Table 1

Characteristics of participants in the sub-cohort (N = 14 663) stratified by physical activity and sex

Physical activity
CharacteristicsInactiveModerately inactiveModerately activeActiveP valuea
Men (n = 5436)
n (%)913(16.8)1737(32.0)1416(26.0)1370(25.2)
Age (years)b55.3 ± 9.052.5 ± 8.551.9 ± 8.550.9 ± 8.8<0.001
Educational level n (%)<0.001
 No schooling (n = 361)70(7.7)103(5.9)97(6.9)91(6.6)
 Primary (n = 1830)315(34.5)506(29.1)490(34.6)519(37.9)
 Secondary (n = 708)114(12.5)249(14.3)196(13.8)149(10.9)
 Vocational/university (n = 2537)414(45.3)879(50.6)633(44.7)611(44.6)
Alcohol consumption n (%)<0.001
 None (n = 420)107(11.7)118(6.8)98(6.9)97(7.1)
 1–≤5 g/day (n = 1030)199(21.8)321(18.5)260(18.4)250(18.2)
 >5–≤10 g/day (n = 748)124(13.6)245(14.1)196(13.8)183(13.4)
 >10–≤40 g/day (n = 2182)327(35.8)716(41.2)577(40.7)562(41.0)
 >40 g/day (n = 1056)156(17.1)337(19.4)285(20.1)278(20.3)
Fruit (g/day)c154.0(216.8)155.2(193.6)153.6(213.9)174.9(230.2)<0.001
Vegetables (g/day)c146.5(156.6)137.5(136.9)151.7(138.7)146.5(148.5)0.091
Body mass index n (%)<0.001
 <25 kg/m2 (n = 1776)249(27.3)556(32.0)477(33.7)494(36.1)
 25–29.9 kg/m2 (n = 2714)460(50.4)893(51.4)701(49.5)660(48.2)
 ≥30 kg/m2 (n = 946)204(22.3)288(16.6)238(16.8)216(15.8)
Total cholesterol n (%)0.004
 <5.2 mmol/L (n = 1498)232(25.4)431(24.8)413(29.2)422(30.8)
 5.2–6.1 mmol/L (n = 2006)335(36.7)667(38.4)523(36.9)481(35.1)
 ≥6.0 mmol/L (n = 1932)346(37.9)639(36.8)480(33.9)467(34.1)
Hypertension n (%)d<0.001
 No (n = 3340)505(55.3)1059(61.0)901(63.6)875(63.9)
 Yes (n = 2096)408(44.7)678(39.0)515(36.4)495(36.1)
History of diabetes n (%)<0.001
 No (n = 5236)858(94.0)1677(96.5)1369(96.7)1332(97.2)
 Yes (n = 200)55(6.0)60(3.5)47(3.3)38(2.8)
Smoking status n (%)<0.001
 Never (n = 1731)234(25.6)573(33.0)468(33.1)456(33.3)
 Former (n = 1964)327(35.8)636(36.6)498(35.2)503(36.7)
 Current (n = 1741)352(38.6)528(30.4)450(31.8)411(30.0)
Women n = 9227
n (%)2449(26.5)3250(35.2)1926(20.9)1602(17.4)
Age (years)b52.4 ± 9.652.1 ± 9.451.3 ± 8.851.5 ± 9.0<0.001
Educational level n (%)<0.001
 No schooling (n = 887)489(20.0)287(8.8)79(4.1)32(2.0)
 Primary (n = 3018)1043(42.6)1016(31.3)518(26.9)441(27.5)
 Secondary (n = 1557)294(12.0)574(17.7)379(19.7)310(19.4)
 Vocational/University (n = 3765)623(25.4)1373(42.2)950(49.3)819(51.1)
Alcohol consumption n (%)<0.001
 None (n = 2018)847(34.6)665(20.5)284(14.7)222(13.9)
