Table A1

Patient characteristics at ICD implantation

VariablesAll patients (n = 1020)Patients on digitalis (n = 438)Patients not on digitalis (n = 582)P-value
Age mean (SD) (years)63 (12)63 (11)62 (13)n.s.
Male gender, n (%)809 (79)345 (79)464 (80)n.s.
Primary prevention, n (%)585 (58)251 (57)334 (57)n.s.
Secondary prevention, n (%)430 (42)182 (43)248 (43)
Ischaemic heart disease, n (%)690 (68)288 (66)402 (69)0.02
Non-ischaemic heart disease, n (%)430 (32)150 (34)248 (43)
NYHA classification, n (%)<0.001
 0 + I256 (25)52 (12)204 (35)
 II348 (34)156 (36)192 (33)
 III257 (25)167 (38)90 (15)
 IV23 (2)16 (4)7 (1)
LVEF mean, % (SD)33 (13)26 (8)38 (14)<0.001
ICD type, n (%)<0.001
 Single chamber561 (55)233 (53)328 (56)
 Dual chamber295 (29)106 (24)189 (32)
 CRT-D159 (16)94 (21)65 (11)
QRS ≥120 ms, n (%)397 (39)206 (47)191 (33)<0.001
Documented AF, n (%)150 (15)94 (21)56 (10)<0.001
Diabetes mellitus, n (%)311 (30)169 (39)142 (24)<0.001
Chronic kidney failure, n (%)258 (25)150 (34)108 (19)<0.001
VariablesAll patients (n = 1020)Patients on digitalis (n = 438)Patients not on digitalis (n = 582)P-value
Age mean (SD) (years)63 (12)63 (11)62 (13)n.s.
Male gender, n (%)809 (79)345 (79)464 (80)n.s.
Primary prevention, n (%)585 (58)251 (57)334 (57)n.s.
Secondary prevention, n (%)430 (42)182 (43)248 (43)
Ischaemic heart disease, n (%)690 (68)288 (66)402 (69)0.02
Non-ischaemic heart disease, n (%)430 (32)150 (34)248 (43)
NYHA classification, n (%)<0.001
 0 + I256 (25)52 (12)204 (35)
 II348 (34)156 (36)192 (33)
 III257 (25)167 (38)90 (15)
 IV23 (2)16 (4)7 (1)
LVEF mean, % (SD)33 (13)26 (8)38 (14)<0.001
ICD type, n (%)<0.001
 Single chamber561 (55)233 (53)328 (56)
 Dual chamber295 (29)106 (24)189 (32)
 CRT-D159 (16)94 (21)65 (11)
QRS ≥120 ms, n (%)397 (39)206 (47)191 (33)<0.001
Documented AF, n (%)150 (15)94 (21)56 (10)<0.001
Diabetes mellitus, n (%)311 (30)169 (39)142 (24)<0.001
Chronic kidney failure, n (%)258 (25)150 (34)108 (19)<0.001

SD, standard deviation; NYHA, New York Heart Association classification; LVEF, left ventricular ejection fraction; CRT-D, cardiac resynchronization therapy-defibrillator; AF, atrial fibrillation.

Table A1

Patient characteristics at ICD implantation

VariablesAll patients (n = 1020)Patients on digitalis (n = 438)Patients not on digitalis (n = 582)P-value
Age mean (SD) (years)63 (12)63 (11)62 (13)n.s.
Male gender, n (%)809 (79)345 (79)464 (80)n.s.
Primary prevention, n (%)585 (58)251 (57)334 (57)n.s.
Secondary prevention, n (%)430 (42)182 (43)248 (43)
Ischaemic heart disease, n (%)690 (68)288 (66)402 (69)0.02
Non-ischaemic heart disease, n (%)430 (32)150 (34)248 (43)
NYHA classification, n (%)<0.001
 0 + I256 (25)52 (12)204 (35)
 II348 (34)156 (36)192 (33)
 III257 (25)167 (38)90 (15)
 IV23 (2)16 (4)7 (1)
LVEF mean, % (SD)33 (13)26 (8)38 (14)<0.001
ICD type, n (%)<0.001
 Single chamber561 (55)233 (53)328 (56)
 Dual chamber295 (29)106 (24)189 (32)
 CRT-D159 (16)94 (21)65 (11)
QRS ≥120 ms, n (%)397 (39)206 (47)191 (33)<0.001
Documented AF, n (%)150 (15)94 (21)56 (10)<0.001
Diabetes mellitus, n (%)311 (30)169 (39)142 (24)<0.001
Chronic kidney failure, n (%)258 (25)150 (34)108 (19)<0.001
VariablesAll patients (n = 1020)Patients on digitalis (n = 438)Patients not on digitalis (n = 582)P-value
Age mean (SD) (years)63 (12)63 (11)62 (13)n.s.
Male gender, n (%)809 (79)345 (79)464 (80)n.s.
Primary prevention, n (%)585 (58)251 (57)334 (57)n.s.
Secondary prevention, n (%)430 (42)182 (43)248 (43)
Ischaemic heart disease, n (%)690 (68)288 (66)402 (69)0.02
Non-ischaemic heart disease, n (%)430 (32)150 (34)248 (43)
NYHA classification, n (%)<0.001
 0 + I256 (25)52 (12)204 (35)
 II348 (34)156 (36)192 (33)
 III257 (25)167 (38)90 (15)
 IV23 (2)16 (4)7 (1)
LVEF mean, % (SD)33 (13)26 (8)38 (14)<0.001
ICD type, n (%)<0.001
 Single chamber561 (55)233 (53)328 (56)
 Dual chamber295 (29)106 (24)189 (32)
 CRT-D159 (16)94 (21)65 (11)
QRS ≥120 ms, n (%)397 (39)206 (47)191 (33)<0.001
Documented AF, n (%)150 (15)94 (21)56 (10)<0.001
Diabetes mellitus, n (%)311 (30)169 (39)142 (24)<0.001
Chronic kidney failure, n (%)258 (25)150 (34)108 (19)<0.001

SD, standard deviation; NYHA, New York Heart Association classification; LVEF, left ventricular ejection fraction; CRT-D, cardiac resynchronization therapy-defibrillator; AF, atrial fibrillation.

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