Table 1 Open in new tab Clinical...

	Non-cardiac ward	Cardiac ward
Age (y)	75 (64–84)	70 (60–80)	<0.001
Women (%)	57 445/142 876 (40%)	63 182/194 279 (33%)	<0.001
Caucasians (%)	122 583/132 589 (92%)	160 472/176 053 (91%)	<0.001
BMI median [IQR]	27 (24–31)	27 (24–31)	<0.001
Killip class
No Heart failure	62 375/85 715 (73%)	105 810/130 951(81%)	<0.001
Basal crepitations	17 659/85 715 (21%)	17 255/130 951 (13%)	<0.001
Pulmonary oedema (%)	5378/85 715 (6.3%)	7226/130 951 (5.5%)	<0.001
Cardiogenic shock (%)	303/85 715 (0.4%)	660/130 951 (0.5%)	<0.001
GRACE score
High-risk GRACE score >140 (%)	67 328/82 775 (81%)	93 206/125 406 (74%)	<0.001
Intermediate-risk GRACE score 109–140 (%)	12 651/82 775 (15%)	25 259/125 406 (20%)	<0.001
Low-risk GRACE score <109 (%)	2796/82 775 (3%)	6941/125 406 (6%)	<0.001
Other clinical characteristics
ECG ST changes (%)	105 930/139 390 (76%)	147 775/188 843 (78%)	<0.001
Previous smoker (%)	51 288/134 378 (38%)	69 409/186 830 (37%)	<0.001
Current smoker (%)	26 037/134 378 (19%)	44 345/186 830 (24%)	<0.001
Chronic renal failure (%)	13 743/132 773 (10%)	14 710/184 215 (8%)	<0.001
Prior PCI (%)	17 088/132 799 (13%)	30 115/184 234 (16%)	<0.001
Diabetes (%)	37 949/140 728 (27%)	50 300/191 585 (26%)	<0.001
CCF (%)	12 974/132 800 (10%)	12 892/184 199 (7%)	<0.001
Hypercholesterolemia (%)	43 238/132 019 (33%)	73 252/182 804 (40%)	<0.001
Previous MI (%)	42 651/133 758 (32%)	56 168/185 925 (30%)	<0.001
Angina (%)	44 210/133 000 (33%)	57 864/183 600 (32%)	<0.001
Cerebrovascular disease (%)	16 080/133 081 (12%)	16 467/184 390 (9%)	<0.001
Peripheral vascular disease (%)	7332/132 161 (6%)	10 288/183 789 (6%)	0.54
Hypertension (%)	74 359/134 226 (55%)	104 478/185 402 (56%)	<0.001
Asthma/COPD (%)	25 864/133 287 (19%)	30 187/184 499 (16%)	<0.001
Family history of CAD (%)	26 043/105 843 (25%)	50 835/161 511 (31%)	<0.001
Heart rate, bpm, median (IQR)	79 (67–93)	76 (65–90)	<0.001
Systolic blood pressure, median (IQR)	140 (121–158)	140 (122–158)	0.32
Moderate LVSD	17 159/109 898 (16%)	29 240/149 150 (20%)	<0.001
Severe LVSD	7521/109 898 (7%)	11 587/149 150 (8%)	<0.001
Admission under cardiologist during first 24 h (%)	21 512/137 246 (16%)	146 681/188 115 (78%)	<0.001
Cardiac arrest (%)	3447/140 174 (2.5%)	4454/189 140 (2.4%)	0.05
Previous CABG (%)	12 420/133 037 (9%)	18 279/184 379 (10%)	<0.001

Non-cardiac ward

Cardiac ward

Variables

(n = 142 876)

(n = 194 279)

P-value

Age (y)

75 (64–84)

70 (60–80)

<0.001

Women (%)

57 445/142 876 (40%)

63 182/194 279 (33%)

<0.001

Caucasians (%)

122 583/132 589 (92%)

160 472/176 053 (91%)

<0.001

BMI median [IQR]

27 (24–31)

<0.001

Killip class

No Heart failure

62 375/85 715 (73%)

105 810/130 951(81%)

<0.001

Basal crepitations

17 659/85 715 (21%)

17 255/130 951 (13%)

<0.001

Pulmonary oedema (%)

5378/85 715 (6.3%)

7226/130 951 (5.5%)

<0.001

Cardiogenic shock (%)

303/85 715 (0.4%)

660/130 951 (0.5%)

<0.001

GRACE score

High-risk GRACE score >140 (%)

67 328/82 775 (81%)

93 206/125 406 (74%)

