Crude and adjusted risk of DKD progression, according to the quartiles of serum Hb concentration
| Models . | Serum Hb concentration . | . | |||
|---|---|---|---|---|---|
| HR (95% CI) . | Quartile 1 . | Quartile 2 . | Quartile 3 . | Quartile 4 . | P for trend . |
| ≤12.0 g/dL . | 12.1–13.3 g/dL . | 13.4–14.5 g/dL . | ≥14.6 g/dL . | ||
| Model1 | 3.81 (2.14–6.80) | 2.34 (1.29–4.24) | 1.48 (0.78–2.80) | Ref. | <0.001 |
| Model 2 | 4.37 (2.28–8.37) | 2.64 (1.38–5.04) | 1.61 (0.81–3.18) | Ref. | <0.001 |
| Model 3 | 2.74 (1.26–5.97) | 2.33 (1.07–5.75) | 1.46 (0.71–3.64) | Ref. | <0.001 |
| Models . | Serum Hb concentration . | . | |||
|---|---|---|---|---|---|
| HR (95% CI) . | Quartile 1 . | Quartile 2 . | Quartile 3 . | Quartile 4 . | P for trend . |
| ≤12.0 g/dL . | 12.1–13.3 g/dL . | 13.4–14.5 g/dL . | ≥14.6 g/dL . | ||
| Model1 | 3.81 (2.14–6.80) | 2.34 (1.29–4.24) | 1.48 (0.78–2.80) | Ref. | <0.001 |
| Model 2 | 4.37 (2.28–8.37) | 2.64 (1.38–5.04) | 1.61 (0.81–3.18) | Ref. | <0.001 |
| Model 3 | 2.74 (1.26–5.97) | 2.33 (1.07–5.75) | 1.46 (0.71–3.64) | Ref. | <0.001 |
HR (95% CI) and P-values were determined for demographic and laboratory characteristics by univariable and multivariable Cox proportional models.
Model 1: univariable.
Model 2: adjusted for age and gender.
Model 3: adjusted for known risk factors of DKD progression (age, gender, BMI, diabetic duration, systolic BP, Hb A1c, eGFR, UACR and RAS blocker use).
Crude and adjusted risk of DKD progression, according to the quartiles of serum Hb concentration
| Models . | Serum Hb concentration . | . | |||
|---|---|---|---|---|---|
| HR (95% CI) . | Quartile 1 . | Quartile 2 . | Quartile 3 . | Quartile 4 . | P for trend . |
| ≤12.0 g/dL . | 12.1–13.3 g/dL . | 13.4–14.5 g/dL . | ≥14.6 g/dL . | ||
| Model1 | 3.81 (2.14–6.80) | 2.34 (1.29–4.24) | 1.48 (0.78–2.80) | Ref. | <0.001 |
| Model 2 | 4.37 (2.28–8.37) | 2.64 (1.38–5.04) | 1.61 (0.81–3.18) | Ref. | <0.001 |
| Model 3 | 2.74 (1.26–5.97) | 2.33 (1.07–5.75) | 1.46 (0.71–3.64) | Ref. | <0.001 |
| Models . | Serum Hb concentration . | . | |||
|---|---|---|---|---|---|
| HR (95% CI) . | Quartile 1 . | Quartile 2 . | Quartile 3 . | Quartile 4 . | P for trend . |
| ≤12.0 g/dL . | 12.1–13.3 g/dL . | 13.4–14.5 g/dL . | ≥14.6 g/dL . | ||
| Model1 | 3.81 (2.14–6.80) | 2.34 (1.29–4.24) | 1.48 (0.78–2.80) | Ref. | <0.001 |
| Model 2 | 4.37 (2.28–8.37) | 2.64 (1.38–5.04) | 1.61 (0.81–3.18) | Ref. | <0.001 |
| Model 3 | 2.74 (1.26–5.97) | 2.33 (1.07–5.75) | 1.46 (0.71–3.64) | Ref. | <0.001 |
HR (95% CI) and P-values were determined for demographic and laboratory characteristics by univariable and multivariable Cox proportional models.
Model 1: univariable.
Model 2: adjusted for age and gender.
Model 3: adjusted for known risk factors of DKD progression (age, gender, BMI, diabetic duration, systolic BP, Hb A1c, eGFR, UACR and RAS blocker use).
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