Table 1 Open in new tab Baseline...

	Total	NSTEMI	UAP	Other cardiac	NCCP	P-value
Descriptive factors
Patient count (%)	959 (100%)	125 (13.0%)	110 (11.5%)	151 (15.7%)	573 (59.7%)
Age, median years	64 (52–74)	70 (60–78)	70 (62–77)	71 (58–80)	59 (49–70)	<0.001
Male, %	60.5	68.8	74.5	58.9	56.4	<0.01
BMI, median, kg/m²	26 (24–30)	26 (24–29)	26 (25–30)	27 (24–30)	26 (24–30)	0.67
eGFR, median, mL/min/1.73 m²	85 (70–97)	80 (63–92)	78 (65–91)	74 (58–91)	88 (75–100)	<0.001
Symptom to arrival time, median hours	8.1 (3.4–47)	5.2 (2.8–25)	14.7 (5.5–86)	8.50 (3.5–47)	8.0 (3.4–47)	0.25
Early presenters ≤3 h, %	21.8	28.0	14.5	19.2	22.5	0.07
Late presenters >12 h, %	41.1	31.2	53.6	43.7	40.7	<0.01
Hospital stay, median hours	29 (21–69)	74 (63–114)	72 (44–118)	43 (24–79)	24 (19–35)	<0.001
Risk factors
Hypertension, %	41.7	49.6	53.6	42.4	37.5	<0.01
Hyperlipidaemia, known, %	20.2	19.2	33.6	20.5	17.8	<0.01
Hyperlipidaemia, new, %	0.8	0	1.8	0.7	0.9	0.49
Diabetes mellitus, %	12.4	17.6	25.5	9.9	9.4	<0.001
Insulin treatment, %	3.9	4.0	9.1	4.0	2.8	0.02
Family history, %	19.3	16.8	20.0	15.2	20.8	0.54
Unknown family history	12.6	12.0	16.4	11.3	12.4	0.63
Current smoker, %	20.6	18.4	18.2	21.2	21.5	0.79
Previous smoker, %	41.6	52.8	52.7	38.4	37.9	<0.01
Medical history
Prior MI, %	21.1	25.6	39.1	20.5	16.8	<0.001
Prior PCI, %	21.3	23.2	47.3	17.2	16.9	<0.001
Prior CABG, %	8.3	13.6	25.5	6.6	4.4	<0.001
Heart failure, %	4.8	6.4	5.5	9.3	3.1	0.01
Stroke, %	3.0	4.0	3.6	4.0	2.4	0.644
Peripheral vascular disease, %	2.3	4.0	6.4	1.3	1.4	0.006
Vital signs on admission
Systolic BP, median mmHg	143 (129–158)	147 (134–161)	148 (134–159)	134 (124–155)	142 (129–158)	0.009
Diastolic BP, median mmHg	82 (74–90)	84 (75–92)	80 (72–90)	80 (72–90)	82 (74–90)	0.157
Heart rate, median b.p.m.	72 (74–83)	75 (64–89)	70 (64–80)	82 (67–100)	70 (64–80)	<0.001
Electrocardiography
ST-segment depression, %	3.4	13.6	2.7	4.6	1.0	<0.001
T-wave inversion, %	3.0	8.0	5.5	2.6	1.6	0.001
Biomarker concentration
Troponin T, median ng/L	7 (3–18)	50 (24–176)	9 (5–18)	13 (5–24)	5 (3–9)	<0.001
Troponin I, median ng/L	4 (2–11)	120 (26–587)	5 (3–10)	8 (3–17)	3 (2–5)	<0.001
Copeptin, median pmol/L	4.5 (2.8–9.8)	7.9 (4.1–17.6)	4.7 (2.9–10.9)	7.5 (3.7–19.7)	3.8 (2.5–6.8)	<0.001
Glucose, median mmol/L	5.8 (5.3–6.7)	6.5 (5.8–7.9)	5.9 (5.4–6.7)	6.1 (5.5–7.3)	5.6 (5.2–6.4)	<0.001

