08)3 (0.88)4 (1.18)
 Upper lobe, lung783 (55.30)583 (55.84)200 (53.76)206 (60.77)189 (55.75)
 Middle lobe, lung54 (3.81)26 (2.49)28 (7.53)15 (4.42)17 (5.01)
 Lower lobe, lung415 (29.31)298 (28.54)117 (31.45)98 (28.91)107 (31.56)
 Overlapping lesion of lung23 (1.62)17 (1.63)6 (1.61)8 (2.36)5 (1.47)
 Lung, NOS111 (7.84)94 (9.00)17 (4.57)9 (2.65)17 (5.01)
Grade<0.0010.406
 I/II187 (13.21)158 (15.13)29 (7.80)33 (9.73)29 (8.55)
 III360 (25.42)254 (24.33)106 (28.49)100 (29.50)97 (28.61)
 IV246 (17.37)154 (14.75)92 (24.73)86 (25.37)73 (21.53)
 Unknown623 (44.00)478 (45.79)145 (38.98)120 (35.40)140 (41.30)
Number of nodes involved0.0160.346
 ≤9831 (58.69)593 (56.80)238 (63.98)198 (58.41)210 (61.95)
 ≥10585 (41.31)451 (43.20)134 (36.02)141 (41.59)129 (38.05)
Tumour size0.0010.345
 0 ~ 3.0 cm1034 (73.02)788 (75.48)246 (66.13)241 (71.09)232 (68.44)
 3.1–5.0 cm277 (19.56)179 (17.15)98 (26.34)68 (20.06)85 (25.07)
 5.1–7.0 cm64 (4.52)49 (4.69)15 (4.03)17 (5.01)13 (3.83)
 >7 cm41 (2.90)28 (2.68)13 (3.49)13 (3.83)9 (2.65)
Nodal stage<0.0010.879
N01109 (78.32)853 (81.70)256 (68.82)237 (69.91)243 (71.68)
N1175 (12.36)112 (10.73)63 (16.94)54 (15.93)51 (15.04)
N2132 (9.32)79 (7.57)53 (14.25)48 (14.16)45 (13.27)
Surgery0.0120.952
 Sublobar resection394 (27.82)270 (25.86)124 (33.33)110 (32.45)108 (31.86)
 Lobectomy980 (69.21)739 (70.79)241 (64.78)223 (65.78)224 (66.08)
 Pneumonectomy42 (2.97)35 (3.35)7 (1.88)6 (1.77)7 (2.06)
PORT<0.0011.000
 No1159 (81.85)883 (84.58)276 (74.19)256 (75.52)256 (75.52)
 Yes257 (18.15)161 (15.42)96 (25.81)83 (24.48)83 (24.48)
Adjuvant chemotherapy<0.0010.758
 No824 (58.19)656 (62.84)168 (45.16)165 (48.67)161 (47.49)
 Yes592 (41.81)388 (37.16)204 (54.84)174 (51.33)178 (52.51)

PSM, propensity score matching; VPI, visceral pleural invasion; NOS, not otherwise specified; PORT, post-operative radiotherapy.

Table 1

Baseline characteristics before and after PSM, n (%)

