Table 3.

Changes in biochemical parameters during the study

ONS
ONS + RE
Baseline (n = 19)6 weeks (n = 19)Δc12 weeks (n = 19)ΔdBaseline (n = 17)6 weeks (n = 17)Δc12 weeks (n = 17)Δd
Hemoglobin (g/dL)8.1 (7–10)9.2 (8–10)a1.1 (−0.4–2.8)8.4 (7.4–10)0.2 (−0.7–1.2)7.4 (6.6–9.1)9 (7.6–10)b1.1 (0.3–1.7)9 (7.7–10)1.3 (−0.05–2.3)
Total lymphocytescount (cells/mm3)977.6 (767–1165)878.4 (764–1068)−81.4 (−317.1–220.3)996.3 (886.2–1161)35.3 (−140.5–228.6)702 (586.5–1022.85)877.2 (654.5–1014)50.1 (−169.8–203.2)720 (637.2–798.5)−25.5 (319.3–68.55)
Creatinine (mg/dL)15.7 ± 512.7 ± 5.4a−3 ± 5.813.7 ± 4.8−2 ± 5.313.9 ± 4.912.1 ± 6−1.8 ± 5.712.4 ± 4.2−1.5 ± 3.5
Albumin (g/dL)3.5 ± 0.293.7 ± 0.46a0.21 ± 0.343.7 ± 0.35a0.16 ± 0.253.3 ± 0.253.7 ± 0.38b0.29 ± 0.323.7 ± 0 .33b0.28 ± 0.22
Phosphorus (mg/dL)6.4 ± 2.85.7 ± 2.5−0.68 ± 2.45.7 ± 1.9−0.67 ± 2.66.2 ± 2.75.5 ± 2.3−0.65 ± 3.16.4 ± 20.20 ± 2.6
Potassium (mmol/dL)6 (5.4–6.3)5.1 (4.5–5.8)−0.6 (−1–0.5)5.9 (5.2–6.7)0.0 (−0.8–0.7)5.5 (4.9–6)5 (4.4–6)−0.1 (−0.65–0.30)5.1 (4.8–5.4)−0.2 (−1–0.15)
ONS
ONS + RE
Baseline (n = 19)6 weeks (n = 19)Δc12 weeks (n = 19)ΔdBaseline (n = 17)6 weeks (n = 17)Δc12 weeks (n = 17)Δd
Hemoglobin (g/dL)8.1 (7–10)9.2 (8–10)a1.1 (−0.4–2.8)8.4 (7.4–10)0.2 (−0.7–1.2)7.4 (6.6–9.1)9 (7.6–10)b1.1 (0.3–1.7)9 (7.7–10)1.3 (−0.05–2.3)
Total lymphocytescount (cells/mm3)977.6 (767–1165)878.4 (764–1068)−81.4 (−317.1–220.3)996.3 (886.2–1161)35.3 (−140.5–228.6)702 (586.5–1022.85)877.2 (654.5–1014)50.1 (−169.8–203.2)720 (637.2–798.5)−25.5 (319.3–68.55)
Creatinine (mg/dL)15.7 ± 512.7 ± 5.4a−3 ± 5.813.7 ± 4.8−2 ± 5.313.9 ± 4.912.1 ± 6−1.8 ± 5.712.4 ± 4.2−1.5 ± 3.5
Albumin (g/dL)3.5 ± 0.293.7 ± 0.46a0.21 ± 0.343.7 ± 0.35a0.16 ± 0.253.3 ± 0.253.7 ± 0.38b0.29 ± 0.323.7 ± 0 .33b0.28 ± 0.22
Phosphorus (mg/dL)6.4 ± 2.85.7 ± 2.5−0.68 ± 2.45.7 ± 1.9−0.67 ± 2.66.2 ± 2.75.5 ± 2.3−0.65 ± 3.16.4 ± 20.20 ± 2.6
Potassium (mmol/dL)6 (5.4–6.3)5.1 (4.5–5.8)−0.6 (−1–0.5)5.9 (5.2–6.7)0.0 (−0.8–0.7)5.5 (4.9–6)5 (4.4–6)−0.1 (−0.65–0.30)5.1 (4.8–5.4)−0.2 (−1–0.15)

Biochemical indicators are mean ± SD or median (first and third quartiles). No statistical difference was found in deltas between groups.

ONS, oral nutritional supplementation; ONS + RE; oral nutritional supplementation plus resistance exercise.

aP < 0.05, compared with the ONS group at baseline.

bP < 0.05, compared with the ONS + RE group at baseline.

cΔ = difference between baseline and 6 weeks.

dΔ = difference between baseline and 12 weeks.