Total

NSTEMI

UAP

Other cardiac

NCCP

P-value

Descriptive factors

Patient count (%)

959 (100%)

125 (13.0%)

110 (11.5%)

151 (15.7%)

573 (59.7%)

Age, median years

64 (52–74)

70 (60–78)

70 (62–77)

71 (58–80)

59 (49–70)

<0.001

Male, %

60.5

68.8

74.5

58.9

56.4

<0.01

BMI, median, kg/m²

26 (24–30)

26 (24–29)

26 (25–30)

27 (24–30)

26 (24–30)

0.67

eGFR, median, mL/min/1.73 m²

85 (70–97)

80 (63–92)

78 (65–91)

74 (58–91)

88 (75–100)

<0.001

Symptom to arrival time, median hours

8.1 (3.4–47)

5.2 (2.8–25)

14.7 (5.5–86)

8.50 (3.5–47)

8.0 (3.4–47)

0.25

Early presenters ≤3 h, %

21.8

28.0

14.5

19.2

22.5

0.07

Late presenters >12 h, %

41.1

31.2

53.6

43.7

40.7

<0.01

Hospital stay, median hours

29 (21–69)

74 (63–114)

72 (44–118)

43 (24–79)

24 (19–35)

<0.001

Risk factors

Hypertension, %

41.7

49.6

53.6

42.4

37.5

<0.01

Hyperlipidaemia, known, %

20.2

19.2

33.6

20.5

17.8

<0.01

Hyperlipidaemia, new, %

0.8

1.8

0.7

0.9

0.49

Diabetes mellitus, %

12.4

17.6

25.5

9.9

9.4

<0.001

Insulin treatment, %

3.9

4.0

9.1

4.0

2.8

0.02

Family history, %

19.3

16.8

20.0

15.2

20.8

0.54

Unknown family history

12.6

12.0

16.4

11.3

12.4

0.63

Current smoker, %

20.6

18.4

18.2

21.2

21.5

0.79

Previous smoker, %

41.6

52.8

52.7

38.4

37.9

<0.01

Medical history

Prior MI, %

21.1

25.6

39.1

20.5

16.8

<0.001

Prior PCI, %

21.3

23.2

47.3

17.2

16.9

<0.001

Prior CABG, %

8.3

13.6

25.5

6.6

4.4

<0.001

Heart failure, %

4.8

6.4

5.5

9.3

3.1

0.01

Stroke, %

3.0

4.0

3.6

4.0

2.4

0.644

Peripheral vascular disease, %

2.3

4.0

6.4

1.3

1.4

0.006

Vital signs on admission

Systolic BP, median mmHg

143 (129–158)

147 (134–161)

148 (134–159)

134 (124–155)

142 (129–158)

0.009

Diastolic BP, median mmHg

82 (74–90)

84 (75–92)

80 (72–90)

82 (74–90)

0.157

Heart rate, median b.p.m.

72 (74–83)

75 (64–89)

70 (64–80)

82 (67–100)

70 (64–80)

<0.001

Electrocardiography

ST-segment depression, %

3.4

13.6

2.7

4.6

1.0

<0.001

T-wave inversion, %

3.0

8.0

5.5

2.6

1.6

0.001

Biomarker concentration

Troponin T, median ng/L

7 (3–18)

50 (24–176)

9 (5–18)

13 (5–24)

5 (3–9)

<0.001

Troponin I, median ng/L

4 (2–11)

120 (26–587)

5 (3–10)

8 (3–17)

3 (2–5)

<0.001

Copeptin, median pmol/L

4.5 (2.8–9.8)

7.9 (4.1–17.6)

4.7 (2.9–10.9)

7.5 (3.7–19.7)

3.8 (2.5–6.8)

<0.001

Glucose, median mmol/L

5.8 (5.3–6.7)

6.5 (5.8–7.9)

5.9 (5.4–6.7)

6.1 (5.5–7.3)

5.6 (5.2–6.4)

