Table 2

Management strategy and crude clinical outcome

VariablesNon-cardiac ward (n = 142 876)Cardiac ward (n = 194 279)P-value
Pharmacotherapy
Low molecular weight heparin (%)63 846/120 734 (53%)83 223/167 934 (50%)<0.001
Fondaparinux60 060/121 133 (50%)75 242/168 577 (45%)<0.001
Warfarin (%)8357/120 040 (7%)10 366/166 921 (6%)<0.001
Unfractionated heparin10 643/119 617 (9%)32 930/166 376 (20%)<0.001
Glycoprotein 2b/3a inhibitor (%)2579/122 017 (2%)7426/169 024 (4%)<0.001
IV nitrate13 010/119 981 (11%)24 094/166 887 (14%)<0.001
Furosemide (%)38 875/120 378 (32%)44 599/167 376 (27%)<0.001
Calcium channel blockers (%)23 969/120 179 (20%)33 689/167 133 (20%)0.16
IV beta-blockers (%)971/120 689 (0.8%)2273/167 860 (1.4%)<0.001
MRA (%)8339/119 730 (7%)12 073/165 600 (7%)0.001
Thiazide diuretics (%)5956/119 771 (5%)7730/166 687 (4.6%)<0.001
Aspirin (%)135 989/142 413 (95%)188 631/193 737 (97%)<0.001
P2Y12 inhibitor (%)129 478/142 323 (91%)179 672/193 534 (93%)<0.001
Statins (%)115 283/141 645 (81%)164 792/193 178 (85%)<0.001
ACE inhibitors/ARB (%)110 538/141 607 (78%)161 248/193 311 (83%)<0.001
Beta-blockers (%)110 647/140 980 (78%)161 757/192 558 (84%)<0.001
Management strategy
Radionuclide Study (%)3298/123 456 (2.7%)3961/164 393 (2.4%)<0.001
Exercise test3030/123 897 (2%)7330/168 632 (4%)<0.001
Coronary angiogram (%)80 147/136 934 (59%)144 457/184 895 (78%)<0.001
Percutaneous coronary intervention (%)37 361/104 436 (36%)82 071/157 704 (52%)<0.001
CABG (%)6821/104 436 (7%)12 156/157 704 (8%)<0.001
Revascularisation (CABG/PCI)44 182/104 436 (42%)94 227/157 704 (60%)<0.001
Crude inhospital clinical outcomes
Death (%)8903/142 876 (6.2%)5299/194 279 (2.7%)<0.001
Cardiac mortality (%)6829/142 876 (4.8%)4373/194 279 (2.2%)<0.001
Reinfarction (%)1229/132 239 (0.9%)1572/182 182 (0.9%)0.05
Major bleeding (%)2340/139 507 (1.7%)2396/190 628 (1.3%)<0.001
MACEa (%)9810/142 876 (6.9%)6638/194 279 (3.4%)<0.001
VariablesNon-cardiac ward (n = 142 876)Cardiac ward (n = 194 279)P-value
Pharmacotherapy
Low molecular weight heparin (%)63 846/120 734 (53%)83 223/167 934 (50%)<0.001
Fondaparinux60 060/121 133 (50%)75 242/168 577 (45%)<0.001
Warfarin (%)8357/120 040 (7%)10 366/166 921 (6%)<0.001
Unfractionated heparin10 643/119 617 (9%)32 930/166 376 (20%)<0.001
Glycoprotein 2b/3a inhibitor (%)2579/122 017 (2%)7426/169 024 (4%)<0.001
IV nitrate13 010/119 981 (11%)24 094/166 887 (14%)<0.001
Furosemide (%)38 875/120 378 (32%)44 599/167 376 (27%)<0.001
Calcium channel blockers (%)23 969/120 179 (20%)33 689/167 133 (20%)0.16
IV beta-blockers (%)971/120 689 (0.8%)2273/167 860 (1.4%)<0.001
MRA (%)8339/119 730 (7%)12 073/165 600 (7%)0.001
Thiazide diuretics (%)5956/119 771 (5%)7730/166 687 (4.6%)<0.001
Aspirin (%)135 989/142 413 (95%)188 631/193 737 (97%)<0.001
P2Y12 inhibitor (%)129 478/142 323 (91%)179 672/193 534 (93%)<0.001
Statins (%)115 283/141 645 (81%)164 792/193 178 (85%)<0.001
ACE inhibitors/ARB (%)110 538/141 607 (78%)161 248/193 311 (83%)<0.001
Beta-blockers (%)110 647/140 980 (78%)161 757/192 558 (84%)<0.001
Management strategy
Radionuclide Study (%)3298/123 456 (2.7%)3961/164 393 (2.4%)<0.001
Exercise test3030/123 897 (2%)7330/168 632 (4%)<0.001
Coronary angiogram (%)80 147/136 934 (59%)144 457/184 895 (78%)<0.001
Percutaneous coronary intervention (%)37 361/104 436 (36%)82 071/157 704 (52%)<0.001
CABG (%)6821/104 436 (7%)12 156/157 704 (8%)<0.001
Revascularisation (CABG/PCI)44 182/104 436 (42%)94 227/157 704 (60%)<0.001
Crude inhospital clinical outcomes
Death (%)8903/142 876 (6.2%)5299/194 279 (2.7%)<0.001
Cardiac mortality (%)6829/142 876 (4.8%)4373/194 279 (2.2%)<0.001
Reinfarction (%)1229/132 239 (0.9%)1572/182 182 (0.9%)0.05
Major bleeding (%)2340/139 507 (1.7%)2396/190 628 (1.3%)<0.001
MACEa (%)9810/142 876 (6.9%)6638/194 279 (3.4%)<0.001

