Clinical risk factors for prolonged mechanical ventilation for >14 days after lung transplantation according to multivariable analysis
. | Multivariable model . | ||||||
---|---|---|---|---|---|---|---|
. | Adjusted regression model . | Backward stepwise regression model . | |||||
Variable . | Odds ratio for PMV . | 95% confidence interval . | P-Value . | VIF . | Odds ratio for PMV . | 95% confidence interval . | P-Value . |
Recipient sex | |||||||
Female | 1 | [Reference] | |||||
Male | 0.6 | 0.1–3.0 | 0.513 | 1.2 | |||
Transplant type | |||||||
Bilateral | 1 | [Reference] | |||||
Single | 0.8 | 0.1–6.7 | 0.824 | 2.2 | |||
Thoracic mediastinal-occupying ratio (%) | |||||||
≤40 | 1 | [Reference] | |||||
>40 | 7.3 | 1.3–40.1 | 0.023 | 1.0 | 7.2 | 1.3–38.9 | 0.021 |
Total ischaemic time per hour | 1.1 | 0.6–2.2 | 0.672 | 2.1 | |||
ECMO use | 6.2 | 0.6–63.8 | 0.127 | 1.9 | 8.2 | 1.1–59.9 | 0.037 |
Reoperation within 14 days after CLT | 5.5 | 0.8–39.5 | 0.087 | 1.8 | 6.7 | 0.8–39.5 | 0.026 |
. | Multivariable model . | ||||||
---|---|---|---|---|---|---|---|
. | Adjusted regression model . | Backward stepwise regression model . | |||||
Variable . | Odds ratio for PMV . | 95% confidence interval . | P-Value . | VIF . | Odds ratio for PMV . | 95% confidence interval . | P-Value . |
Recipient sex | |||||||
Female | 1 | [Reference] | |||||
Male | 0.6 | 0.1–3.0 | 0.513 | 1.2 | |||
Transplant type | |||||||
Bilateral | 1 | [Reference] | |||||
Single | 0.8 | 0.1–6.7 | 0.824 | 2.2 | |||
Thoracic mediastinal-occupying ratio (%) | |||||||
≤40 | 1 | [Reference] | |||||
>40 | 7.3 | 1.3–40.1 | 0.023 | 1.0 | 7.2 | 1.3–38.9 | 0.021 |
Total ischaemic time per hour | 1.1 | 0.6–2.2 | 0.672 | 2.1 | |||
ECMO use | 6.2 | 0.6–63.8 | 0.127 | 1.9 | 8.2 | 1.1–59.9 | 0.037 |
Reoperation within 14 days after CLT | 5.5 | 0.8–39.5 | 0.087 | 1.8 | 6.7 | 0.8–39.5 | 0.026 |
CLT: cadaveric lung transplantation; ECMO: extracorporeal membrane oxygenation; PMV: prolonged mechanical ventilation; VIF: variance inflation factor.
Clinical risk factors for prolonged mechanical ventilation for >14 days after lung transplantation according to multivariable analysis
. | Multivariable model . | ||||||
---|---|---|---|---|---|---|---|
. | Adjusted regression model . | Backward stepwise regression model . | |||||
Variable . | Odds ratio for PMV . | 95% confidence interval . | P-Value . | VIF . | Odds ratio for PMV . | 95% confidence interval . | P-Value . |
Recipient sex | |||||||
Female | 1 | [Reference] | |||||
Male | 0.6 | 0.1–3.0 | 0.513 | 1.2 | |||
Transplant type | |||||||
Bilateral | 1 | [Reference] | |||||
Single | 0.8 | 0.1–6.7 | 0.824 | 2.2 | |||
Thoracic mediastinal-occupying ratio (%) | |||||||
≤40 | 1 | [Reference] | |||||
>40 | 7.3 | 1.3–40.1 | 0.023 | 1.0 | 7.2 | 1.3–38.9 | 0.021 |
Total ischaemic time per hour | 1.1 | 0.6–2.2 | 0.672 | 2.1 | |||
ECMO use | 6.2 | 0.6–63.8 | 0.127 | 1.9 | 8.2 | 1.1–59.9 | 0.037 |
Reoperation within 14 days after CLT | 5.5 | 0.8–39.5 | 0.087 | 1.8 | 6.7 | 0.8–39.5 | 0.026 |
. | Multivariable model . | ||||||
---|---|---|---|---|---|---|---|
. | Adjusted regression model . | Backward stepwise regression model . | |||||
Variable . | Odds ratio for PMV . | 95% confidence interval . | P-Value . | VIF . | Odds ratio for PMV . | 95% confidence interval . | P-Value . |
Recipient sex | |||||||
Female | 1 | [Reference] | |||||
Male | 0.6 | 0.1–3.0 | 0.513 | 1.2 | |||
Transplant type | |||||||
Bilateral | 1 | [Reference] | |||||
Single | 0.8 | 0.1–6.7 | 0.824 | 2.2 | |||
Thoracic mediastinal-occupying ratio (%) | |||||||
≤40 | 1 | [Reference] | |||||
>40 | 7.3 | 1.3–40.1 | 0.023 | 1.0 | 7.2 | 1.3–38.9 | 0.021 |
Total ischaemic time per hour | 1.1 | 0.6–2.2 | 0.672 | 2.1 | |||
ECMO use | 6.2 | 0.6–63.8 | 0.127 | 1.9 | 8.2 | 1.1–59.9 | 0.037 |
Reoperation within 14 days after CLT | 5.5 | 0.8–39.5 | 0.087 | 1.8 | 6.7 | 0.8–39.5 | 0.026 |
CLT: cadaveric lung transplantation; ECMO: extracorporeal membrane oxygenation; PMV: prolonged mechanical ventilation; VIF: variance inflation factor.
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