VariablesBefore PSMAfter PSM
TotalNon-VPI
N = 1044
VPI
N = 372
PNon-VPI
N = 339
VPI
N = 339
P
Age (years)0.0900.864
 <65418 (29.52)321 (30.75)97 (26.08)93 (27.43)95 (28.02)
 ≥65998 (70.48)723 (69.25)275 (73.92)246 (72.57)244 (71.98)
Sex0.5770.758
 Female660 (46.61)482 (46.17)178 (47.85)154 (45.43)158 (46.61)
 Male756 (53.39)562 (53.83)194 (52.15)185 (54.57)181 (53.39)
Race0.0340.533
 White1216 (85.88)883 (84.58)333 (89.52)296 (87.32)300 (88.50)
 Black121 (8.55)94 (9.00)27 (7.26)34 (10.03)27 (7.96)
 Others79 (5.58)67 (6.42)12 (3.23)9 (2.65)12 (3.54)
Marital status0.0420.983
 Married799 (56.43)601 (57.57)198 (53.23)179 (52.80)184 (54.28)
 Single165 (11.65)129 (12.36)36 (9.68)36 (10.62)34 (10.03)
 Separated401 (28.32)282 (27.01)119 (31.99)112 (33.04)109 (32.15)
 Unknown51 (3.60)32 (3.07)19 (5.11)12 (3.54)12 (3.54)
Laterality0.5540.588
 Left602 (42.51)439 (42.05)163 (43.82)146 (43.07)153 (45.13)
 Right814 (57.49)605 (57.95)209 (56.18)193 (56.93)186 (54.87)
Location<0.0010.473
 Main bronchus30 (2.12)26 (2.49)4 (1.08)3 (0.88)4 (1.18)
 Upper lobe, lung783 (55.30)583 (55.84)200 (53.76)206 (60.77)189 (55.75)
 Middle lobe, lung54 (3.81)26 (2.49)28 (7.53)15 (4.42)17 (5.01)
 Lower lobe, lung415 (29.31)298 (28.54)117 (31.45)98 (28.91)107 (31.56)
 Overlapping lesion of lung23 (1.62)17 (1.63)6 (1.61)8 (2.36)5 (1.47)
 Lung, NOS111 (7.84)94 (9.00)17 (4.57)9 (2.65)17 (5.01)
Grade<0.0010.406
 I/II187 (13.21)158 (15.13)29 (7.80)33 (9.73)29 (8.55)
 III360 (25.42)254 (24.33)106 (28.49)100 (29.50)97 (28.61)
 IV246 (17.37)154 (14.75)92 (24.73)86 (25.37)73 (21.53)
 Unknown623 (44.00)478 (45.79)145 (38.98)120 (35.40)140 (41.30)
Number of nodes involved0.0160.346
 ≤9831 (58.69)593 (56.80)238 (63.98)198 (58.41)210 (61.95)
 ≥10585 (41.31)451 (43.20)134 (36.02)141 (41.59)129 (38.05)
Tumour size0.0010.345
 0 ~ 3.0 cm1034 (73.02)788 (75.48)246 (66.13)241 (71.09)232 (68.44)
 3.1–5.0 cm277 (19.56)179 (17.15)98 (26.34)68 (20.06)85 (25.07)
 5.1–7.0 cm64 (4.52)49 (4.69)15 (4.03)17 (5.01)13 (3.83)
 >7 cm41 (2.90)28 (2.68)13 (3.49)13 (3.83)9 (2.65)
Nodal stage<0.0010.879
N01109 (78.32)853 (81.70)256 (68.82)237 (69.91)243 (71.68)
N1175 (12.36)112 (10.73)63 (16.94)54 (15.93)51 (15.04)
N2132 (9.32)79 (7.57)53 (14.25)48 (14.16)45 (13.27)
Surgery0.0120.952
 Sublobar resection394 (27.82)270 (25.86)124 (33.33)110 (32.45)108 (31.86)
 Lobectomy980 (69.21)739 (70.79)241 (64.78)223 (65.78)224 (66.08)
 Pneumonectomy42 (2.97)35 (3.35)7 (1.88)6 (1.77)7 (2.06)
PORT<0.0011.000
 No1159 (81.85)883 (84.58)276 (74.19)256 (75.52)256 (75.52)
 Yes257 (18.15)161 (15.42)96 (25.81)83 (24.48)83 (24.48)
Adjuvant chemotherapy<0.0010.758
 No824 (58.19)656 (62.84)168 (45.16)165 (48.67)161 (47.49)
 Yes592 (41.81)388 (37.16)204 (54.84)174 (51.33)178 (52.51)
VariablesBefore PSMAfter PSM
TotalNon-VPI
N = 1044
VPI
N = 372
PNon-VPI
N = 339
VPI
N = 339
