Table 1

Definitions of cells based on their differentiation potencies

PotencyCell type/locationDefinitionReference
Totipotent stem cellZygote and cells at morula stageCapable of giving rise to any cell type, or a complete embryo and placenta54
Pluripotent stem cellCells of inner mass of blastocyst and induced pluripotent stem cellsCapable of giving rise to any cell type, or a complete embryo58
Multipotent stem cellAdult stem cells, haematopoietic stem cells, mesenchymal stem cells, cord blood stem cells, etc.Capable of developing into >1 cell type but more limited than pluripotent (usually can give rise to 1–2 germ layers)6,7
Tissue-specific stem cellSomatic stem cellsTypically, can generate different cell types for the specific tissue or organ in which they live. They can be tri- bi- or uni-potent depending on the organ or tissue42
Progenitor cellEndothelial progenitor cells, satellite cells, pancreatic progenitor cells, etc.More differentiated than stem cells and committed in differentiate into cells of the organ of origin; can only replicate a limited number of times42
PotencyCell type/locationDefinitionReference
Totipotent stem cellZygote and cells at morula stageCapable of giving rise to any cell type, or a complete embryo and placenta54
Pluripotent stem cellCells of inner mass of blastocyst and induced pluripotent stem cellsCapable of giving rise to any cell type, or a complete embryo58
Multipotent stem cellAdult stem cells, haematopoietic stem cells, mesenchymal stem cells, cord blood stem cells, etc.Capable of developing into >1 cell type but more limited than pluripotent (usually can give rise to 1–2 germ layers)6,7
Tissue-specific stem cellSomatic stem cellsTypically, can generate different cell types for the specific tissue or organ in which they live. They can be tri- bi- or uni-potent depending on the organ or tissue42
Progenitor cellEndothelial progenitor cells, satellite cells, pancreatic progenitor cells, etc.More differentiated than stem cells and committed in differentiate into cells of the organ of origin; can only replicate a limited number of times42
Table 1

Definitions of cells based on their differentiation potencies

PotencyCell type/locationDefinitionReference
Totipotent stem cellZygote and cells at morula stageCapable of giving rise to any cell type, or a complete embryo and placenta54
Pluripotent stem cellCells of inner mass of blastocyst and induced pluripotent stem cellsCapable of giving rise to any cell type, or a complete embryo58
Multipotent stem cellAdult stem cells, haematopoietic stem cells, mesenchymal stem cells, cord blood stem cells, etc.Capable of developing into >1 cell type but more limited than pluripotent (usually can give rise to 1–2 germ layers)6,7
Tissue-specific stem cellSomatic stem cellsTypically, can generate different cell types for the specific tissue or organ in which they live. They can be tri- bi- or uni-potent depending on the organ or tissue42
Progenitor cellEndothelial progenitor cells, satellite cells, pancreatic progenitor cells, etc.More differentiated than stem cells and committed in differentiate into cells of the organ of origin; can only replicate a limited number of times42
PotencyCell type/locationDefinitionReference
Totipotent stem cellZygote and cells at morula stageCapable of giving rise to any cell type, or a complete embryo and placenta54
Pluripotent stem cellCells of inner mass of blastocyst and induced pluripotent stem cellsCapable of giving rise to any cell type, or a complete embryo58
Multipotent stem cellAdult stem cells, haematopoietic stem cells, mesenchymal stem cells, cord blood stem cells, etc.Capable of developing into >1 cell type but more limited than pluripotent (usually can give rise to 1–2 germ layers)6,7
Tissue-specific stem cellSomatic stem cellsTypically, can generate different cell types for the specific tissue or organ in which they live. They can be tri- bi- or uni-potent depending on the organ or tissue42
Progenitor cellEndothelial progenitor cells, satellite cells, pancreatic progenitor cells, etc.More differentiated than stem cells and committed in differentiate into cells of the organ of origin; can only replicate a limited number of times42
Close
This Feature Is Available To Subscribers Only

Sign In or Create an Account

Close

This PDF is available to Subscribers Only

View Article Abstract & Purchase Options

For full access to this pdf, sign in to an existing account, or purchase an annual subscription.

Close