Adjusted Intrafamilial Correlation Coefficients From the Familial Aggregation Analysis
Variable . | ICT Positivity . | ICT Intensity . | Microfilaremia Positivity . | Microfilarial Density . | ||
---|---|---|---|---|---|---|
Value . | P Value . | Value . | P Value . | |||
1st degree | 0.03 | −0.09 | 0.43 | <.01 | 0.37 | <.05 |
Parent:offspring | −0.08 ± 0.36 | −0.23 ± 0.36 | 0.45 ± 0.15 | <.05 | 0.44 ± 0.17 | <.05 |
Father:son | −0.09 ± 0.84 | −0.38 ± 0.69 | 0.46 ± 0.19 | <.05 | 0.68 ± 0.15 | <.01 |
Father:daughter | −0.18 ± 0.41 | −0.30 ± 0.53 | 0.93 ± 0.09 | <.001 | 0.81 ± 0.25 | <.05 |
Mother:son | 0.00 ± 0.47 | −0.09 ± 0.64 | 0.78 ± 0.23 | <.05 | 0.74 ± 0.22 | <.05 |
Mother:daughter | −0.07 ± 0.89 | −0.07 ± 0.97 | 0.20 ± 0.40 | 0.19 ± 0.40 | ||
Sibling | 0.18 ± 0.39 | 0.21 ± 0.46 | −0.18 ± 0.77 | 0.30 ± 0.17 | ||
2nd degree | −0.11 | −0.15 | 0.12 | <.05 | 0.23 | <.001 |
Avuncular | −0.13 ± 0.19 | −0.16 ± 0.23 | 0.13 ± 0.03 | <.001 | 0.23 ± 0.03 | <.001 |
Grandparent | −0.04 ± 0.38 | −0.15 ± 0.33 | 0.21 ± 0.17 | 0.29 ± 0.16 | ||
3rd degree | −0.04 | −0.03 | −0.16 | −0.17 | ||
4th degree | −0.12 | −0.04 | 0.30 | 0.20 |
Variable . | ICT Positivity . | ICT Intensity . | Microfilaremia Positivity . | Microfilarial Density . | ||
---|---|---|---|---|---|---|
Value . | P Value . | Value . | P Value . | |||
1st degree | 0.03 | −0.09 | 0.43 | <.01 | 0.37 | <.05 |
Parent:offspring | −0.08 ± 0.36 | −0.23 ± 0.36 | 0.45 ± 0.15 | <.05 | 0.44 ± 0.17 | <.05 |
Father:son | −0.09 ± 0.84 | −0.38 ± 0.69 | 0.46 ± 0.19 | <.05 | 0.68 ± 0.15 | <.01 |
Father:daughter | −0.18 ± 0.41 | −0.30 ± 0.53 | 0.93 ± 0.09 | <.001 | 0.81 ± 0.25 | <.05 |
Mother:son | 0.00 ± 0.47 | −0.09 ± 0.64 | 0.78 ± 0.23 | <.05 | 0.74 ± 0.22 | <.05 |
Mother:daughter | −0.07 ± 0.89 | −0.07 ± 0.97 | 0.20 ± 0.40 | 0.19 ± 0.40 | ||
Sibling | 0.18 ± 0.39 | 0.21 ± 0.46 | −0.18 ± 0.77 | 0.30 ± 0.17 | ||
2nd degree | −0.11 | −0.15 | 0.12 | <.05 | 0.23 | <.001 |
Avuncular | −0.13 ± 0.19 | −0.16 ± 0.23 | 0.13 ± 0.03 | <.001 | 0.23 ± 0.03 | <.001 |
Grandparent | −0.04 ± 0.38 | −0.15 ± 0.33 | 0.21 ± 0.17 | 0.29 ± 0.16 | ||
3rd degree | −0.04 | −0.03 | −0.16 | −0.17 | ||
4th degree | −0.12 | −0.04 | 0.30 | 0.20 |
Data are correlation coefficient ± standard error. The asymptotic standard error of a given correlation was estimated by using a second-order Taylor series expansion and replacing all correlation parameters with their respective estimates. Correlations were assessed for all available pair types. Results from saturated models and adjustments were individual risk factors (bed net, hunting, night in the bush, age, sex, and latrine) and environmental variables (road, main river, stream, dry creek, holes, and slate), with a household random effect.
Abbreviation: ICT, immunochromatographic test.