<0.001

	Total	NSTEMI	UAP	Other cardiac	NCCP	P-value
Descriptive factors
Patient count (%)	959 (100%)	125 (13.0%)	110 (11.5%)	151 (15.7%)	573 (59.7%)
Age, median years	64 (52–74)	70 (60–78)	70 (62–77)	71 (58–80)	59 (49–70)	<0.001
Male, %	60.5	68.8	74.5	58.9	56.4	<0.01
BMI, median, kg/m²	26 (24–30)	26 (24–29)	26 (25–30)	27 (24–30)	26 (24–30)	0.67
eGFR, median, mL/min/1.73 m²	85 (70–97)	80 (63–92)	78 (65–91)	74 (58–91)	88 (75–100)	<0.001
Symptom to arrival time, median hours	8.1 (3.4–47)	5.2 (2.8–25)	14.7 (5.5–86)	8.50 (3.5–47)	8.0 (3.4–47)	0.25
Early presenters ≤3 h, %	21.8	28.0	14.5	19.2	22.5	0.07
Late presenters >12 h, %	41.1	31.2	53.6	43.7	40.7	<0.01
Hospital stay, median hours	29 (21–69)	74 (63–114)	72 (44–118)	43 (24–79)	24 (19–35)	<0.001
Risk factors
Hypertension, %	41.7	49.6	53.6	42.4	37.5	<0.01
Hyperlipidaemia, known, %	20.2	19.2	33.6	20.5	17.8	<0.01
Hyperlipidaemia, new, %	0.8	0	1.8	0.7	0.9	0.49
Diabetes mellitus, %	12.4	17.6	25.5	9.9	9.4	<0.001
Insulin treatment, %	3.9	4.0	9.1	4.0	2.8	0.02
Family history, %	19.3	16.8	20.0	15.2	20.8	0.54
Unknown family history	12.6	12.0	16.4	11.3	12.4	0.63
Current smoker, %	20.6	18.4	18.2	21.2	21.5	0.79
Previous smoker, %	41.6	52.8	52.7	38.4	37.9	<0.01
Medical history
Prior MI, %	21.1	25.6	39.1	20.5	16.8	<0.001
Prior PCI, %	21.3	23.2	47.3	17.2	16.9	<0.001
Prior CABG, %	8.3	13.6	25.5	6.6	4.4	<0.001
Heart failure, %	4.8	6.4	5.5	9.3	3.1	0.01
Stroke, %	3.0	4.0	3.6	4.0	2.4	0.644
Peripheral vascular disease, %	2.3	4.0	6.4	1.3	1.4	0.006
Vital signs on admission
Systolic BP, median mmHg	143 (129–158)	147 (134–161)	148 (134–159)	134 (124–155)	142 (129–158)	0.009
Diastolic BP, median mmHg	82 (74–90)	84 (75–92)	80 (72–90)	80 (72–90)	82 (74–90)	0.157
Heart rate, median b.p.m.	72 (74–83)	75 (64–89)	70 (64–80)	82 (67–100)	70 (64–80)	<0.001
Electrocardiography
ST-segment depression, %	3.4	13.6	2.7	4.6	1.0	<0.001
T-wave inversion, %	3.0	8.0	5.5	2.6	1.6	0.001
Biomarker concentration
Troponin T, median ng/L	7 (3–18)	50 (24–176)	9 (5–18)	13 (5–24)	5 (3–9)	<0.001
Troponin I, median ng/L	4 (2–11)	120 (26–587)	5 (3–10)	8 (3–17)	3 (2–5)	<0.001
Copeptin, median pmol/L	4.5 (2.8–9.8)	7.9 (4.1–17.6)	4.7 (2.9–10.9)	7.5 (3.7–19.7)	3.8 (2.5–6.8)	<0.001
Glucose, median mmol/L	5.8 (5.3–6.7)	6.5 (5.8–7.9)	5.9 (5.4–6.7)	6.1 (5.5–7.3)	5.6 (5.2–6.4)	<0.001

