Table 2. Open in new tab Sensitivity and... | Oxford Academic

Table 2.

Open in new tab

Sensitivity and specificity of [TIMP2]•[IGFBP7] for moderate–severe AKI at both the 0.3 and 2.0 cutoffs, stratified by comorbidity subgroups

Comorbidity	Sensitivity or specificity	0.3 Cutoff			2.0 Cutoff
Comorbidity	Sensitivity or specificity	Without comorbidity (%)	With comorbidity (%)	P-value	Without comorbidity (%)	With comorbidity (%)	P-value
Coronary artery disease (n = 336)	Sensitivity	90	88	0.92	41	33	0.661
Coronary artery disease (n = 336)	Specificity	49	52	0.533	94	95	0.784
Congestive heart failure (n = 206)	Sensitivity	88	97	0.561	37	50	0.648
Congestive heart failure (n = 206)	Specificity	49	55	0.467	94	95	0.784
Chronic kidney disease (n = 97)	Sensitivity	88	100	0.698	40	31	0.678
Chronic kidney disease (n = 97)	Specificity	49	63	0.097	94	98	0.671
Chronic obstructive pulmonary disease (n = 236)	Sensitivity	88	96	0.698	41	30	0.661
Chronic obstructive pulmonary disease (n = 236)	Specificity	49	53	0.531	93	97	0.194
Diabetes mellitus (n = 326)	Sensitivity	86	94	0.561	40	38	0.86
Diabetes mellitus (n = 326)	Specificity	50	51	0.723	94	95	0.784
Hypertension (n = 700)	Sensitivity	89	89	1	50	36	0.648
Hypertension (n = 700)	Specificity	49	51	0.531	94	94	0.784

Comorbidity	Sensitivity or specificity	0.3 Cutoff			2.0 Cutoff
Comorbidity	Sensitivity or specificity	Without comorbidity (%)	With comorbidity (%)	P-value	Without comorbidity (%)	With comorbidity (%)	P-value
Coronary artery disease (n = 336)	Sensitivity	90	88	0.92	41	33	0.661
Coronary artery disease (n = 336)	Specificity	49	52	0.533	94	95	0.784
Congestive heart failure (n = 206)	Sensitivity	88	97	0.561	37	50	0.648
Congestive heart failure (n = 206)	Specificity	49	55	0.467	94	95	0.784
Chronic kidney disease (n = 97)	Sensitivity	88	100	0.698	40	31	0.678
Chronic kidney disease (n = 97)	Specificity	49	63	0.097	94	98	0.671
Chronic obstructive pulmonary disease (n = 236)	Sensitivity	88	96	0.698	41	30	0.661
Chronic obstructive pulmonary disease (n = 236)	Specificity	49	53	0.531	93	97	0.194
Diabetes mellitus (n = 326)	Sensitivity	86	94	0.561	40	38	0.86
Diabetes mellitus (n = 326)	Specificity	50	51	0.723	94	95	0.784
Hypertension (n = 700)	Sensitivity	89	89	1	50	36	0.648
Hypertension (n = 700)	Specificity	49	51	0.531	94	94	0.784

Table 2.

Open in new tab

Sensitivity and specificity of [TIMP2]•[IGFBP7] for moderate–severe AKI at both the 0.3 and 2.0 cutoffs, stratified by comorbidity subgroups

Comorbidity	Sensitivity or specificity	0.3 Cutoff			2.0 Cutoff
Comorbidity	Sensitivity or specificity	Without comorbidity (%)	With comorbidity (%)	P-value	Without comorbidity (%)	With comorbidity (%)	P-value
Coronary artery disease (n = 336)	Sensitivity	90	88	0.92	41	33	0.661
Coronary artery disease (n = 336)	Specificity	49	52	0.533	94	95	0.784
Congestive heart failure (n = 206)	Sensitivity	88	97	0.561	37	50	0.648
Congestive heart failure (n = 206)	Specificity	49	55	0.467	94	95	0.784
Chronic kidney disease (n = 97)	Sensitivity	88	100	0.698	40	31	0.678
Chronic kidney disease (n = 97)	Specificity	49	63	0.097	94	98	0.671
Chronic obstructive pulmonary disease (n = 236)	Sensitivity	88	96	0.698	41	30	0.661
Chronic obstructive pulmonary disease (n = 236)	Specificity	49	53	0.531	93	97	0.194
Diabetes mellitus (n = 326)	Sensitivity	86	94	0.561	40	38	0.86
Diabetes mellitus (n = 326)	Specificity	50	51	0.723	94	95	0.784
Hypertension (n = 700)	Sensitivity	89	89	1	50	36	0.648
Hypertension (n = 700)	Specificity	49	51	0.531	94	94	0.784

Comorbidity	Sensitivity or specificity	0.3 Cutoff			2.0 Cutoff
Comorbidity	Sensitivity or specificity	Without comorbidity (%)	With comorbidity (%)	P-value	Without comorbidity (%)	With comorbidity (%)	P-value
Coronary artery disease (n = 336)	Sensitivity	90	88	0.92	41	33	0.661
Coronary artery disease (n = 336)	Specificity	49	52	0.533	94	95	0.784
Congestive heart failure (n = 206)	Sensitivity	88	97	0.561	37	50	0.648
Congestive heart failure (n = 206)	Specificity	49	55	0.467	94	95	0.784
Chronic kidney disease (n = 97)	Sensitivity	88	100	0.698	40	31	0.678
Chronic kidney disease (n = 97)	Specificity	49	63	0.097	94	98	0.671
Chronic obstructive pulmonary disease (n = 236)	Sensitivity	88	96	0.698	41	30	0.661
Chronic obstructive pulmonary disease (n = 236)	Specificity	49	53	0.531	93	97	0.194
Diabetes mellitus (n = 326)	Sensitivity	86	94	0.561	40	38	0.86
Diabetes mellitus (n = 326)	Specificity	50	51	0.723	94	95	0.784
Hypertension (n = 700)	Sensitivity	89	89	1	50	36	0.648
Hypertension (n = 700)	Specificity	49	51	0.531	94	94	0.784