Associations of frequency and type of shift work with cardiovascular disease (CVD)
| . | Incident CVD . | Fatal CVD . | ||
|---|---|---|---|---|
| . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Frequency of shift | ||||
| Model 0 | ||||
| Sometimes | 1.23 (1.17, 1.30) | <0.0001 | 1.37 (1.16, 1.62) | 0.0003 |
| Always | 1.27 (1.20, 1.35) | <0.0001 | 1.52 (1.26, 1.83) | <0.0001 |
| Model 1 | ||||
| Sometimes | 1.14 (1.09, 1.20) | <0.0001 | 1.24 (1.05, 1.47) | 0.01 |
| Always | 1.13 (1.07, 1.20) | <0.0001 | 1.32 (1.09, 1.59) | 0.004 |
| Model 2 | ||||
| Sometimes | 1.11 (1.05, 1.17) | 0.0002 | 1.21 (1.01, 1.45) | 0.04 |
| Always | 1.10 (1.03, 1.17) | 0.003 | 1.30 (1.07, 1.58) | 0.009 |
| Type of shift | ||||
| Model 0 | ||||
| Evening/weekend shifts | 1.25 (1.19, 1.32) | <0.0001 | 1.44 (1.20, 1.71) | <0.0001 |
| Night shifts | 1.25 (1.18, 1.32) | <0.0001 | 1.43 (1.20, 1.70) | <0.0001 |
| Model 1 | ||||
| Evening/weekend shifts | 1.16 (1.09, 1.22) | <0.0001 | 1.30 (1.08, 1.55) | 0.005 |
| Night shifts | 1.12 (1.06, 1.19) | <0.0001 | 1.25 (1.05, 1.50) | 0.01 |
| Model 2 | ||||
| Evening/weekend shifts | 1.13 (1.06, 1.20) | <0.0001 | 1.29 (1.07, 1.56) | 0.01 |
| Night shifts | 1.08 (1.02, 1.15) | 0.007 | 1.21 (1.00, 1.46) | 0.05 |
| . | Incident CVD . | Fatal CVD . | ||
|---|---|---|---|---|
| . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Frequency of shift | ||||
| Model 0 | ||||
| Sometimes | 1.23 (1.17, 1.30) | <0.0001 | 1.37 (1.16, 1.62) | 0.0003 |
| Always | 1.27 (1.20, 1.35) | <0.0001 | 1.52 (1.26, 1.83) | <0.0001 |
| Model 1 | ||||
| Sometimes | 1.14 (1.09, 1.20) | <0.0001 | 1.24 (1.05, 1.47) | 0.01 |
| Always | 1.13 (1.07, 1.20) | <0.0001 | 1.32 (1.09, 1.59) | 0.004 |
| Model 2 | ||||
| Sometimes | 1.11 (1.05, 1.17) | 0.0002 | 1.21 (1.01, 1.45) | 0.04 |
| Always | 1.10 (1.03, 1.17) | 0.003 | 1.30 (1.07, 1.58) | 0.009 |
| Type of shift | ||||
| Model 0 | ||||
| Evening/weekend shifts | 1.25 (1.19, 1.32) | <0.0001 | 1.44 (1.20, 1.71) | <0.0001 |
| Night shifts | 1.25 (1.18, 1.32) | <0.0001 | 1.43 (1.20, 1.70) | <0.0001 |
| Model 1 | ||||
| Evening/weekend shifts | 1.16 (1.09, 1.22) | <0.0001 | 1.30 (1.08, 1.55) | 0.005 |
| Night shifts | 1.12 (1.06, 1.19) | <0.0001 | 1.25 (1.05, 1.50) | 0.01 |
| Model 2 | ||||
| Evening/weekend shifts | 1.13 (1.06, 1.20) | <0.0001 | 1.29 (1.07, 1.56) | 0.01 |
| Night shifts | 1.08 (1.02, 1.15) | 0.007 | 1.21 (1.00, 1.46) | 0.05 |
Model 0: age and sex only; Model 1: education and deprivation additionally; Model 2: hours of work per week, duration of current job, walking/standing at work, heavy manual/physical work additionally.
