| T1 . | %(95%CI) (N = 106) . | T2 . | %(95%CI) (N = 93) . | T3 . | %(95%CI) (N = 88) . |
|---|---|---|---|---|---|
| Pain | 46 (37–56) | Pain | 36 (27–46) | Fatigue | 33 (24–43) |
| Disturbed sleep | 41 (32–50) | Dry mouth | 36 (27–46) | Numbness or tingling | 32 (23–42) |
| Distress | 38 (29–47) | Disturbed sleep | 33 (24–43) | Pain | 31 (22–41) |
| Dry mouth | 35 (27–44) | Fatigue | 33 (24–43) | Distress | 24 (16–34) |
| Sadness | 32 (24–42) | Distress | 32 (23–42) | Drowsiness | 24 (16–34) |
| Depression | 30 (22–40) | Drowsiness | 31 (22–41) | Dry mouth | 23 (15–33) |
| Lack of appetite | 28 (21–38) | Sadness | 26 (18–35) | Disturbed sleep | 18 (11–28) |
| Drowsiness | 26 (19–36) | Depression | 21 (14–31) | Lack of appetite | 18 (11–28) |
| Fatigue | 25 (18–35) | Lack of appetite | 20 (13–30) | Sadness | 17 (11–26) |
| Shortness of breath | 22 (15–31) | Shortness of breath | 16 (10–25) | Shortness of breath | 16 (10–25) |
| Numbness or tingling | 19 (13–27) | Numbness or tingling | 15 (9–24) | Difficulty remembering | 14 (8–23) |
| Difficulty remembering | 12 (7–20) | Nausea | 11 (6–19) | Depression | 10 (5–19) |
| Nausea | 7 (3–13) | Difficulty remembering | 9 (4–16) | Nausea | 6 (2–13) |
| Vomiting | 3 (1–8) | Vomiting | 5 (2–12) | Vomiting | 3 (1–10) |
| T1 . | %(95%CI) (N = 106) . | T2 . | %(95%CI) (N = 93) . | T3 . | %(95%CI) (N = 88) . |
|---|---|---|---|---|---|
| Pain | 46 (37–56) | Pain | 36 (27–46) | Fatigue | 33 (24–43) |
| Disturbed sleep | 41 (32–50) | Dry mouth | 36 (27–46) | Numbness or tingling | 32 (23–42) |
| Distress | 38 (29–47) | Disturbed sleep | 33 (24–43) | Pain | 31 (22–41) |
| Dry mouth | 35 (27–44) | Fatigue | 33 (24–43) | Distress | 24 (16–34) |
| Sadness | 32 (24–42) | Distress | 32 (23–42) | Drowsiness | 24 (16–34) |
| Depression | 30 (22–40) | Drowsiness | 31 (22–41) | Dry mouth | 23 (15–33) |
| Lack of appetite | 28 (21–38) | Sadness | 26 (18–35) | Disturbed sleep | 18 (11–28) |
| Drowsiness | 26 (19–36) | Depression | 21 (14–31) | Lack of appetite | 18 (11–28) |
| Fatigue | 25 (18–35) | Lack of appetite | 20 (13–30) | Sadness | 17 (11–26) |
| Shortness of breath | 22 (15–31) | Shortness of breath | 16 (10–25) | Shortness of breath | 16 (10–25) |
| Numbness or tingling | 19 (13–27) | Numbness or tingling | 15 (9–24) | Difficulty remembering | 14 (8–23) |
| Difficulty remembering | 12 (7–20) | Nausea | 11 (6–19) | Depression | 10 (5–19) |
| Nausea | 7 (3–13) | Difficulty remembering | 9 (4–16) | Nausea | 6 (2–13) |
| Vomiting | 3 (1–8) | Vomiting | 5 (2–12) | Vomiting | 3 (1–10) |
Abbreviations: MDASI, MD Anderson Symptom Inventory; PHQ-9, Patient Health Questionnaire-9.
Depression was assessed using the Patient Health Questionnaire-9. Other symptoms were assessed using the MDASI.
