Table 2 Open in new tab Patient...

	Age in years, mean (range)/ mean ± SD	Sex, % female	Ventricle type, % left	Age in years at Fontan completion, mean (range)/ mean ± SD	Fontan type ECC/ICC/ICT/ KW/ LT/AP/AVA/O in %	Open fenestration in %
Studies including children only:
Jacobsen^17,23	10.5 (9–12)	55	43	3.1	93 ECC, 7 LT	45%
Sutherland (home)²⁵	15 ± 2.7	45	–	–	100 ECC	–
Sutherland (hospital)²⁵	16 ± 2.5	33	–	–	67 ECC, 17 LT, 17 AP	–
Wittekind²⁶	12 ± 2.8	60	50	3.5	50 ECC, 50 LT	–
Hedlund^28,39	14.2 ± 3.2	47	–	2.4 (1.1–6.4)	–	0%
Laohachai³⁰	16 ± 2	48	57	5 ± 2 (3–9)	–	0%
Longmuir²⁴	9.1	41	33	2.9	87 ECC, 13 LT	–
Opocher¹⁹	8.7 ± 0.6	10	70	1.7 (1–3)	–	–
Studies including adults only:
Fritz²¹	28.6 (24.7–36.5)	50	86	6.3 (4.0–9.9)	9 AP, 8 AVA, 25 TCPCu	–
Wu³¹	28.8 (25.7–45.5)	45	73	7.8 (3.9–16.5)	9 ECC, 64 LT, 27 AP	18%
Cordina³²	31 ± 4	18	82	11 ± 4	18 ECC, 45 ICC, 36 AP	9%
Lichtman²⁰	28	100	100	26	100 AP	–
Studies including children and adults:
Ait Ali¹⁸	17.5 (10.4–22.8)	13	43	3.96 (0.8–7.4)	71 ECC, 7 ICC, 14 ICT, 7 KW	–
Duppen⁹^,^13–16	15 ± 3	60	69	3 (2.5–4)	42 ECC, 54 ILT, 4 O	–
Brassard²²	16 ± 5	43	100	–	–	–
Minamisawa²⁹	19 ± 4	55	82	14 ± 6	100 AP	–
Balfour²⁷	19.8	NP	100	–	–	–

Age in years, mean (range)/ mean ± SD

Sex, % female

Ventricle type, % left

Age in years at Fontan completion, mean (range)/ mean ± SD

Fontan type ECC/ICC/ICT/ KW/ LT/AP/AVA/O in %

Open fenestration in %

Studies including children only:

Jacobsen^17,23

10.5 (9–12)

3.1

93 ECC, 7 LT

45%

Sutherland (home)²⁵

15 ± 2.7

–

100 ECC

–

Sutherland (hospital)²⁵

16 ± 2.5

–

67 ECC, 17 LT, 17 AP

–

Wittekind²⁶

12 ± 2.8

3.5

50 ECC, 50 LT

–

Hedlund^28,39

14.2 ± 3.2

–

2.4 (1.1–6.4)

–

Laohachai³⁰

16 ± 2

5 ± 2 (3–9)

–

Longmuir²⁴

9.1

2.9

87 ECC, 13 LT

–

Opocher¹⁹

8.7 ± 0.6

1.7 (1–3)

–

Studies including adults only:

Fritz²¹

28.6 (24.7–36.5)

6.3 (4.0–9.9)

9 AP, 8 AVA, 25 TCPCu

–

Wu³¹

28.8 (25.7–45.5)

7.8 (3.9–16.5)

9 ECC, 64 LT, 27 AP

18%

Cordina³²

31 ± 4

11 ± 4

18 ECC, 45 ICC, 36 AP

Lichtman²⁰

100

100 AP

–

Studies including children and adults:

Ait Ali¹⁸

17.5 (10.4–22.8)

3.96 (0.8–7.4)

71 ECC, 7 ICC, 14 ICT, 7 KW

–

Duppen⁹^,^13–16

15 ± 3

3 (2.5–4)

42 ECC, 54 ILT, 4 O

–

Brassard²²

16 ± 5

100

–

Minamisawa²⁹

19 ± 4

14 ± 6

100 AP

–

Balfour²⁷

19.8

100

–

	Age in years, mean (range)/ mean ± SD	Sex, % female	Ventricle type, % left	Age in years at Fontan completion, mean (range)/ mean ± SD	Fontan type ECC/ICC/ICT/ KW/ LT/AP/AVA/O in %	Open fenestration in %
Studies including children only:
Jacobsen^17,23	10.5 (9–12)	55	43	3.1	93 ECC, 7 LT	45%
Sutherland (home)²⁵	15 ± 2.7	45	–	–	100 ECC	–
Sutherland (hospital)²⁵	16 ± 2.5	33	–	–	67 ECC, 17 LT, 17 AP	–
Wittekind²⁶	12 ± 2.8	60	50	3.5	50 ECC, 50 LT	–
Hedlund^28,39	14.2 ± 3.2	47	–	2.4 (1.1–6.4)	–	0%
Laohachai³⁰	16 ± 2	48	57	5 ± 2 (3–9)	–	0%
Longmuir²⁴	9.1	41	33	2.9	87 ECC, 13 LT	–
Opocher¹⁹	8.7 ± 0.6	10	70	1.7 (1–3)	–	–
Studies including adults only:
Fritz²¹	28.6 (24.7–36.5)	50	86	6.3 (4.0–9.9)	9 AP, 8 AVA, 25 TCPCu	–
Wu³¹	28.8 (25.7–45.5)	45	73	7.8 (3.9–16.5)	9 ECC, 64 LT, 27 AP	18%
Cordina³²	31 ± 4	18	82	11 ± 4	18 ECC, 45 ICC, 36 AP	9%
Lichtman²⁰	28	100	100	26	100 AP	–
Studies including children and adults:
Ait Ali¹⁸	17.5 (10.4–22.8)	13	43	3.96 (0.8–7.4)	71 ECC, 7 ICC, 14 ICT, 7 KW	–
Duppen⁹^,^13–16	15 ± 3	60	69	3 (2.5–4)	42 ECC, 54 ILT, 4 O	–
Brassard²²	16 ± 5	43	100	–	–	–
Minamisawa²⁹	19 ± 4	55	82	14 ± 6	100 AP	–
Balfour²⁷	19.8	NP	100	–	–	–

Table 2

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Patient characteristics.