Table 1

Open in new tab

Baseline characteristics

	Total	NSTEMI	UAP	Other cardiac	NCCP	P-value
Descriptive factors
Patient count (%)	959 (100%)	125 (13.0%)	110 (11.5%)	151 (15.7%)	573 (59.7%)
Age, median years	64 (52–74)	70 (60–78)	70 (62–77)	71 (58–80)	59 (49–70)	<0.001
Male, %	60.5	68.8	74.5	58.9	56.4	<0.01
BMI, median, kg/m²	26 (24–30)	26 (24–29)	26 (25–30)	27 (24–30)	26 (24–30)	0.67
eGFR, median, mL/min/1.73 m²	85 (70–97)	80 (63–92)	78 (65–91)	74 (58–91)	88 (75–100)	<0.001
Symptom to arrival time, median hours	8.1 (3.4–47)	5.2 (2.8–25)	14.7 (5.5–86)	8.50 (3.5–47)	8.0 (3.4–47)	0.25
Early presenters ≤3 h, %	21.8	28.0	14.5	19.2	22.5	0.07
Late presenters >12 h, %	41.1	31.2	53.6	43.7	40.7	<0.01
Hospital stay, median hours	29 (21–69)	74 (63–114)	72 (44–118)	43 (24–79)	24 (19–35)	<0.001
Risk factors
Hypertension, %	41.7	49.6	53.6	42.4	37.5	<0.01
Hyperlipidaemia, known, %	20.2	19.2	33.6	20.5	17.8	<0.01
Hyperlipidaemia, new, %	0.8	0	1.8	0.7	0.9	0.49
Diabetes mellitus, %	12.4	17.6	25.5	9.9	9.4	<0.001
Insulin treatment, %	3.9	4.0	9.1	4.0	2.8	0.02
Family history, %	19.3	16.8	20.0	15.2	20.8	0.54
Unknown family history	12.6	12.0	16.4	11.3	12.4	0.63
Current smoker, %	20.6	18.4	18.2	21.2	21.5	0.79
Previous smoker, %	41.6	52.8	52.7	38.4	37.9	<0.01
Medical history
Prior MI, %	21.1	25.6	39.1	20.5	16.8	<0.001
Prior PCI, %	21.3	23.2	47.3	17.2	16.9	<0.001
Prior CABG, %	8.3	13.6	25.5	6.6	4.4	<0.001
Heart failure, %	4.8	6.4	5.5	9.3	3.1	0.01
Stroke, %	3.0	4.0	3.6	4.0	2.4	0.644
Peripheral vascular disease, %	2.3	4.0	6.4	1.3	1.4	0.006
Vital signs on admission
Systolic BP, median mmHg	143 (129–158)	147 (134–161)	148 (134–159)	134 (124–155)	142 (129–158)	0.009
Diastolic BP, median mmHg	82 (74–90)	84 (75–92)	80 (72–90)	80 (72–90)	82 (74–90)	0.157
Heart rate, median b.p.m.	72 (74–83)	75 (64–89)	70 (64–80)	82 (67–100)	70 (64–80)	<0.001
Electrocardiography
ST-segment depression, %	3.4	13.6	2.7	4.6	1.0	<0.001
T-wave inversion, %	3.0	8.0	5.5	2.6	1.6	0.001
Biomarker concentration
Troponin T, median ng/L	7 (3–18)	50 (24–176)	9 (5–18)	13 (5–24)	5 (3–9)	<0.001
Troponin I, median ng/L	4 (2–11)	120 (26–587)	5 (3–10)	8 (3–17)	3 (2–5)	<0.001
Copeptin, median pmol/L	4.5 (2.8–9.8)	7.9 (4.1–17.6)	4.7 (2.9–10.9)	7.5 (3.7–19.7)	3.8 (2.5–6.8)	<0.001
Glucose, median mmol/L	5.8 (5.3–6.7)	6.5 (5.8–7.9)	5.9 (5.4–6.7)	6.1 (5.5–7.3)	5.6 (5.2–6.4)	<0.001