 1–≤5 g/day (n = 3364)806(32.9)1240(38.2)745(38.7)573(35.8)
 >5–≤10 g/day (n = 1307)275(11.2)436(13.4)313(16.3)283(17.7)
 >10–≤40 g/day (n = 2298)477(19.5)823(25.3)534(27.7)464(29.0)
 >40 g/day (n = 240)44(1.8)86(2.6)50(2.6)60(3.7)
Fruit (g/day)c250.0(246.1)213.4(211.4)200.9(193.7)216.1(191.5)<0.001
Vegetables (g/day)c178.4(158.1)161.7(133.8)161.3(134.9)154.7(124.7)<0.001
Body mass index n (%)<0.001
 <25 kg/m2 (n = 4629)904(36.9)1666(51.3)1125(58.4)934(58.3)
 25–29.9 kg/m2 (n = 3077)895(36.5)1107(34.1)588(30.5)487(30.4)
 ≥3 kg/m2 (n = 1521)650(26.5)477(14.7)213(11.1)181(11.3)
Total cholesterol n (%)0.142
 <5.2 mmol/L (n = 2588)658(26.9)942(29.0)547(28.4)441(27.5)
 5.2–6.21 mmol/L (n = 3297)875(35.7)1119(34.4)724(37.6)579(36.1)
 ≥6.2 mmol/L (n = 3342)916(37.4)1189(36.6)655(34.0)582(36.3)
Hypertension n (%)d<0.001
 No (n = 6165)1588(64.8)2153(66.2)1372(71.2)1052(65.7)
 Yes (n = 3062)861(35.2)1097(33.8)554(28.8)550(34.3)
History of diabetes n (%)<0.001
 No (n = 9028)2372(96.9)3183(97.9)1890(98.1)1583(98.8)
 Yes (n = 199)77(3.1)67(2.1)36(1.9)19(1.2)
Smoking status n (%)<0.001
 Never (n = 5217)1561(63.7)1831(56.3)1014(52.6)811(50.6)
 Former (n = 1974)359(14.7)704(21.7)475(24.7)436(27.2)
 Current (n = 2036)529(21.6)715(22.0)437(22.7)355(22.2)
Physical activity
CharacteristicsInactiveModerately inactiveModerately activeActiveP valuea
Men (n = 5436)
n (%)913(16.8)1737(32.0)1416(26.0)1370(25.2)
Age (years)b55.3 ± 9.052.5 ± 8.551.9 ± 8.550.9 ± 8.8<0.001
Educational level n (%)<0.001
 No schooling (n = 361)70(7.7)103(5.9)97(6.9)91(6.6)
 Primary (n = 1830)315(34.5)506(29.1)490(34.6)519(37.9)
 Secondary (n = 708)114(12.5)249(14.3)196(13.8)149(10.9)
 Vocational/university (n = 2537)414(45.3)879(50.6)633(44.7)611(44.6)
Alcohol consumption n (%)<0.001
 None (n = 420)107(11.7)118(6.8)98(6.9)97(7.1)
 1–≤5 g/day (n = 1030)199(21.8)321(18.5)260(18.4)250(18.2)
 >5–≤10 g/day (n = 748)124(13.6)245(14.1)196(13.8)183(13.4)
 >10–≤40 g/day (n = 2182)327(35.8)716(41.2)577(40.7)562(41.0)
 >40 g/day (n = 1056)156(17.1)337(19.4)285(20.1)278(20.3)
Fruit (g/day)c154.0(216.8)155.2(193.6)153.6(213.9)174.9(230.2)<0.001
Vegetables (g/day)c146.5(156.6)137.5(136.9)151.7(138.7)146.5(148.5)0.091
Body mass index n (%)<0.001
 <25 kg/m2 (n = 1776)249(27.3)556(32.0)477(33.7)494(36.1)
 25–29.9 kg/m2 (n = 2714)460(50.4)893(51.4)701(49.5)660(48.2)
 ≥30 kg/m2 (n = 946)204(22.3)288(16.6)238(16.8)216(15.8)
