AUC with a 95% CI in the prediction of GDM using maternal characteristics and metabolites
| . | AUC (95% CI) . | . |
|---|---|---|
| Predictors . | 20 wkGA (n = 469) . | 28 wkGA (n = 466) . |
| Maternal BMI | 0.65 (0.60-0.70) | 0.64 (0.58-0.69) |
| Maternal age | 0.61 (0.56-0.66) | 0.63 (0.58-0.68) |
| Maternal BMI and age | 0.69 (0.64-0.74) | 0.69 (0.63-0.74) |
| 4-metabolite ratio | 0.72 (0.67-0.77) | 0.75 (0.71-0.80) |
| 4-metabolite model | 0.74 (0.70-0.79) | 0.80 (0.76-0.84) |
| 4-metabolite ratio, maternal age, and BMI | 0.75 (0.70-0.79) | 0.78 (0.73-0.82) |
| 4 metabolites, maternal age, and BMI | 0.76 (0.72-0.81) | 0.82 (0.78-0.86) |
| . | AUC (95% CI) . | . |
|---|---|---|
| Predictors . | 20 wkGA (n = 469) . | 28 wkGA (n = 466) . |
| Maternal BMI | 0.65 (0.60-0.70) | 0.64 (0.58-0.69) |
| Maternal age | 0.61 (0.56-0.66) | 0.63 (0.58-0.68) |
| Maternal BMI and age | 0.69 (0.64-0.74) | 0.69 (0.63-0.74) |
| 4-metabolite ratio | 0.72 (0.67-0.77) | 0.75 (0.71-0.80) |
| 4-metabolite model | 0.74 (0.70-0.79) | 0.80 (0.76-0.84) |
| 4-metabolite ratio, maternal age, and BMI | 0.75 (0.70-0.79) | 0.78 (0.73-0.82) |
| 4 metabolites, maternal age, and BMI | 0.76 (0.72-0.81) | 0.82 (0.78-0.86) |
The number of women in the analyses at 20 and 28 wkGA are 469 (171 gestational diabetes mellitus cases and 298 controls) and 466 (171 gestational diabetes mellitus cases and 295 controls), respectively. Maternal BMI and age were recorded at 12 wkGA, and the number of women included in the analysis of maternal characteristics was determined by the availability of metabolite data at 20 and 28 wkGA.
Abbreviations: AUC, area under the receiver operating characteristic curve; BMI, body mass index; wkGA, weeks of gestational age.
AUC with a 95% CI in the prediction of GDM using maternal characteristics and metabolites
| . | AUC (95% CI) . | . |
|---|---|---|
| Predictors . | 20 wkGA (n = 469) . | 28 wkGA (n = 466) . |
| Maternal BMI | 0.65 (0.60-0.70) | 0.64 (0.58-0.69) |
| Maternal age | 0.61 (0.56-0.66) | 0.63 (0.58-0.68) |
| Maternal BMI and age | 0.69 (0.64-0.74) | 0.69 (0.63-0.74) |
| 4-metabolite ratio | 0.72 (0.67-0.77) | 0.75 (0.71-0.80) |
| 4-metabolite model | 0.74 (0.70-0.79) | 0.80 (0.76-0.84) |
| 4-metabolite ratio, maternal age, and BMI | 0.75 (0.70-0.79) | 0.78 (0.73-0.82) |
| 4 metabolites, maternal age, and BMI | 0.76 (0.72-0.81) | 0.82 (0.78-0.86) |
| . | AUC (95% CI) . | . |
|---|---|---|
| Predictors . | 20 wkGA (n = 469) . | 28 wkGA (n = 466) . |
| Maternal BMI | 0.65 (0.60-0.70) | 0.64 (0.58-0.69) |
| Maternal age | 0.61 (0.56-0.66) | 0.63 (0.58-0.68) |
| Maternal BMI and age | 0.69 (0.64-0.74) | 0.69 (0.63-0.74) |
| 4-metabolite ratio | 0.72 (0.67-0.77) | 0.75 (0.71-0.80) |
| 4-metabolite model | 0.74 (0.70-0.79) | 0.80 (0.76-0.84) |
| 4-metabolite ratio, maternal age, and BMI | 0.75 (0.70-0.79) | 0.78 (0.73-0.82) |
| 4 metabolites, maternal age, and BMI | 0.76 (0.72-0.81) | 0.82 (0.78-0.86) |
The number of women in the analyses at 20 and 28 wkGA are 469 (171 gestational diabetes mellitus cases and 298 controls) and 466 (171 gestational diabetes mellitus cases and 295 controls), respectively. Maternal BMI and age were recorded at 12 wkGA, and the number of women included in the analysis of maternal characteristics was determined by the availability of metabolite data at 20 and 28 wkGA.
Abbreviations: AUC, area under the receiver operating characteristic curve; BMI, body mass index; wkGA, weeks of gestational age.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
