Table 2: Open in new tab GO annotations...

Human Gene

Aspect

InterPro2GO

Compara

PAINT

SOD1

Metal ion binding

SOD activity, chaperone binding

SOD activity, zinc ion binding, copper ion binding

Nucleus, cytoplasm, mitochondrion, neuronal cell body

Nucleus, cytosol, mitochondrion, extracellular region

Superoxide metabolic process, oxidation-reduction process,

Activation of MAPK activity, response to reactive oxygen species, ovarian follicle development, myeloid cell homeostasis, retina homeostasis, anti-apoptosis, spermatogenesis, aging, locomotory behavior, response to drug, 31 others

Removal of superoxide radicals

CCS

Metal ion binding

SOD copper chaperone activity, zinc ion binding, copper ion binding, NOT SOD activity

Cytosol, mitochondrion, nucleus

Superoxide metabolic process, oxidation-reduction process, metal ion transport

Removal of superoxide radicals, intracellular copper ion transport

PGM1

Magnesium ion binding, intramolecular transferase activity, phosphotransferases

Phosphoglucomutase activity

Cytosol

Carbohydrate metabolic process

Glycogen biosynthetic process, glucose-1-phosphate metabolic process

PGM5

Magnesium ion binding, intramolecular transferase activity, phosphotransferases

NOT phosphoglucomutase activity

Spot adherens junction, Z disc, focal adhesion

Cytosol, spot adherens junction, Z disc, stress fiber, focal adhesion, intercalated disc

Carbohydrate metabolic process

NOT glycogen biosynthetic process, NOT glucose-1-phosphate metabolic process

Table 2:

Open in new tab

GO annotations inferred for different human genes by InterPro2GO, Compara and PAINT

Human Gene	Aspect	InterPro2GO	Compara	PAINT
SOD1	MF	Metal ion binding	SOD activity, chaperone binding	SOD activity, zinc ion binding, copper ion binding
	CC		Nucleus, cytoplasm, mitochondrion, neuronal cell body	Nucleus, cytosol, mitochondrion, extracellular region
	BP	Superoxide metabolic process, oxidation-reduction process,	Activation of MAPK activity, response to reactive oxygen species, ovarian follicle development, myeloid cell homeostasis, retina homeostasis, anti-apoptosis, spermatogenesis, aging, locomotory behavior, response to drug, 31 others	Removal of superoxide radicals
CCS	MF	Metal ion binding		SOD copper chaperone activity, zinc ion binding, copper ion binding, NOT SOD activity
	CC			Cytosol, mitochondrion, nucleus
	BP	Superoxide metabolic process, oxidation-reduction process, metal ion transport		Removal of superoxide radicals, intracellular copper ion transport
PGM1	MF	Magnesium ion binding, intramolecular transferase activity, phosphotransferases		Phosphoglucomutase activity
	CC			Cytosol
	BP	Carbohydrate metabolic process		Glycogen biosynthetic process, glucose-1-phosphate metabolic process
PGM5	MF	Magnesium ion binding, intramolecular transferase activity, phosphotransferases		NOT phosphoglucomutase activity
	CC		Spot adherens junction, Z disc, focal adhesion	Cytosol, spot adherens junction, Z disc, stress fiber, focal adhesion, intercalated disc
	BP	Carbohydrate metabolic process		NOT glycogen biosynthetic process, NOT glucose-1-phosphate metabolic process

Human Gene	Aspect	InterPro2GO	Compara	PAINT
SOD1	MF	Metal ion binding	SOD activity, chaperone binding	SOD activity, zinc ion binding, copper ion binding
	CC		Nucleus, cytoplasm, mitochondrion, neuronal cell body	Nucleus, cytosol, mitochondrion, extracellular region
	BP	Superoxide metabolic process, oxidation-reduction process,	Activation of MAPK activity, response to reactive oxygen species, ovarian follicle development, myeloid cell homeostasis, retina homeostasis, anti-apoptosis, spermatogenesis, aging, locomotory behavior, response to drug, 31 others	Removal of superoxide radicals
CCS	MF	Metal ion binding		SOD copper chaperone activity, zinc ion binding, copper ion binding, NOT SOD activity
	CC			Cytosol, mitochondrion, nucleus
	BP	Superoxide metabolic process, oxidation-reduction process, metal ion transport		Removal of superoxide radicals, intracellular copper ion transport
PGM1	MF	Magnesium ion binding, intramolecular transferase activity, phosphotransferases		Phosphoglucomutase activity
	CC			Cytosol
	BP	Carbohydrate metabolic process		Glycogen biosynthetic process, glucose-1-phosphate metabolic process
PGM5	MF	Magnesium ion binding, intramolecular transferase activity, phosphotransferases		NOT phosphoglucomutase activity
	CC		Spot adherens junction, Z disc, focal adhesion	Cytosol, spot adherens junction, Z disc, stress fiber, focal adhesion, intercalated disc
	BP	Carbohydrate metabolic process		NOT glycogen biosynthetic process, NOT glucose-1-phosphate metabolic process

These are arranged by aspect in the GO: MF, CC and BP.

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