Total cholesterol n (%)0.004
 <5.2 mmol/L (n = 1498)232(25.4)431(24.8)413(29.2)422(30.8)
 5.2–6.1 mmol/L (n = 2006)335(36.7)667(38.4)523(36.9)481(35.1)
 ≥6.0 mmol/L (n = 1932)346(37.9)639(36.8)480(33.9)467(34.1)
Hypertension n (%)d<0.001
 No (n = 3340)505(55.3)1059(61.0)901(63.6)875(63.9)
 Yes (n = 2096)408(44.7)678(39.0)515(36.4)495(36.1)
History of diabetes n (%)<0.001
 No (n = 5236)858(94.0)1677(96.5)1369(96.7)1332(97.2)
 Yes (n = 200)55(6.0)60(3.5)47(3.3)38(2.8)
Smoking status n (%)<0.001
 Never (n = 1731)234(25.6)573(33.0)468(33.1)456(33.3)
 Former (n = 1964)327(35.8)636(36.6)498(35.2)503(36.7)
 Current (n = 1741)352(38.6)528(30.4)450(31.8)411(30.0)
Women n = 9227
n (%)2449(26.5)3250(35.2)1926(20.9)1602(17.4)
Age (years)b52.4 ± 9.652.1 ± 9.451.3 ± 8.851.5 ± 9.0<0.001
Educational level n (%)<0.001
 No schooling (n = 887)489(20.0)287(8.8)79(4.1)32(2.0)
 Primary (n = 3018)1043(42.6)1016(31.3)518(26.9)441(27.5)
 Secondary (n = 1557)294(12.0)574(17.7)379(19.7)310(19.4)
 Vocational/University (n = 3765)623(25.4)1373(42.2)950(49.3)819(51.1)
Alcohol consumption n (%)<0.001
 None (n = 2018)847(34.6)665(20.5)284(14.7)222(13.9)
 1–≤5 g/day (n = 3364)806(32.9)1240(38.2)745(38.7)573(35.8)
 >5–≤10 g/day (n = 1307)275(11.2)436(13.4)313(16.3)283(17.7)
 >10–≤40 g/day (n = 2298)477(19.5)823(25.3)534(27.7)464(29.0)
 >40 g/day (n = 240)44(1.8)86(2.6)50(2.6)60(3.7)
Fruit (g/day)c250.0(246.1)213.4(211.4)200.9(193.7)216.1(191.5)<0.001
Vegetables (g/day)c178.4(158.1)161.7(133.8)161.3(134.9)154.7(124.7)<0.001
Body mass index n (%)<0.001
 <25 kg/m2 (n = 4629)904(36.9)1666(51.3)1125(58.4)934(58.3)
 25–29.9 kg/m2 (n = 3077)895(36.5)1107(34.1)588(30.5)487(30.4)
 ≥3 kg/m2 (n = 1521)650(26.5)477(14.7)213(11.1)181(11.3)
Total cholesterol n (%)0.142
 <5.2 mmol/L (n = 2588)658(26.9)942(29.0)547(28.4)441(27.5)
 5.2–6.21 mmol/L (n = 3297)875(35.7)1119(34.4)724(37.6)579(36.1)
 ≥6.2 mmol/L (n = 3342)916(37.4)1189(36.6)655(34.0)582(36.3)
Hypertension n (%)d<0.001
 No (n = 6165)1588(64.8)2153(66.2)1372(71.2)1052(65.7)
 Yes (n = 3062)861(35.2)1097(33.8)554(28.8)550(34.3)
History of diabetes n (%)<0.001
 No (n = 9028)2372(96.9)3183(97.9)1890(98.1)1583(98.8)
 Yes (n = 199)77(3.1)67(2.1)36(1.9)19(1.2)
Smoking status n (%)<0.001
 Never (n = 5217)1561(63.7)1831(56.3)1014(52.6)811(50.6)
 Former (n = 1974)359(14.7)704(21.7)475(24.7)436(27.2)
 Current (n = 2036)529(21.6)715(22.0)437(22.7)355(22.2)
a

