| . | Europe (SIOP) . | North America (COG) . |
|---|---|---|
| Pure germinoma | M0 Chx, WVI24Gy, F-RT/boost 16Gy; if CR no boost (currently under evaluation) M+ RT CSI alone 24Gy, IF-RT/boost 16Gy42,43 | M0 ACNS1123: Chx WVI 18Gy, IF-RT/boost 12Gy for CR; WVI 24Gy, IF-RT/boost 12Gy if no CR is currently under evaluation |
| NGGCT | M0 Chx, IF-RT 54Gy (surgery if not CR before RT) M+ Chx, CSI 30Gy, IF-RT/boost 24Gy29 | M0 ACNS0122:Chx, CSI 36Gy, boost 18Gy ACNS1123: Chx, WVI/30.6Gy, boost 23.4Gy M+ ACNS0122: CSI 36Gy, boost 18Gy28,39 |
| Teratoma | No detailed recommendations (register) | No detailed recommendations |
| . | Europe (SIOP) . | North America (COG) . |
|---|---|---|
| Pure germinoma | M0 Chx, WVI24Gy, F-RT/boost 16Gy; if CR no boost (currently under evaluation) M+ RT CSI alone 24Gy, IF-RT/boost 16Gy42,43 | M0 ACNS1123: Chx WVI 18Gy, IF-RT/boost 12Gy for CR; WVI 24Gy, IF-RT/boost 12Gy if no CR is currently under evaluation |
| NGGCT | M0 Chx, IF-RT 54Gy (surgery if not CR before RT) M+ Chx, CSI 30Gy, IF-RT/boost 24Gy29 | M0 ACNS0122:Chx, CSI 36Gy, boost 18Gy ACNS1123: Chx, WVI/30.6Gy, boost 23.4Gy M+ ACNS0122: CSI 36Gy, boost 18Gy28,39 |
| Teratoma | No detailed recommendations (register) | No detailed recommendations |
Abbreviations: Chx: chemotherapy; CSI: craniospinal irradiation; F-RT: focal irradiation; NGGCT: non-germinomatous germ cell tumors; WVI, whole ventricular irradiation.
| . | Europe (SIOP) . | North America (COG) . |
|---|---|---|
| Pure germinoma | M0 Chx, WVI24Gy, F-RT/boost 16Gy; if CR no boost (currently under evaluation) M+ RT CSI alone 24Gy, IF-RT/boost 16Gy42,43 | M0 ACNS1123: Chx WVI 18Gy, IF-RT/boost 12Gy for CR; WVI 24Gy, IF-RT/boost 12Gy if no CR is currently under evaluation |
| NGGCT | M0 Chx, IF-RT 54Gy (surgery if not CR before RT) M+ Chx, CSI 30Gy, IF-RT/boost 24Gy29 | M0 ACNS0122:Chx, CSI 36Gy, boost 18Gy ACNS1123: Chx, WVI/30.6Gy, boost 23.4Gy M+ ACNS0122: CSI 36Gy, boost 18Gy28,39 |
| Teratoma | No detailed recommendations (register) | No detailed recommendations |
| . | Europe (SIOP) . | North America (COG) . |
|---|---|---|
| Pure germinoma | M0 Chx, WVI24Gy, F-RT/boost 16Gy; if CR no boost (currently under evaluation) M+ RT CSI alone 24Gy, IF-RT/boost 16Gy42,43 | M0 ACNS1123: Chx WVI 18Gy, IF-RT/boost 12Gy for CR; WVI 24Gy, IF-RT/boost 12Gy if no CR is currently under evaluation |
| NGGCT | M0 Chx, IF-RT 54Gy (surgery if not CR before RT) M+ Chx, CSI 30Gy, IF-RT/boost 24Gy29 | M0 ACNS0122:Chx, CSI 36Gy, boost 18Gy ACNS1123: Chx, WVI/30.6Gy, boost 23.4Gy M+ ACNS0122: CSI 36Gy, boost 18Gy28,39 |
| Teratoma | No detailed recommendations (register) | No detailed recommendations |
Abbreviations: Chx: chemotherapy; CSI: craniospinal irradiation; F-RT: focal irradiation; NGGCT: non-germinomatous germ cell tumors; WVI, whole ventricular irradiation.
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