<0.001

Intermediate-risk GRACE score 109–140 (%)

12 651/82 775 (15%)

25 259/125 406 (20%)

<0.001

Low-risk GRACE score <109 (%)

2796/82 775 (3%)

6941/125 406 (6%)

<0.001

Other clinical characteristics

ECG ST changes (%)

105 930/139 390 (76%)

147 775/188 843 (78%)

<0.001

Previous smoker (%)

51 288/134 378 (38%)

69 409/186 830 (37%)

<0.001

Current smoker (%)

26 037/134 378 (19%)

44 345/186 830 (24%)

<0.001

Chronic renal failure (%)

13 743/132 773 (10%)

14 710/184 215 (8%)

<0.001

Prior PCI (%)

17 088/132 799 (13%)

30 115/184 234 (16%)

<0.001

Diabetes (%)

37 949/140 728 (27%)

50 300/191 585 (26%)

<0.001

CCF (%)

12 974/132 800 (10%)

12 892/184 199 (7%)

<0.001

Hypercholesterolemia (%)

43 238/132 019 (33%)

73 252/182 804 (40%)

<0.001

Previous MI (%)

42 651/133 758 (32%)

56 168/185 925 (30%)

<0.001

Angina (%)

44 210/133 000 (33%)

57 864/183 600 (32%)

<0.001

Cerebrovascular disease (%)

16 080/133 081 (12%)

16 467/184 390 (9%)

<0.001

Peripheral vascular disease (%)

7332/132 161 (6%)

10 288/183 789 (6%)

0.54

Hypertension (%)

74 359/134 226 (55%)

104 478/185 402 (56%)

<0.001

Asthma/COPD (%)

25 864/133 287 (19%)

30 187/184 499 (16%)

<0.001

Family history of CAD (%)

26 043/105 843 (25%)

50 835/161 511 (31%)

<0.001

Heart rate, bpm, median (IQR)

79 (67–93)

76 (65–90)

<0.001

Systolic blood pressure, median (IQR)

140 (121–158)

140 (122–158)

0.32

Moderate LVSD

17 159/109 898 (16%)

29 240/149 150 (20%)

<0.001

Severe LVSD

7521/109 898 (7%)

11 587/149 150 (8%)

<0.001

Admission under cardiologist during first 24 h (%)

21 512/137 246 (16%)

146 681/188 115 (78%)

<0.001

Cardiac arrest (%)

3447/140 174 (2.5%)

4454/189 140 (2.4%)

0.05

Previous CABG (%)

12 420/133 037 (9%)

18 279/184 379 (10%)

<0.001

	Non-cardiac ward	Cardiac ward
Age (y)	75 (64–84)	70 (60–80)	<0.001
Women (%)	57 445/142 876 (40%)	63 182/194 279 (33%)	<0.001
Caucasians (%)	122 583/132 589 (92%)	160 472/176 053 (91%)	<0.001
BMI median [IQR]	27 (24–31)	27 (24–31)	<0.001
Killip class
No Heart failure	62 375/85 715 (73%)	105 810/130 951(81%)	<0.001
Basal crepitations	17 659/85 715 (21%)	17 255/130 951 (13%)	<0.001
Pulmonary oedema (%)	5378/85 715 (6.3%)	7226/130 951 (5.5%)	<0.001
Cardiogenic shock (%)	303/85 715 (0.4%)	660/130 951 (0.5%)	<0.001
GRACE score
High-risk GRACE score >140 (%)	67 328/82 775 (81%)	93 206/125 406 (74%)	<0.001
Intermediate-risk GRACE score 109–140 (%)	12 651/82 775 (15%)	25 259/125 406 (20%)	<0.001
Low-risk GRACE score <109 (%)	2796/82 775 (3%)	6941/125 406 (6%)	<0.001
Other clinical characteristics
ECG ST changes (%)	105 930/139 390 (76%)	147 775/188 843 (78%)	<0.001
Previous smoker (%)	51 288/134 378 (38%)	69 409/186 830 (37%)	<0.001
Current smoker (%)	26 037/134 378 (19%)	44 345/186 830 (24%)	<0.001
Chronic renal failure (%)	13 743/132 773 (10%)	14 710/184 215 (8%)	<0.001
Prior PCI (%)	17 088/132 799 (13%)	30 115/184 234 (16%)	<0.001
Diabetes (%)	37 949/140 728 (27%)	50 300/191 585 (26%)	<0.001
CCF (%)	12 974/132 800 (10%)	12 892/184 199 (7%)	<0.001
Hypercholesterolemia (%)	43 238/132 019 (33%)	73 252/182 804 (40%)	<0.001
Previous MI (%)	42 651/133 758 (32%)	56 168/185 925 (30%)	<0.001
Angina (%)	44 210/133 000 (33%)	57 864/183 600 (32%)	<0.001
Cerebrovascular disease (%)	16 080/133 081 (12%)	16 467/184 390 (9%)	<0.001
Peripheral vascular disease (%)	7332/132 161 (6%)	10 288/183 789 (6%)	0.54
Hypertension (%)	74 359/134 226 (55%)	104 478/185 402 (56%)	<0.001
Asthma/COPD (%)	25 864/133 287 (19%)	30 187/184 499 (16%)	<0.001
Family history of CAD (%)	26 043/105 843 (25%)	50 835/161 511 (31%)	<0.001
Heart rate, bpm, median (IQR)	79 (67–93)	76 (65–90)	<0.001
Systolic blood pressure, median (IQR)	140 (121–158)	140 (122–158)	0.32
Moderate LVSD	17 159/109 898 (16%)	29 240/149 150 (20%)	<0.001
Severe LVSD	7521/109 898 (7%)	11 587/149 150 (8%)	<0.001
Admission under cardiologist during first 24 h (%)	21 512/137 246 (16%)	146 681/188 115 (78%)	<0.001
Cardiac arrest (%)	3447/140 174 (2.5%)	4454/189 140 (2.4%)	0.05
Previous CABG (%)	12 420/133 037 (9%)	18 279/184 379 (10%)	<0.001