P values are derived from a Kruskal Wallis or ANOVA test for continuous variables or from a Chi-square test for categorical variables;

b

Values for normally distributed variables are expressed as mean ± standard deviation;

c

Values from non-normally distributed variables are expressed as median (interquartile range);

d

Hypertension definition is based on medical history and/or clinical measurements.

Table 1

Characteristics of participants in the sub-cohort (N = 14 663) stratified by physical activity and sex

Physical activity
CharacteristicsInactiveModerately inactiveModerately activeActiveP valuea
Men (n = 5436)
n (%)913(16.8)1737(32.0)1416(26.0)1370(25.2)
Age (years)b55.3 ± 9.052.5 ± 8.551.9 ± 8.550.9 ± 8.8<0.001
Educational level n (%)<0.001
 No schooling (n = 361)70(7.7)103(5.9)97(6.9)91(6.6)
 Primary (n = 1830)315(34.5)506(29.1)490(34.6)519(37.9)
 Secondary (n = 708)114(12.5)249(14.3)196(13.8)149(10.9)
 Vocational/university (n = 2537)414(45.3)879(50.6)633(44.7)611(44.6)
Alcohol consumption n (%)<0.001
 None (n = 420)107(11.7)118(6.8)98(6.9)97(7.1)
 1–≤5 g/day (n = 1030)199(21.8)321(18.5)260(18.4)250(18.2)
 >5–≤10 g/day (n = 748)124(13.6)245(14.1)196(13.8)183(13.4)
 >10–≤40 g/day (n = 2182)327(35.8)716(41.2)577(40.7)562(41.0)
 >40 g/day (n = 1056)156(17.1)337(19.4)285(20.1)278(20.3)
Fruit (g/day)c154.0(216.8)155.2(193.6)153.6(213.9)174.9(230.2)<0.001
Vegetables (g/day)c146.5(156.6)137.5(136.9)151.7(138.7)146.5(148.5)0.091
Body mass index n (%)<0.001
 <25 kg/m2 (n = 1776)249(27.3)556(32.0)477(33.7)494(36.1)
 25–29.9 kg/m2 (n = 2714)460(50.4)893(51.4)701(49.5)660(48.2)
 ≥30 kg/m2 (n = 946)204(22.3)288(16.6)238(16.8)216(15.8)
Total cholesterol n (%)0.004
 <5.2 mmol/L (n = 1498)232(25.4)431(24.8)413(29.2)422(30.8)
 5.2–6.1 mmol/L (n = 2006)335(36.7)667(38.4)523(36.9)481(35.1)
 ≥6.0 mmol/L (n = 1932)346(37.9)639(36.8)480(33.9)467(34.1)
Hypertension n (%)d<0.001
 No (n = 3340)505(55.3)1059(61.0)901(63.6)875(63.9)
 Yes (n = 2096)408(44.7)678(39.0)515(36.4)495(36.1)
History of diabetes n (%)<0.001
 No (n = 5236)858(94.0)1677(96.5)1369(96.7)1332(97.2)
 Yes (n = 200)55(6.0)60(3.5)47(3.3)38(2.8)
Smoking status n (%)<0.001
 Never (n = 1731)234(25.6)573(33.0)468(33.1)456(33.3)
 Former (n = 1964)327(35.8)636(36.6)498(35.2)503(36.7)
 Current (n = 1741)352(38.6)528(30.4)450(31.8)411(30.0)
Women n = 9227
n (%)2449(26.5)3250(35.2)1926(20.9)1602(17.4)
Age (years)b52.4 ± 9.652.1 ± 9.451.3 ± 8.851.5 ± 9.0<0.001
Educational level n (%)<0.001
 No schooling (n = 887)489(20.0)287(8.8)79(4.1)32(2.0)
 Primary (n = 3018)1043(42.6)1016(31.3)518(26.9)441(27.5)
 Secondary (n = 1557)294(12.0)574(17.7)379(19.7)310(19.4)
 Vocational/University (n = 3765)623(25.4)1373(42.2)950(49.3)819(51.1)