Adjusted Intrafamilial Correlation Coefficients From the Familial Aggregation Analysis
Variable . | ICT Positivity . | ICT Intensity . | Microfilaremia Positivity . | Microfilarial Density . | ||
---|---|---|---|---|---|---|
Value . | P Value . | Value . | P Value . | |||
1st degree | 0.03 | −0.09 | 0.43 | <.01 | 0.37 | <.05 |
Parent:offspring | −0.08 ± 0.36 | −0.23 ± 0.36 | 0.45 ± 0.15 | <.05 | 0.44 ± 0.17 | <.05 |
Father:son | −0.09 ± 0.84 | −0.38 ± 0.69 | 0.46 ± 0.19 | <.05 | 0.68 ± 0.15 | <.01 |
Father:daughter | −0.18 ± 0.41 | −0.30 ± 0.53 | 0.93 ± 0.09 | <.001 | 0.81 ± 0.25 | <.05 |
Mother:son | 0.00 ± 0.47 | −0.09 ± 0.64 | 0.78 ± 0.23 | <.05 | 0.74 ± 0.22 | <.05 |
Mother:daughter | −0.07 ± 0.89 | −0.07 ± 0.97 | 0.20 ± 0.40 | 0.19 ± 0.40 | ||
Sibling | 0.18 ± 0.39 | 0.21 ± 0.46 | −0.18 ± 0.77 | 0.30 ± 0.17 | ||
2nd degree | −0.11 | −0.15 | 0.12 | <.05 | 0.23 | <.001 |
Avuncular | −0.13 ± 0.19 | −0.16 ± 0.23 | 0.13 ± 0.03 | <.001 | 0.23 ± 0.03 | <.001 |
Grandparent | −0.04 ± 0.38 | −0.15 ± 0.33 | 0.21 ± 0.17 | 0.29 ± 0.16 | ||
3rd degree | −0.04 | −0.03 | −0.16 | −0.17 | ||
4th degree | −0.12 | −0.04 | 0.30 | 0.20 |
Variable . | ICT Positivity . | ICT Intensity . | Microfilaremia Positivity . | Microfilarial Density . | ||
---|---|---|---|---|---|---|
Value . | P Value . | Value . | P Value . | |||
1st degree | 0.03 | −0.09 | 0.43 | <.01 | 0.37 | <.05 |
Parent:offspring | −0.08 ± 0.36 | −0.23 ± 0.36 | 0.45 ± 0.15 | <.05 | 0.44 ± 0.17 | <.05 |
Father:son | −0.09 ± 0.84 | −0.38 ± 0.69 | 0.46 ± 0.19 | <.05 | 0.68 ± 0.15 | <.01 |
Father:daughter | −0.18 ± 0.41 | −0.30 ± 0.53 | 0.93 ± 0.09 | <.001 | 0.81 ± 0.25 | <.05 |
Mother:son | 0.00 ± 0.47 | −0.09 ± 0.64 | 0.78 ± 0.23 | <.05 | 0.74 ± 0.22 | <.05 |
Mother:daughter | −0.07 ± 0.89 | −0.07 ± 0.97 | 0.20 ± 0.40 | 0.19 ± 0.40 | ||
Sibling | 0.18 ± 0.39 | 0.21 ± 0.46 | −0.18 ± 0.77 | 0.30 ± 0.17 | ||
2nd degree | −0.11 | −0.15 | 0.12 | <.05 | 0.23 | <.001 |
Avuncular | −0.13 ± 0.19 | −0.16 ± 0.23 | 0.13 ± 0.03 | <.001 | 0.23 ± 0.03 | <.001 |
Grandparent | −0.04 ± 0.38 | −0.15 ± 0.33 | 0.21 ± 0.17 | 0.29 ± 0.16 | ||
3rd degree | −0.04 | −0.03 | −0.16 | −0.17 | ||
4th degree | −0.12 | −0.04 | 0.30 | 0.20 |
Data are correlation coefficient ± standard error. The asymptotic standard error of a given correlation was estimated by using a second-order Taylor series expansion and replacing all correlation parameters with their respective estimates. Correlations were assessed for all available pair types. Results from saturated models and adjustments were individual risk factors (bed net, hunting, night in the bush, age, sex, and latrine) and environmental variables (road, main river, stream, dry creek, holes, and slate), with a household random effect.
Abbreviation: ICT, immunochromatographic test.
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