Table 2

Predictors of CFC improvement

CFC increaseOR (95% CI)P-value
Baseline CFC groups<0.01
 Severely reduced CFC vs. moderately reduced CFC4.84 (2.12–11.09)
 Severely reduced CFC vs. minimally reduced CFC5.77 (2.20–15.16)
  Moderately reduced CFC vs. minimally reduced CFC1.19 (0.67–2.13)
Demographics
 Gender (male vs. female)0.43 (0.17–1.10)0.08
 Age (years)0.99 (0.96–1.02)0.37
 BMI1.00 (0.94–1.07)0.99
Cardiovascular risk factors
 Hypertension1.37 (0.75–2.48)0.30
 Hypercholesterolaemia1.18 (0.61–1.84)0.83
 Diabetes mellitus0.69 (0.38–1.25)0.22
 Family history of CAD0.96 (0.52–1.64)0.87
 Smoking1.55 (0.79–3.08)0.21
Cardiac history
 History of MI0.56 (0.31–1.00)0.05
 History of PCI0.98 (0.51–1.89)0.95
 History of CABG0.48 (0.21–1.08)0.07
Medication
 Aspirin1.07 (0.34–3.33)0.91
 β-Blocker1.11 (0.54–2.26)0.78
 ACE inhibitor/ARB0.72 (0.40–1.3)0.28
 Statin0.76 (0.31–1.85)0.54
 Calcium channel blocker0.95 (0.52–1.75)0.87
Revascularization
 Surgical revascularization0.86 (0.33–2.29)0.77
CFC increaseOR (95% CI)P-value
Baseline CFC groups<0.01
 Severely reduced CFC vs. moderately reduced CFC4.84 (2.12–11.09)
 Severely reduced CFC vs. minimally reduced CFC5.77 (2.20–15.16)
  Moderately reduced CFC vs. minimally reduced CFC1.19 (0.67–2.13)
Demographics
 Gender (male vs. female)0.43 (0.17–1.10)0.08
 Age (years)0.99 (0.96–1.02)0.37
 BMI1.00 (0.94–1.07)0.99
Cardiovascular risk factors
 Hypertension1.37 (0.75–2.48)0.30
 Hypercholesterolaemia1.18 (0.61–1.84)0.83
 Diabetes mellitus0.69 (0.38–1.25)0.22
 Family history of CAD0.96 (0.52–1.64)0.87
 Smoking1.55 (0.79–3.08)0.21
Cardiac history
 History of MI0.56 (0.31–1.00)0.05
 History of PCI0.98 (0.51–1.89)0.95
 History of CABG0.48 (0.21–1.08)0.07
Medication
 Aspirin1.07 (0.34–3.33)0.91
 β-Blocker1.11 (0.54–2.26)0.78
 ACE inhibitor/ARB0.72 (0.40–1.3)0.28
 Statin0.76 (0.31–1.85)0.54
 Calcium channel blocker0.95 (0.52–1.75)0.87
Revascularization
 Surgical revascularization0.86 (0.33–2.29)0.77

ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; BMI, body mass index; CABG, coronary artery bypass graft; CAD, coronary artery disease; CFC, coronary flow capacity; LAD, left anterior descending coronary artery; MI, myocardial infarction; OR, odds ratio; PCI, percutaneous coronary intervention.

Table 2

Predictors of CFC improvement

CFC increaseOR (95% CI)P-value
Baseline CFC groups<0.01
 Severely reduced CFC vs. moderately reduced CFC4.84 (2.12–11.09)
 Severely reduced CFC vs. minimally reduced CFC5.77 (2.20–15.16)
  Moderately reduced CFC vs. minimally reduced CFC1.19 (0.67–2.13)
Demographics
 Gender (male vs. female)0.43 (0.17–1.10)0.08
 Age (years)0.99 (0.96–1.02)0.37
 BMI1.00 (0.94–1.07)0.99
Cardiovascular risk factors
 Hypertension1.37 (0.75–2.48)0.30
 Hypercholesterolaemia1.18 (0.61–1.84)0.83
 Diabetes mellitus0.69 (0.38–1.25)0.22
 Family history of CAD0.96 (0.52–1.64)0.87
 Smoking1.55 (0.79–3.08)0.21
Cardiac history
 History of MI0.56 (0.31–1.00)0.05
 History of PCI0.98 (0.51–1.89)0.95
 History of CABG0.48 (0.21–1.08)0.07
Medication
 Aspirin1.07 (0.34–3.33)0.91
 β-Blocker1.11 (0.54–2.26)0.78
 ACE inhibitor/ARB0.72 (0.40–1.3)0.28
 Statin0.76 (0.31–1.85)0.54
 Calcium channel blocker0.95 (0.52–1.75)0.87
Revascularization
 Surgical revascularization0.86 (0.33–2.29)0.77
CFC increaseOR (95% CI)P-value
Baseline CFC groups<0.01
 Severely reduced CFC vs. moderately reduced CFC4.84 (2.12–11.09)
 Severely reduced CFC vs. minimally reduced CFC5.77 (2.20–15.16)
  Moderately reduced CFC vs. minimally reduced CFC1.19 (0.67–2.13)
Demographics
 Gender (male vs. female)0.43 (0.17–1.10)0.08
 Age (years)0.99 (0.96–1.02)0.37
 BMI1.00 (0.94–1.07)0.99
Cardiovascular risk factors
 Hypertension1.37 (0.75–2.48)0.30
 Hypercholesterolaemia1.18 (0.61–1.84)0.83
 Diabetes mellitus0.69 (0.38–1.25)0.22
 Family history of CAD0.96 (0.52–1.64)0.87
 Smoking1.55 (0.79–3.08)0.21
Cardiac history
 History of MI0.56 (0.31–1.00)0.05
 History of PCI0.98 (0.51–1.89)0.95
 History of CABG0.48 (0.21–1.08)0.07
Medication
 Aspirin1.07 (0.34–3.33)0.91
 β-Blocker1.11 (0.54–2.26)0.78
 ACE inhibitor/ARB0.72 (0.40–1.3)0.28
 Statin0.76 (0.31–1.85)0.54
 Calcium channel blocker0.95 (0.52–1.75)0.87
Revascularization
 Surgical revascularization0.86 (0.33–2.29)0.77

ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; BMI, body mass index; CABG, coronary artery bypass graft; CAD, coronary artery disease; CFC, coronary flow capacity; LAD, left anterior descending coronary artery; MI, myocardial infarction; OR, odds ratio; PCI, percutaneous coronary intervention.

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