Table 1

Open in new tab

Clinical characteristics

	Non-cardiac ward	Cardiac ward
Variables	(n = 142 876)	(n = 194 279)	P-value
Age (y)	75 (64–84)	70 (60–80)	<0.001
Women (%)	57 445/142 876 (40%)	63 182/194 279 (33%)	<0.001
Caucasians (%)	122 583/132 589 (92%)	160 472/176 053 (91%)	<0.001
BMI median [IQR]	27 (24–31)	27 (24–31)	<0.001
Killip class
No Heart failure	62 375/85 715 (73%)	105 810/130 951(81%)	<0.001
Basal crepitations	17 659/85 715 (21%)	17 255/130 951 (13%)	<0.001
Pulmonary oedema (%)	5378/85 715 (6.3%)	7226/130 951 (5.5%)	<0.001
Cardiogenic shock (%)	303/85 715 (0.4%)	660/130 951 (0.5%)	<0.001
GRACE score
High-risk GRACE score >140 (%)	67 328/82 775 (81%)	93 206/125 406 (74%)	<0.001
Intermediate-risk GRACE score 109–140 (%)	12 651/82 775 (15%)	25 259/125 406 (20%)	<0.001
Low-risk GRACE score <109 (%)	2796/82 775 (3%)	6941/125 406 (6%)	<0.001
Other clinical characteristics
ECG ST changes (%)	105 930/139 390 (76%)	147 775/188 843 (78%)	<0.001
Previous smoker (%)	51 288/134 378 (38%)	69 409/186 830 (37%)	<0.001
Current smoker (%)	26 037/134 378 (19%)	44 345/186 830 (24%)	<0.001
Chronic renal failure (%)	13 743/132 773 (10%)	14 710/184 215 (8%)	<0.001
Prior PCI (%)	17 088/132 799 (13%)	30 115/184 234 (16%)	<0.001
Diabetes (%)	37 949/140 728 (27%)	50 300/191 585 (26%)	<0.001
CCF (%)	12 974/132 800 (10%)	12 892/184 199 (7%)	<0.001
Hypercholesterolemia (%)	43 238/132 019 (33%)	73 252/182 804 (40%)	<0.001
Previous MI (%)	42 651/133 758 (32%)	56 168/185 925 (30%)	<0.001
Angina (%)	44 210/133 000 (33%)	57 864/183 600 (32%)	<0.001
Cerebrovascular disease (%)	16 080/133 081 (12%)	16 467/184 390 (9%)	<0.001
Peripheral vascular disease (%)	7332/132 161 (6%)	10 288/183 789 (6%)	0.54
Hypertension (%)	74 359/134 226 (55%)	104 478/185 402 (56%)	<0.001
Asthma/COPD (%)	25 864/133 287 (19%)	30 187/184 499 (16%)	<0.001
Family history of CAD (%)	26 043/105 843 (25%)	50 835/161 511 (31%)	<0.001
Heart rate, bpm, median (IQR)	79 (67–93)	76 (65–90)	<0.001
Systolic blood pressure, median (IQR)	140 (121–158)	140 (122–158)	0.32
Moderate LVSD	17 159/109 898 (16%)	29 240/149 150 (20%)	<0.001
Severe LVSD	7521/109 898 (7%)	11 587/149 150 (8%)	<0.001
Admission under cardiologist during first 24 h (%)	21 512/137 246 (16%)	146 681/188 115 (78%)	<0.001
Cardiac arrest (%)	3447/140 174 (2.5%)	4454/189 140 (2.4%)	0.05
Previous CABG (%)	12 420/133 037 (9%)	18 279/184 379 (10%)	<0.001