ACE, angiotensin converting enzyme; ARB, angiotensin receptor blocker; CABG surgery, coronary artery bypass grafting surgery; IV, intravenous; MACE, major adverse cardiovascular events; MRA, mineralocorticoid receptor antagonist.

aMACE is defined as composite endpoint of inpatient mortality and reinfarction.

Table 2

Management strategy and crude clinical outcome

VariablesNon-cardiac ward (n = 142 876)Cardiac ward (n = 194 279)P-value
Pharmacotherapy
Low molecular weight heparin (%)63 846/120 734 (53%)83 223/167 934 (50%)<0.001
Fondaparinux60 060/121 133 (50%)75 242/168 577 (45%)<0.001
Warfarin (%)8357/120 040 (7%)10 366/166 921 (6%)<0.001
Unfractionated heparin10 643/119 617 (9%)32 930/166 376 (20%)<0.001
Glycoprotein 2b/3a inhibitor (%)2579/122 017 (2%)7426/169 024 (4%)<0.001
IV nitrate13 010/119 981 (11%)24 094/166 887 (14%)<0.001
Furosemide (%)38 875/120 378 (32%)44 599/167 376 (27%)<0.001
Calcium channel blockers (%)23 969/120 179 (20%)33 689/167 133 (20%)0.16
IV beta-blockers (%)971/120 689 (0.8%)2273/167 860 (1.4%)<0.001
MRA (%)8339/119 730 (7%)12 073/165 600 (7%)0.001
Thiazide diuretics (%)5956/119 771 (5%)7730/166 687 (4.6%)<0.001
Aspirin (%)135 989/142 413 (95%)188 631/193 737 (97%)<0.001
P2Y12 inhibitor (%)129 478/142 323 (91%)179 672/193 534 (93%)<0.001
Statins (%)115 283/141 645 (81%)164 792/193 178 (85%)<0.001
ACE inhibitors/ARB (%)110 538/141 607 (78%)161 248/193 311 (83%)<0.001
Beta-blockers (%)110 647/140 980 (78%)161 757/192 558 (84%)<0.001
Management strategy
Radionuclide Study (%)3298/123 456 (2.7%)3961/164 393 (2.4%)<0.001
Exercise test3030/123 897 (2%)7330/168 632 (4%)<0.001
Coronary angiogram (%)80 147/136 934 (59%)144 457/184 895 (78%)<0.001
Percutaneous coronary intervention (%)37 361/104 436 (36%)82 071/157 704 (52%)<0.001
CABG (%)6821/104 436 (7%)12 156/157 704 (8%)<0.001
Revascularisation (CABG/PCI)44 182/104 436 (42%)94 227/157 704 (60%)<0.001
Crude inhospital clinical outcomes
Death (%)8903/142 876 (6.2%)5299/194 279 (2.7%)<0.001
Cardiac mortality (%)6829/142 876 (4.8%)4373/194 279 (2.2%)<0.001
Reinfarction (%)1229/132 239 (0.9%)1572/182 182 (0.9%)0.05
Major bleeding (%)2340/139 507 (1.7%)2396/190 628 (1.3%)<0.001
MACEa (%)9810/142 876 (6.9%)6638/194 279 (3.4%)<0.001