	Total	NSTEMI	UAP	Other cardiac	NCCP	P-value
Descriptive factors
Patient count (%)	959 (100%)	125 (13.0%)	110 (11.5%)	151 (15.7%)	573 (59.7%)
Age, median years	64 (52–74)	70 (60–78)	70 (62–77)	71 (58–80)	59 (49–70)	<0.001
Male, %	60.5	68.8	74.5	58.9	56.4	<0.01
BMI, median, kg/m²	26 (24–30)	26 (24–29)	26 (25–30)	27 (24–30)	26 (24–30)	0.67
eGFR, median, mL/min/1.73 m²	85 (70–97)	80 (63–92)	78 (65–91)	74 (58–91)	88 (75–100)	<0.001
Symptom to arrival time, median hours	8.1 (3.4–47)	5.2 (2.8–25)	14.7 (5.5–86)	8.50 (3.5–47)	8.0 (3.4–47)	0.25
Early presenters ≤3 h, %	21.8	28.0	14.5	19.2	22.5	0.07
Late presenters >12 h, %	41.1	31.2	53.6	43.7	40.7	<0.01
Hospital stay, median hours	29 (21–69)	74 (63–114)	72 (44–118)	43 (24–79)	24 (19–35)	<0.001
Risk factors
Hypertension, %	41.7	49.6	53.6	42.4	37.5	<0.01
Hyperlipidaemia, known, %	20.2	19.2	33.6	20.5	17.8	<0.01
Hyperlipidaemia, new, %	0.8	0	1.8	0.7	0.9	0.49
Diabetes mellitus, %	12.4	17.6	25.5	9.9	9.4	<0.001
Insulin treatment, %	3.9	4.0	9.1	4.0	2.8	0.02
Family history, %	19.3	16.8	20.0	15.2	20.8	0.54
Unknown family history	12.6	12.0	16.4	11.3	12.4	0.63
Current smoker, %	20.6	18.4	18.2	21.2	21.5	0.79
Previous smoker, %	41.6	52.8	52.7	38.4	37.9	<0.01
Medical history
Prior MI, %	21.1	25.6	39.1	20.5	16.8	<0.001
Prior PCI, %	21.3	23.2	47.3	17.2	16.9	<0.001
Prior CABG, %	8.3	13.6	25.5	6.6	4.4	<0.001
Heart failure, %	4.8	6.4	5.5	9.3	3.1	0.01
Stroke, %	3.0	4.0	3.6	4.0	2.4	0.644
Peripheral vascular disease, %	2.3	4.0	6.4	1.3	1.4	0.006
Vital signs on admission
Systolic BP, median mmHg	143 (129–158)	147 (134–161)	148 (134–159)	134 (124–155)	142 (129–158)	0.009
Diastolic BP, median mmHg	82 (74–90)	84 (75–92)	80 (72–90)	80 (72–90)	82 (74–90)	0.157
Heart rate, median b.p.m.	72 (74–83)	75 (64–89)	70 (64–80)	82 (67–100)	70 (64–80)	<0.001
Electrocardiography
ST-segment depression, %	3.4	13.6	2.7	4.6	1.0	<0.001
T-wave inversion, %	3.0	8.0	5.5	2.6	1.6	0.001
Biomarker concentration
Troponin T, median ng/L	7 (3–18)	50 (24–176)	9 (5–18)	13 (5–24)	5 (3–9)	<0.001
Troponin I, median ng/L	4 (2–11)	120 (26–587)	5 (3–10)	8 (3–17)	3 (2–5)	<0.001
Copeptin, median pmol/L	4.5 (2.8–9.8)	7.9 (4.1–17.6)	4.7 (2.9–10.9)	7.5 (3.7–19.7)	3.8 (2.5–6.8)	<0.001
Glucose, median mmol/L	5.8 (5.3–6.7)	6.5 (5.8–7.9)	5.9 (5.4–6.7)	6.1 (5.5–7.3)	5.6 (5.2–6.4)	<0.001

Baseline characteristics of the included patients. Numbers in parenthesis for continuous data are the 25th and 75th percentile. Data from WESTCOR.

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