	Non-cardiac ward	Cardiac ward
Variables	(n = 142 876)	(n = 194 279)	P-value
Age (y)	75 (64–84)	70 (60–80)	<0.001
Women (%)	57 445/142 876 (40%)	63 182/194 279 (33%)	<0.001
Caucasians (%)	122 583/132 589 (92%)	160 472/176 053 (91%)	<0.001
BMI median [IQR]	27 (24–31)	27 (24–31)	<0.001
Killip class
No Heart failure	62 375/85 715 (73%)	105 810/130 951(81%)	<0.001
Basal crepitations	17 659/85 715 (21%)	17 255/130 951 (13%)	<0.001
Pulmonary oedema (%)	5378/85 715 (6.3%)	7226/130 951 (5.5%)	<0.001
Cardiogenic shock (%)	303/85 715 (0.4%)	660/130 951 (0.5%)	<0.001
GRACE score
High-risk GRACE score >140 (%)	67 328/82 775 (81%)	93 206/125 406 (74%)	<0.001
Intermediate-risk GRACE score 109–140 (%)	12 651/82 775 (15%)	25 259/125 406 (20%)	<0.001
Low-risk GRACE score <109 (%)	2796/82 775 (3%)	6941/125 406 (6%)	<0.001
Other clinical characteristics
ECG ST changes (%)	105 930/139 390 (76%)	147 775/188 843 (78%)	<0.001
Previous smoker (%)	51 288/134 378 (38%)	69 409/186 830 (37%)	<0.001
Current smoker (%)	26 037/134 378 (19%)	44 345/186 830 (24%)	<0.001
Chronic renal failure (%)	13 743/132 773 (10%)	14 710/184 215 (8%)	<0.001
Prior PCI (%)	17 088/132 799 (13%)	30 115/184 234 (16%)	<0.001
Diabetes (%)	37 949/140 728 (27%)	50 300/191 585 (26%)	<0.001
CCF (%)	12 974/132 800 (10%)	12 892/184 199 (7%)	<0.001
Hypercholesterolemia (%)	43 238/132 019 (33%)	73 252/182 804 (40%)	<0.001
Previous MI (%)	42 651/133 758 (32%)	56 168/185 925 (30%)	<0.001
Angina (%)	44 210/133 000 (33%)	57 864/183 600 (32%)	<0.001
Cerebrovascular disease (%)	16 080/133 081 (12%)	16 467/184 390 (9%)	<0.001
Peripheral vascular disease (%)	7332/132 161 (6%)	10 288/183 789 (6%)	0.54
Hypertension (%)	74 359/134 226 (55%)	104 478/185 402 (56%)	<0.001
Asthma/COPD (%)	25 864/133 287 (19%)	30 187/184 499 (16%)	<0.001
Family history of CAD (%)	26 043/105 843 (25%)	50 835/161 511 (31%)	<0.001
Heart rate, bpm, median (IQR)	79 (67–93)	76 (65–90)	<0.001
Systolic blood pressure, median (IQR)	140 (121–158)	140 (122–158)	0.32
Moderate LVSD	17 159/109 898 (16%)	29 240/149 150 (20%)	<0.001
Severe LVSD	7521/109 898 (7%)	11 587/149 150 (8%)	<0.001
Admission under cardiologist during first 24 h (%)	21 512/137 246 (16%)	146 681/188 115 (78%)	<0.001
Cardiac arrest (%)	3447/140 174 (2.5%)	4454/189 140 (2.4%)	0.05
Previous CABG (%)	12 420/133 037 (9%)	18 279/184 379 (10%)	<0.001

BMI, body mass index; CABG surgery, coronary artery bypass grafting surgery; CAD, coronary artery disease; CCF, congestive cardiac failure; COPD, chronic obstructive pulmonary disease; ECG, electrocardiograph; EF, ejection fraction; GRACE, Global Registry of Acute Coronary Events; IQR, interquartile range; LVSD, left ventricular systolic dysfunction; MI, myocardial infarction; PCI, percutaneous coronary intervention.

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