Data show the proportion of patients reporting scores of ≥4 on each MDASI symptom. Definition of depression was described in the text.
| T1 . | %(95%CI) (N = 106) . | T2 . | %(95%CI) (N = 93) . | T3 . | %(95%CI) (N = 88) . |
|---|---|---|---|---|---|
| Pain | 46 (37–56) | Pain | 36 (27–46) | Fatigue | 33 (24–43) |
| Disturbed sleep | 41 (32–50) | Dry mouth | 36 (27–46) | Numbness or tingling | 32 (23–42) |
| Distress | 38 (29–47) | Disturbed sleep | 33 (24–43) | Pain | 31 (22–41) |
| Dry mouth | 35 (27–44) | Fatigue | 33 (24–43) | Distress | 24 (16–34) |
| Sadness | 32 (24–42) | Distress | 32 (23–42) | Drowsiness | 24 (16–34) |
| Depression | 30 (22–40) | Drowsiness | 31 (22–41) | Dry mouth | 23 (15–33) |
| Lack of appetite | 28 (21–38) | Sadness | 26 (18–35) | Disturbed sleep | 18 (11–28) |
| Drowsiness | 26 (19–36) | Depression | 21 (14–31) | Lack of appetite | 18 (11–28) |
| Fatigue | 25 (18–35) | Lack of appetite | 20 (13–30) | Sadness | 17 (11–26) |
| Shortness of breath | 22 (15–31) | Shortness of breath | 16 (10–25) | Shortness of breath | 16 (10–25) |
| Numbness or tingling | 19 (13–27) | Numbness or tingling | 15 (9–24) | Difficulty remembering | 14 (8–23) |
| Difficulty remembering | 12 (7–20) | Nausea | 11 (6–19) | Depression | 10 (5–19) |
| Nausea | 7 (3–13) | Difficulty remembering | 9 (4–16) | Nausea | 6 (2–13) |
| Vomiting | 3 (1–8) | Vomiting | 5 (2–12) | Vomiting | 3 (1–10) |
| T1 . | %(95%CI) (N = 106) . | T2 . | %(95%CI) (N = 93) . | T3 . | %(95%CI) (N = 88) . |
|---|---|---|---|---|---|
| Pain | 46 (37–56) | Pain | 36 (27–46) | Fatigue | 33 (24–43) |
| Disturbed sleep | 41 (32–50) | Dry mouth | 36 (27–46) | Numbness or tingling | 32 (23–42) |
| Distress | 38 (29–47) | Disturbed sleep | 33 (24–43) | Pain | 31 (22–41) |
| Dry mouth | 35 (27–44) | Fatigue | 33 (24–43) | Distress | 24 (16–34) |
| Sadness | 32 (24–42) | Distress | 32 (23–42) | Drowsiness | 24 (16–34) |
| Depression | 30 (22–40) | Drowsiness | 31 (22–41) | Dry mouth | 23 (15–33) |
| Lack of appetite | 28 (21–38) | Sadness | 26 (18–35) | Disturbed sleep | 18 (11–28) |
| Drowsiness | 26 (19–36) | Depression | 21 (14–31) | Lack of appetite | 18 (11–28) |
| Fatigue | 25 (18–35) | Lack of appetite | 20 (13–30) | Sadness | 17 (11–26) |
| Shortness of breath | 22 (15–31) | Shortness of breath | 16 (10–25) | Shortness of breath | 16 (10–25) |
| Numbness or tingling | 19 (13–27) | Numbness or tingling | 15 (9–24) | Difficulty remembering | 14 (8–23) |
| Difficulty remembering | 12 (7–20) | Nausea | 11 (6–19) | Depression | 10 (5–19) |
| Nausea | 7 (3–13) | Difficulty remembering | 9 (4–16) | Nausea | 6 (2–13) |
| Vomiting | 3 (1–8) | Vomiting | 5 (2–12) | Vomiting | 3 (1–10) |
Abbreviations: MDASI, MD Anderson Symptom Inventory; PHQ-9, Patient Health Questionnaire-9.
Depression was assessed using the Patient Health Questionnaire-9. Other symptoms were assessed using the MDASI.
Data show the proportion of patients reporting scores of ≥4 on each MDASI symptom. Definition of depression was described in the text.
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