Alcohol consumption n (%)<0.001
 None (n = 2018)847(34.6)665(20.5)284(14.7)222(13.9)
 1–≤5 g/day (n = 3364)806(32.9)1240(38.2)745(38.7)573(35.8)
 >5–≤10 g/day (n = 1307)275(11.2)436(13.4)313(16.3)283(17.7)
 >10–≤40 g/day (n = 2298)477(19.5)823(25.3)534(27.7)464(29.0)
 >40 g/day (n = 240)44(1.8)86(2.6)50(2.6)60(3.7)
Fruit (g/day)c250.0(246.1)213.4(211.4)200.9(193.7)216.1(191.5)<0.001
Vegetables (g/day)c178.4(158.1)161.7(133.8)161.3(134.9)154.7(124.7)<0.001
Body mass index n (%)<0.001
 <25 kg/m2 (n = 4629)904(36.9)1666(51.3)1125(58.4)934(58.3)
 25–29.9 kg/m2 (n = 3077)895(36.5)1107(34.1)588(30.5)487(30.4)
 ≥3 kg/m2 (n = 1521)650(26.5)477(14.7)213(11.1)181(11.3)
Total cholesterol n (%)0.142
 <5.2 mmol/L (n = 2588)658(26.9)942(29.0)547(28.4)441(27.5)
 5.2–6.21 mmol/L (n = 3297)875(35.7)1119(34.4)724(37.6)579(36.1)
 ≥6.2 mmol/L (n = 3342)916(37.4)1189(36.6)655(34.0)582(36.3)
Hypertension n (%)d<0.001
 No (n = 6165)1588(64.8)2153(66.2)1372(71.2)1052(65.7)
 Yes (n = 3062)861(35.2)1097(33.8)554(28.8)550(34.3)
History of diabetes n (%)<0.001
 No (n = 9028)2372(96.9)3183(97.9)1890(98.1)1583(98.8)
 Yes (n = 199)77(3.1)67(2.1)36(1.9)19(1.2)
Smoking status n (%)<0.001
 Never (n = 5217)1561(63.7)1831(56.3)1014(52.6)811(50.6)
 Former (n = 1974)359(14.7)704(21.7)475(24.7)436(27.2)
 Current (n = 2036)529(21.6)715(22.0)437(22.7)355(22.2)
Physical activity
CharacteristicsInactiveModerately inactiveModerately activeActiveP valuea
Men (n = 5436)
n (%)913(16.8)1737(32.0)1416(26.0)1370(25.2)
Age (years)b55.3 ± 9.052.5 ± 8.551.9 ± 8.550.9 ± 8.8<0.001
Educational level n (%)<0.001
 No schooling (n = 361)70(7.7)103(5.9)97(6.9)91(6.6)
 Primary (n = 1830)315(34.5)506(29.1)490(34.6)519(37.9)
 Secondary (n = 708)114(12.5)249(14.3)196(13.8)149(10.9)
 Vocational/university (n = 2537)414(45.3)879(50.6)633(44.7)611(44.6)
Alcohol consumption n (%)<0.001
 None (n = 420)107(11.7)118(6.8)98(6.9)97(7.1)
 1–≤5 g/day (n = 1030)199(21.8)321(18.5)260(18.4)250(18.2)
 >5–≤10 g/day (n = 748)124(13.6)245(14.1)196(13.8)183(13.4)
 >10–≤40 g/day (n = 2182)327(35.8)716(41.2)577(40.7)562(41.0)
 >40 g/day (n = 1056)156(17.1)337(19.4)285(20.1)278(20.3)
Fruit (g/day)c154.0(216.8)155.2(193.6)153.6(213.9)174.9(230.2)<0.001
Vegetables (g/day)c146.5(156.6)137.5(136.9)151.7(138.7)146.5(148.5)0.091
Body mass index n (%)<0.001
 <25 kg/m2 (n = 1776)249(27.3)556(32.0)477(33.7)494(36.1)
 25–29.9 kg/m2 (n = 2714)460(50.4)893(51.4)701(49.5)660(48.2)
 ≥30 kg/m2 (n = 946)204(22.3)288(16.6)238(16.8)216(15.8)
Total cholesterol n (%)0.004
 <5.2 mmol/L (n = 1498)232(25.4)431(24.8)413(29.2)422(30.8)
 5.2–6.1 mmol/L (n = 2006)335(36.7)667(38.4)523(36.9)481(35.1)
