Table 2. Open in new tab The association...

	Tertiles categories of miR-122			β (SE) per log-transformed miR-122 increment	P for trend
n	74	73	73
miR-122^a	9.0 [8.7, 9.3]	9.9 [9.7, 10.0]	10.8 [10.4, 11.0]
Hepatic fat content^a	3.4 [1.0, 9.8]	5.2 [2.1, 13.1]	15.0 [3.7, 24.6]
Model 1^b	Reference	0.56 (1.48)	7.92 (1.48)	4.11 (0.73)	<0.001
Model 2^c	Reference	0.09 (1.48)	7.25 (1.47)	3.79 (0.73)	<0.001

	Tertiles categories of miR-122			β (SE) per log-transformed miR-122 increment	P for trend
n	74	73	73
miR-122^a	9.0 [8.7, 9.3]	9.9 [9.7, 10.0]	10.8 [10.4, 11.0]
Hepatic fat content^a	3.4 [1.0, 9.8]	5.2 [2.1, 13.1]	15.0 [3.7, 24.6]
Model 1^b	Reference	0.56 (1.48)	7.92 (1.48)	4.11 (0.73)	<0.001
Model 2^c	Reference	0.09 (1.48)	7.25 (1.47)	3.79 (0.73)	<0.001

Table 2.

The association between liver fat content and log-transformed miR-122 levels at baseline

	Tertiles categories of miR-122			β (SE) per log-transformed miR-122 increment	P for trend
	T1	T2	T3
n	74	73	73
miR-122^a	9.0 [8.7, 9.3]	9.9 [9.7, 10.0]	10.8 [10.4, 11.0]
Hepatic fat content^a	3.4 [1.0, 9.8]	5.2 [2.1, 13.1]	15.0 [3.7, 24.6]
Model 1^b	Reference	0.56 (1.48)	7.92 (1.48)	4.11 (0.73)	<0.001
Model 2^c	Reference	0.09 (1.48)	7.25 (1.47)	3.79 (0.73)	<0.001

	Tertiles categories of miR-122			β (SE) per log-transformed miR-122 increment	P for trend
	T1	T2	T3
n	74	73	73
miR-122^a	9.0 [8.7, 9.3]	9.9 [9.7, 10.0]	10.8 [10.4, 11.0]
Hepatic fat content^a	3.4 [1.0, 9.8]	5.2 [2.1, 13.1]	15.0 [3.7, 24.6]
Model 1^b	Reference	0.56 (1.48)	7.92 (1.48)	4.11 (0.73)	<0.001
Model 2^c	Reference	0.09 (1.48)	7.25 (1.47)	3.79 (0.73)	<0.001

Abbreviation: miR-122, microRNA-122.

^aData are given as median [25th, 75th].

^bAdjusted for age, sex, abdominal obesity status.

^cAdjusted for age, sex, abdominal obesity status, physical activity, serum high-density lipoprotein cholesterol, serum triglycerides, and fasting glucose levels.

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