Table 5

Best overall response by tumor type (efficacy analysis set)

LesionResponse30 mg (N = 6) n (%)40 mg (N = 7) n (%)
NHL other than ATLNumber of patients53
CR0 (0)1 (33.3)
CRu1 (20.0)1 (33.3)
SD2 (40.0)1 (33.3)
PD2 (40.0)0 (0)
Objective responseCR, CRu or PR1 (20.0)2 (66.7)
Disease controlCR, CRu, PR or SD3 (60.0)3 (100)
ATLNumber of patients14
PR0 (0)3 (75.0)
SD1 (100)1 (25.0)
Objective responseCR or PR0 (0.0)3 (75.0)
Disease controlCR, PR or SD1 (100)4 (100)
LesionResponse30 mg (N = 6) n (%)40 mg (N = 7) n (%)
NHL other than ATLNumber of patients53
CR0 (0)1 (33.3)
CRu1 (20.0)1 (33.3)
SD2 (40.0)1 (33.3)
PD2 (40.0)0 (0)
Objective responseCR, CRu or PR1 (20.0)2 (66.7)
Disease controlCR, CRu, PR or SD3 (60.0)3 (100)
ATLNumber of patients14
PR0 (0)3 (75.0)
SD1 (100)1 (25.0)
Objective responseCR or PR0 (0.0)3 (75.0)
Disease controlCR, PR or SD1 (100)4 (100)

Notes: Patients with no tumor assessment evaluation are considered non-responders. Abbreviations: CR, complete response; CRu, unconfirmed complete response; NHL, non-Hodgkin’s lymphoma; PD, progressive disease; PR, partial response; SD, stable disease.

Table 5

Best overall response by tumor type (efficacy analysis set)

LesionResponse30 mg (N = 6) n (%)40 mg (N = 7) n (%)
NHL other than ATLNumber of patients53
CR0 (0)1 (33.3)
CRu1 (20.0)1 (33.3)
SD2 (40.0)1 (33.3)
PD2 (40.0)0 (0)
Objective responseCR, CRu or PR1 (20.0)2 (66.7)
Disease controlCR, CRu, PR or SD3 (60.0)3 (100)
ATLNumber of patients14
PR0 (0)3 (75.0)
SD1 (100)1 (25.0)
Objective responseCR or PR0 (0.0)3 (75.0)
Disease controlCR, PR or SD1 (100)4 (100)
LesionResponse30 mg (N = 6) n (%)40 mg (N = 7) n (%)
NHL other than ATLNumber of patients53
CR0 (0)1 (33.3)
CRu1 (20.0)1 (33.3)
SD2 (40.0)1 (33.3)
PD2 (40.0)0 (0)
Objective responseCR, CRu or PR1 (20.0)2 (66.7)
Disease controlCR, CRu, PR or SD3 (60.0)3 (100)
ATLNumber of patients14
PR0 (0)3 (75.0)
SD1 (100)1 (25.0)
Objective responseCR or PR0 (0.0)3 (75.0)
Disease controlCR, PR or SD1 (100)4 (100)

Notes: Patients with no tumor assessment evaluation are considered non-responders. Abbreviations: CR, complete response; CRu, unconfirmed complete response; NHL, non-Hodgkin’s lymphoma; PD, progressive disease; PR, partial response; SD, stable disease.

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