VariablesNon-cardiac ward (n = 142 876)Cardiac ward (n = 194 279)P-value
Pharmacotherapy
Low molecular weight heparin (%)63 846/120 734 (53%)83 223/167 934 (50%)<0.001
Fondaparinux60 060/121 133 (50%)75 242/168 577 (45%)<0.001
Warfarin (%)8357/120 040 (7%)10 366/166 921 (6%)<0.001
Unfractionated heparin10 643/119 617 (9%)32 930/166 376 (20%)<0.001
Glycoprotein 2b/3a inhibitor (%)2579/122 017 (2%)7426/169 024 (4%)<0.001
IV nitrate13 010/119 981 (11%)24 094/166 887 (14%)<0.001
Furosemide (%)38 875/120 378 (32%)44 599/167 376 (27%)<0.001
Calcium channel blockers (%)23 969/120 179 (20%)33 689/167 133 (20%)0.16
IV beta-blockers (%)971/120 689 (0.8%)2273/167 860 (1.4%)<0.001
MRA (%)8339/119 730 (7%)12 073/165 600 (7%)0.001
Thiazide diuretics (%)5956/119 771 (5%)7730/166 687 (4.6%)<0.001
Aspirin (%)135 989/142 413 (95%)188 631/193 737 (97%)<0.001
P2Y12 inhibitor (%)129 478/142 323 (91%)179 672/193 534 (93%)<0.001
Statins (%)115 283/141 645 (81%)164 792/193 178 (85%)<0.001
ACE inhibitors/ARB (%)110 538/141 607 (78%)161 248/193 311 (83%)<0.001
Beta-blockers (%)110 647/140 980 (78%)161 757/192 558 (84%)<0.001
Management strategy
Radionuclide Study (%)3298/123 456 (2.7%)3961/164 393 (2.4%)<0.001
Exercise test3030/123 897 (2%)7330/168 632 (4%)<0.001
Coronary angiogram (%)80 147/136 934 (59%)144 457/184 895 (78%)<0.001
Percutaneous coronary intervention (%)37 361/104 436 (36%)82 071/157 704 (52%)<0.001
CABG (%)6821/104 436 (7%)12 156/157 704 (8%)<0.001
Revascularisation (CABG/PCI)44 182/104 436 (42%)94 227/157 704 (60%)<0.001
Crude inhospital clinical outcomes
Death (%)8903/142 876 (6.2%)5299/194 279 (2.7%)<0.001
Cardiac mortality (%)6829/142 876 (4.8%)4373/194 279 (2.2%)<0.001
Reinfarction (%)1229/132 239 (0.9%)1572/182 182 (0.9%)0.05
Major bleeding (%)2340/139 507 (1.7%)2396/190 628 (1.3%)<0.001
MACEa (%)9810/142 876 (6.9%)6638/194 279 (3.4%)<0.001

ACE, angiotensin converting enzyme; ARB, angiotensin receptor blocker; CABG surgery, coronary artery bypass grafting surgery; IV, intravenous; MACE, major adverse cardiovascular events; MRA, mineralocorticoid receptor antagonist.

aMACE is defined as composite endpoint of inpatient mortality and reinfarction.

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