Table 3.

Changes in biochemical parameters during the study

ONS
ONS + RE
Baseline (n = 19)6 weeks (n = 19)Δc12 weeks (n = 19)ΔdBaseline (n = 17)6 weeks (n = 17)Δc12 weeks (n = 17)Δd
Hemoglobin (g/dL)8.1 (7–10)9.2 (8–10)a1.1 (−0.4–2.8)8.4 (7.4–10)0.2 (−0.7–1.2)7.4 (6.6–9.1)9 (7.6–10)b1.1 (0.3–1.7)9 (7.7–10)1.3 (−0.05–2.3)
Total lymphocytescount (cells/mm3)977.6 (767–1165)878.4 (764–1068)−81.4 (−317.1–220.3)996.3 (886.2–1161)35.3 (−140.5–228.6)702 (586.5–1022.85)877.2 (654.5–1014)50.1 (−169.8–203.2)720 (637.2–798.5)−25.5 (319.3–68.55)
Creatinine (mg/dL)15.7 ± 512.7 ± 5.4a−3 ± 5.813.7 ± 4.8−2 ± 5.313.9 ± 4.912.1 ± 6−1.8 ± 5.712.4 ± 4.2−1.5 ± 3.5
Albumin (g/dL)3.5 ± 0.293.7 ± 0.46a0.21 ± 0.343.7 ± 0.35a0.16 ± 0.253.3 ± 0.253.7 ± 0.38b0.29 ± 0.323.7 ± 0 .33b0.28 ± 0.22
Phosphorus (mg/dL)6.4 ± 2.85.7 ± 2.5−0.68 ± 2.45.7 ± 1.9−0.67 ± 2.66.2 ± 2.75.5 ± 2.3−0.65 ± 3.16.4 ± 20.20 ± 2.6
Potassium (mmol/dL)6 (5.4–6.3)5.1 (4.5–5.8)−0.6 (−1–0.5)5.9 (5.2–6.7)0.0 (−0.8–0.7)5.5 (4.9–6)5 (4.4–6)−0.1 (−0.65–0.30)5.1 (4.8–5.4)−0.2 (−1–0.15)
ONS
ONS + RE
Baseline (n = 19)6 weeks (n = 19)Δc12 weeks (n = 19)ΔdBaseline (n = 17)6 weeks (n = 17)Δc12 weeks (n = 17)Δd
Hemoglobin (g/dL)8.1 (7–10)9.2 (8–10)a1.1 (−0.4–2.8)8.4 (7.4–10)0.2 (−0.7–1.2)7.4 (6.6–9.1)9 (7.6–10)b1.1 (0.3–1.7)9 (7.7–10)1.3 (−0.05–2.3)
Total lymphocytescount (cells/mm3)977.6 (767–1165)878.4 (764–1068)−81.4 (−317.1–220.3)996.3 (886.2–1161)35.3 (−140.5–228.6)702 (586.5–1022.85)877.2 (654.5–1014)50.1 (−169.8–203.2)720 (637.2–798.5)−25.5 (319.3–68.55)
Creatinine (mg/dL)15.7 ± 512.7 ± 5.4a−3 ± 5.813.7 ± 4.8−2 ± 5.313.9 ± 4.912.1 ± 6−1.8 ± 5.712.4 ± 4.2−1.5 ± 3.5
Albumin (g/dL)3.5 ± 0.293.7 ± 0.46a0.21 ± 0.343.7 ± 0.35a0.16 ± 0.253.3 ± 0.253.7 ± 0.38b0.29 ± 0.323.7 ± 0 .33b0.28 ± 0.22
Phosphorus (mg/dL)6.4 ± 2.85.7 ± 2.5−0.68 ± 2.45.7 ± 1.9−0.67 ± 2.66.2 ± 2.75.5 ± 2.3−0.65 ± 3.16.4 ± 20.20 ± 2.6
Potassium (mmol/dL)6 (5.4–6.3)5.1 (4.5–5.8)−0.6 (−1–0.5)5.9 (5.2–6.7)0.0 (−0.8–0.7)5.5 (4.9–6)5 (4.4–6)−0.1 (−0.65–0.30)5.1 (4.8–5.4)−0.2 (−1–0.15)

Biochemical indicators are mean ± SD or median (first and third quartiles). No statistical difference was found in deltas between groups.

ONS, oral nutritional supplementation; ONS + RE; oral nutritional supplementation plus resistance exercise.

aP < 0.05, compared with the ONS group at baseline.

bP < 0.05, compared with the ONS + RE group at baseline.

cΔ = difference between baseline and 6 weeks.

dΔ = difference between baseline and 12 weeks.

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