 ≥6.0 mmol/L (n = 1932)346(37.9)639(36.8)480(33.9)467(34.1)
Hypertension n (%)d<0.001
 No (n = 3340)505(55.3)1059(61.0)901(63.6)875(63.9)
 Yes (n = 2096)408(44.7)678(39.0)515(36.4)495(36.1)
History of diabetes n (%)<0.001
 No (n = 5236)858(94.0)1677(96.5)1369(96.7)1332(97.2)
 Yes (n = 200)55(6.0)60(3.5)47(3.3)38(2.8)
Smoking status n (%)<0.001
 Never (n = 1731)234(25.6)573(33.0)468(33.1)456(33.3)
 Former (n = 1964)327(35.8)636(36.6)498(35.2)503(36.7)
 Current (n = 1741)352(38.6)528(30.4)450(31.8)411(30.0)
Women n = 9227
n (%)2449(26.5)3250(35.2)1926(20.9)1602(17.4)
Age (years)b52.4 ± 9.652.1 ± 9.451.3 ± 8.851.5 ± 9.0<0.001
Educational level n (%)<0.001
 No schooling (n = 887)489(20.0)287(8.8)79(4.1)32(2.0)
 Primary (n = 3018)1043(42.6)1016(31.3)518(26.9)441(27.5)
 Secondary (n = 1557)294(12.0)574(17.7)379(19.7)310(19.4)
 Vocational/University (n = 3765)623(25.4)1373(42.2)950(49.3)819(51.1)
Alcohol consumption n (%)<0.001
 None (n = 2018)847(34.6)665(20.5)284(14.7)222(13.9)
 1–≤5 g/day (n = 3364)806(32.9)1240(38.2)745(38.7)573(35.8)
 >5–≤10 g/day (n = 1307)275(11.2)436(13.4)313(16.3)283(17.7)
 >10–≤40 g/day (n = 2298)477(19.5)823(25.3)534(27.7)464(29.0)
 >40 g/day (n = 240)44(1.8)86(2.6)50(2.6)60(3.7)
Fruit (g/day)c250.0(246.1)213.4(211.4)200.9(193.7)216.1(191.5)<0.001
Vegetables (g/day)c178.4(158.1)161.7(133.8)161.3(134.9)154.7(124.7)<0.001
Body mass index n (%)<0.001
 <25 kg/m2 (n = 4629)904(36.9)1666(51.3)1125(58.4)934(58.3)
 25–29.9 kg/m2 (n = 3077)895(36.5)1107(34.1)588(30.5)487(30.4)
 ≥3 kg/m2 (n = 1521)650(26.5)477(14.7)213(11.1)181(11.3)
Total cholesterol n (%)0.142
 <5.2 mmol/L (n = 2588)658(26.9)942(29.0)547(28.4)441(27.5)
 5.2–6.21 mmol/L (n = 3297)875(35.7)1119(34.4)724(37.6)579(36.1)
 ≥6.2 mmol/L (n = 3342)916(37.4)1189(36.6)655(34.0)582(36.3)
Hypertension n (%)d<0.001
 No (n = 6165)1588(64.8)2153(66.2)1372(71.2)1052(65.7)
 Yes (n = 3062)861(35.2)1097(33.8)554(28.8)550(34.3)
History of diabetes n (%)<0.001
 No (n = 9028)2372(96.9)3183(97.9)1890(98.1)1583(98.8)
 Yes (n = 199)77(3.1)67(2.1)36(1.9)19(1.2)
Smoking status n (%)<0.001
 Never (n = 5217)1561(63.7)1831(56.3)1014(52.6)811(50.6)
 Former (n = 1974)359(14.7)704(21.7)475(24.7)436(27.2)
 Current (n = 2036)529(21.6)715(22.0)437(22.7)355(22.2)
a

P values are derived from a Kruskal Wallis or ANOVA test for continuous variables or from a Chi-square test for categorical variables;

b

Values for normally distributed variables are expressed as mean ± standard deviation;

c

Values from non-normally distributed variables are expressed as median (interquartile range);

d

Hypertension definition is based on medical history and/or clinical measurements.

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