Associations of frequency and type of shift work with cardiovascular disease (CVD)
| . | Incident CVD . | Fatal CVD . | ||
|---|---|---|---|---|
| . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Frequency of shift | ||||
| Model 0 | ||||
| Sometimes | 1.23 (1.17, 1.30) | <0.0001 | 1.37 (1.16, 1.62) | 0.0003 |
| Always | 1.27 (1.20, 1.35) | <0.0001 | 1.52 (1.26, 1.83) | <0.0001 |
| Model 1 | ||||
| Sometimes | 1.14 (1.09, 1.20) | <0.0001 | 1.24 (1.05, 1.47) | 0.01 |
| Always | 1.13 (1.07, 1.20) | <0.0001 | 1.32 (1.09, 1.59) | 0.004 |
| Model 2 | ||||
| Sometimes | 1.11 (1.05, 1.17) | 0.0002 | 1.21 (1.01, 1.45) | 0.04 |
| Always | 1.10 (1.03, 1.17) | 0.003 | 1.30 (1.07, 1.58) | 0.009 |
| Type of shift | ||||
| Model 0 | ||||
| Evening/weekend shifts | 1.25 (1.19, 1.32) | <0.0001 | 1.44 (1.20, 1.71) | <0.0001 |
| Night shifts | 1.25 (1.18, 1.32) | <0.0001 | 1.43 (1.20, 1.70) | <0.0001 |
| Model 1 | ||||
| Evening/weekend shifts | 1.16 (1.09, 1.22) | <0.0001 | 1.30 (1.08, 1.55) | 0.005 |
| Night shifts | 1.12 (1.06, 1.19) | <0.0001 | 1.25 (1.05, 1.50) | 0.01 |
| Model 2 | ||||
| Evening/weekend shifts | 1.13 (1.06, 1.20) | <0.0001 | 1.29 (1.07, 1.56) | 0.01 |
| Night shifts | 1.08 (1.02, 1.15) | 0.007 | 1.21 (1.00, 1.46) | 0.05 |
| . | Incident CVD . | Fatal CVD . | ||
|---|---|---|---|---|
| . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Frequency of shift | ||||
| Model 0 | ||||
| Sometimes | 1.23 (1.17, 1.30) | <0.0001 | 1.37 (1.16, 1.62) | 0.0003 |
| Always | 1.27 (1.20, 1.35) | <0.0001 | 1.52 (1.26, 1.83) | <0.0001 |
| Model 1 | ||||
| Sometimes | 1.14 (1.09, 1.20) | <0.0001 | 1.24 (1.05, 1.47) | 0.01 |
| Always | 1.13 (1.07, 1.20) | <0.0001 | 1.32 (1.09, 1.59) | 0.004 |
| Model 2 | ||||
| Sometimes | 1.11 (1.05, 1.17) | 0.0002 | 1.21 (1.01, 1.45) | 0.04 |
| Always | 1.10 (1.03, 1.17) | 0.003 | 1.30 (1.07, 1.58) | 0.009 |
| Type of shift | ||||
| Model 0 | ||||
| Evening/weekend shifts | 1.25 (1.19, 1.32) | <0.0001 | 1.44 (1.20, 1.71) | <0.0001 |
| Night shifts | 1.25 (1.18, 1.32) | <0.0001 | 1.43 (1.20, 1.70) | <0.0001 |
| Model 1 | ||||
| Evening/weekend shifts | 1.16 (1.09, 1.22) | <0.0001 | 1.30 (1.08, 1.55) | 0.005 |
| Night shifts | 1.12 (1.06, 1.19) | <0.0001 | 1.25 (1.05, 1.50) | 0.01 |
| Model 2 | ||||
| Evening/weekend shifts | 1.13 (1.06, 1.20) | <0.0001 | 1.29 (1.07, 1.56) | 0.01 |
| Night shifts | 1.08 (1.02, 1.15) | 0.007 | 1.21 (1.00, 1.46) | 0.05 |
Model 0: age and sex only; Model 1: education and deprivation additionally; Model 2: hours of work per week, duration of current job, walking/standing at work, heavy manual/physical work additionally.
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