	Age in years, mean (range)/ mean ± SD	Sex, % female	Ventricle type, % left	Age in years at Fontan completion, mean (range)/ mean ± SD	Fontan type ECC/ICC/ICT/ KW/ LT/AP/AVA/O in %	Open fenestration in %
Studies including children only:
Jacobsen^17,23	10.5 (9–12)	55	43	3.1	93 ECC, 7 LT	45%
Sutherland (home)²⁵	15 ± 2.7	45	–	–	100 ECC	–
Sutherland (hospital)²⁵	16 ± 2.5	33	–	–	67 ECC, 17 LT, 17 AP	–
Wittekind²⁶	12 ± 2.8	60	50	3.5	50 ECC, 50 LT	–
Hedlund^28,39	14.2 ± 3.2	47	–	2.4 (1.1–6.4)	–	0%
Laohachai³⁰	16 ± 2	48	57	5 ± 2 (3–9)	–	0%
Longmuir²⁴	9.1	41	33	2.9	87 ECC, 13 LT	–
Opocher¹⁹	8.7 ± 0.6	10	70	1.7 (1–3)	–	–
Studies including adults only:
Fritz²¹	28.6 (24.7–36.5)	50	86	6.3 (4.0–9.9)	9 AP, 8 AVA, 25 TCPCu	–
Wu³¹	28.8 (25.7–45.5)	45	73	7.8 (3.9–16.5)	9 ECC, 64 LT, 27 AP	18%
Cordina³²	31 ± 4	18	82	11 ± 4	18 ECC, 45 ICC, 36 AP	9%
Lichtman²⁰	28	100	100	26	100 AP	–
Studies including children and adults:
Ait Ali¹⁸	17.5 (10.4–22.8)	13	43	3.96 (0.8–7.4)	71 ECC, 7 ICC, 14 ICT, 7 KW	–
Duppen⁹^,^13–16	15 ± 3	60	69	3 (2.5–4)	42 ECC, 54 ILT, 4 O	–
Brassard²²	16 ± 5	43	100	–	–	–
Minamisawa²⁹	19 ± 4	55	82	14 ± 6	100 AP	–
Balfour²⁷	19.8	NP	100	–	–	–

	Age in years, mean (range)/ mean ± SD	Sex, % female	Ventricle type, % left	Age in years at Fontan completion, mean (range)/ mean ± SD	Fontan type ECC/ICC/ICT/ KW/ LT/AP/AVA/O in %	Open fenestration in %
Studies including children only:
Jacobsen^17,23	10.5 (9–12)	55	43	3.1	93 ECC, 7 LT	45%
Sutherland (home)²⁵	15 ± 2.7	45	–	–	100 ECC	–
Sutherland (hospital)²⁵	16 ± 2.5	33	–	–	67 ECC, 17 LT, 17 AP	–
Wittekind²⁶	12 ± 2.8	60	50	3.5	50 ECC, 50 LT	–
Hedlund^28,39	14.2 ± 3.2	47	–	2.4 (1.1–6.4)	–	0%
Laohachai³⁰	16 ± 2	48	57	5 ± 2 (3–9)	–	0%
Longmuir²⁴	9.1	41	33	2.9	87 ECC, 13 LT	–
Opocher¹⁹	8.7 ± 0.6	10	70	1.7 (1–3)	–	–
Studies including adults only:
Fritz²¹	28.6 (24.7–36.5)	50	86	6.3 (4.0–9.9)	9 AP, 8 AVA, 25 TCPCu	–
Wu³¹	28.8 (25.7–45.5)	45	73	7.8 (3.9–16.5)	9 ECC, 64 LT, 27 AP	18%
Cordina³²	31 ± 4	18	82	11 ± 4	18 ECC, 45 ICC, 36 AP	9%
Lichtman²⁰	28	100	100	26	100 AP	–
Studies including children and adults:
Ait Ali¹⁸	17.5 (10.4–22.8)	13	43	3.96 (0.8–7.4)	71 ECC, 7 ICC, 14 ICT, 7 KW	–
Duppen⁹^,^13–16	15 ± 3	60	69	3 (2.5–4)	42 ECC, 54 ILT, 4 O	–
Brassard²²	16 ± 5	43	100	–	–	–
Minamisawa²⁹	19 ± 4	55	82	14 ± 6	100 AP	–
Balfour²⁷	19.8	NP	100	–	–	–

AP: atriopulmonary connection; AVA: atrioventricular anastomosis; ECC: extracardiac conduit; ICC: intracardiac conduit; ICT: intracardiac tunnel; KW: Kawashima Fontan; LT: lateral tunnel Fontan; O: other; SD: standard deviation; TCPCu: Total cavopulmonary connection undefined.

The symbol ‘-' indicates not mentioned in the article. Duppen et al. studies included Fontan patients and tetralogy of Fallot patients. The mean age and percentage of female patients is a mean of both patient groups together. All characteristics are extracted from the articles. Some articles included the dropouts in the patient characteristics, and some did not.

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