P
Age (years)0.0900.864
 <65418 (29.52)321 (30.75)97 (26.08)93 (27.43)95 (28.02)
 ≥65998 (70.48)723 (69.25)275 (73.92)246 (72.57)244 (71.98)
Sex0.5770.758
 Female660 (46.61)482 (46.17)178 (47.85)154 (45.43)158 (46.61)
 Male756 (53.39)562 (53.83)194 (52.15)185 (54.57)181 (53.39)
Race0.0340.533
 White1216 (85.88)883 (84.58)333 (89.52)296 (87.32)300 (88.50)
 Black121 (8.55)94 (9.00)27 (7.26)34 (10.03)27 (7.96)
 Others79 (5.58)67 (6.42)12 (3.23)9 (2.65)12 (3.54)
Marital status0.0420.983
 Married799 (56.43)601 (57.57)198 (53.23)179 (52.80)184 (54.28)
 Single165 (11.65)129 (12.36)36 (9.68)36 (10.62)34 (10.03)
 Separated401 (28.32)282 (27.01)119 (31.99)112 (33.04)109 (32.15)
 Unknown51 (3.60)32 (3.07)19 (5.11)12 (3.54)12 (3.54)
Laterality0.5540.588
 Left602 (42.51)439 (42.05)163 (43.82)146 (43.07)153 (45.13)
 Right814 (57.49)605 (57.95)209 (56.18)193 (56.93)186 (54.87)
Location<0.0010.473
 Main bronchus30 (2.12)26 (2.49)4 (1.08)3 (0.88)4 (1.18)
 Upper lobe, lung783 (55.30)583 (55.84)200 (53.76)206 (60.77)189 (55.75)
 Middle lobe, lung54 (3.81)26 (2.49)28 (7.53)15 (4.42)17 (5.01)
 Lower lobe, lung415 (29.31)298 (28.54)117 (31.45)98 (28.91)107 (31.56)
 Overlapping lesion of lung23 (1.62)17 (1.63)6 (1.61)8 (2.36)5 (1.47)
 Lung, NOS111 (7.84)94 (9.00)17 (4.57)9 (2.65)17 (5.01)
Grade<0.0010.406
 I/II187 (13.21)158 (15.13)29 (7.80)33 (9.73)29 (8.55)
 III360 (25.42)254 (24.33)106 (28.49)100 (29.50)97 (28.61)
 IV246 (17.37)154 (14.75)92 (24.73)86 (25.37)73 (21.53)
 Unknown623 (44.00)478 (45.79)145 (38.98)120 (35.40)140 (41.30)
Number of nodes involved0.0160.346
 ≤9831 (58.69)593 (56.80)238 (63.98)198 (58.41)210 (61.95)
 ≥10585 (41.31)451 (43.20)134 (36.02)141 (41.59)129 (38.05)
Tumour size0.0010.345
 0 ~ 3.0 cm1034 (73.02)788 (75.48)246 (66.13)241 (71.09)232 (68.44)
 3.1–5.0 cm277 (19.56)179 (17.15)98 (26.34)68 (20.06)85 (25.07)
 5.1–7.0 cm64 (4.52)49 (4.69)15 (4.03)17 (5.01)13 (3.83)
 >7 cm41 (2.90)28 (2.68)13 (3.49)13 (3.83)9 (2.65)
Nodal stage<0.0010.879
N01109 (78.32)853 (81.70)256 (68.82)237 (69.91)243 (71.68)
N1175 (12.36)112 (10.73)63 (16.94)54 (15.93)51 (15.04)
N2132 (9.32)79 (7.57)53 (14.25)48 (14.16)45 (13.27)
Surgery0.0120.952
 Sublobar resection394 (27.82)270 (25.86)124 (33.33)110 (32.45)108 (31.86)
 Lobectomy980 (69.21)739 (70.79)241 (64.78)223 (65.78)224 (66.08)
 Pneumonectomy42 (2.97)35 (3.35)7 (1.88)6 (1.77)7 (2.06)
PORT<0.0011.000
 No1159 (81.85)883 (84.58)276 (74.19)256 (75.52)256 (75.52)
 Yes257 (18.15)161 (15.42)96 (25.81)83 (24.48)83 (24.48)
Adjuvant chemotherapy<0.0010.758
 No824 (58.19)656 (62.84)168 (45.16)165 (48.67)161 (47.49)
 Yes592 (41.81)388 (37.16)204 (54.84)174 (51.33)178 (52.51)

PSM, propensity score matching; VPI, visceral pleural invasion; NOS, not otherwise specified; PORT, post-operative radiotherapy.

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