| . | CRRT . | IRRT . | Reference . |
|---|---|---|---|
| ICU stay | |||
| ICU LoS (days) | 12 | 12 | [13] |
| RRT duration (days) | 7 | 7 | [13] |
| Switch from CRRT to IRRT (%) | 30 | — | Assumption |
| Survival (all cause death) | |||
| Discharged alive from ICU (%) | 60.0 | 60.0 | [11, 12] |
| Alive at 60 days (%) | 46.0 | 46.0 | [11,12] |
| Alive at 180 days (%) | 37.0 | 37.0 | [13] |
| DD among AKI survivorsa | |||
| DD at 90 days (%) | 16.4 | 20.8 | [7] |
| DD at 3 years (%) | 21.7 | 26.6 | [7] |
| Cost of implementing RRT | |||
| Acute RRT cost/day | $858 | $226 | [14, 15] |
| Health utilities | |||
| ICU stay | 0.13 | 0.13 | [16] |
| DI | 0.84 | 0.84 | [17] |
| DD | 0.62 | 0.62 | [17] |
| Healthcare costs | |||
| DI cost/day | $31 | $31 | [5] |
| DD cost/day | $211 | $211 | [5] |
| . | CRRT . | IRRT . | Reference . |
|---|---|---|---|
| ICU stay | |||
| ICU LoS (days) | 12 | 12 | [13] |
| RRT duration (days) | 7 | 7 | [13] |
| Switch from CRRT to IRRT (%) | 30 | — | Assumption |
| Survival (all cause death) | |||
| Discharged alive from ICU (%) | 60.0 | 60.0 | [11, 12] |
| Alive at 60 days (%) | 46.0 | 46.0 | [11,12] |
| Alive at 180 days (%) | 37.0 | 37.0 | [13] |
| DD among AKI survivorsa | |||
| DD at 90 days (%) | 16.4 | 20.8 | [7] |
| DD at 3 years (%) | 21.7 | 26.6 | [7] |
| Cost of implementing RRT | |||
| Acute RRT cost/day | $858 | $226 | [14, 15] |
| Health utilities | |||
| ICU stay | 0.13 | 0.13 | [16] |
| DI | 0.84 | 0.84 | [17] |
| DD | 0.62 | 0.62 | [17] |
| Healthcare costs | |||
| DI cost/day | $31 | $31 | [5] |
| DD cost/day | $211 | $211 | [5] |
LoS, length of stay; ICU, intensive care unit; CRRT/IRRT, continuous/intermittent renal replacement therapy; DI, dialysis independence; DD, dialysis dependence.
aThis corresponds to a risk ratio of ∼0.80 for the base case (16.4/20.8% = 0.79 and 21.7/26.6% = 0.82).
| . | CRRT . | IRRT . | Reference . |
|---|---|---|---|
| ICU stay | |||
| ICU LoS (days) | 12 | 12 | [13] |
| RRT duration (days) | 7 | 7 | [13] |
| Switch from CRRT to IRRT (%) | 30 | — | Assumption |
| Survival (all cause death) | |||
| Discharged alive from ICU (%) | 60.0 | 60.0 | [11, 12] |
| Alive at 60 days (%) | 46.0 | 46.0 | [11,12] |
| Alive at 180 days (%) | 37.0 | 37.0 | [13] |
| DD among AKI survivorsa | |||
| DD at 90 days (%) | 16.4 | 20.8 | [7] |
| DD at 3 years (%) | 21.7 | 26.6 | [7] |
| Cost of implementing RRT | |||
| Acute RRT cost/day | $858 | $226 | [14, 15] |
| Health utilities | |||
| ICU stay | 0.13 | 0.13 | [16] |
| DI | 0.84 | 0.84 | [17] |
| DD | 0.62 | 0.62 | [17] |
| Healthcare costs | |||
| DI cost/day | $31 | $31 | [5] |
| DD cost/day | $211 | $211 | [5] |
| . | CRRT . | IRRT . | Reference . |
|---|---|---|---|
| ICU stay | |||
| ICU LoS (days) | 12 | 12 | [13] |
| RRT duration (days) | 7 | 7 | [13] |
| Switch from CRRT to IRRT (%) | 30 | — | Assumption |
| Survival (all cause death) | |||
| Discharged alive from ICU (%) | 60.0 | 60.0 | [11, 12] |
| Alive at 60 days (%) | 46.0 | 46.0 | [11,12] |
| Alive at 180 days (%) | 37.0 | 37.0 | [13] |
| DD among AKI survivorsa | |||
| DD at 90 days (%) | 16.4 | 20.8 | [7] |
| DD at 3 years (%) | 21.7 | 26.6 | [7] |
| Cost of implementing RRT | |||
| Acute RRT cost/day | $858 | $226 | [14, 15] |
| Health utilities | |||
| ICU stay | 0.13 | 0.13 | [16] |
| DI | 0.84 | 0.84 | [17] |
| DD | 0.62 | 0.62 | [17] |
| Healthcare costs | |||
| DI cost/day | $31 | $31 | [5] |
| DD cost/day | $211 | $211 | [5] |
LoS, length of stay; ICU, intensive care unit; CRRT/IRRT, continuous/intermittent renal replacement therapy; DI, dialysis independence; DD, dialysis dependence.
aThis corresponds to a risk ratio of ∼0.80 for the base case (16.4/20.8% = 0.79 and 21.7/26.6% = 0.82).
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