Morbidity and Mortality Risks of Aspergillosis in At-Risk Patients (Healthcare Cost and Utilization Project, 2018), United States
| Diagnosis . | Average Cost of Visit (in $1000) . | Average Length of Stay (Days) . | Infection, No., Rate per 100 000 . | Deaths, No., % Infected . | Relative Risk of Mortality (95% CI) . | Population, No. . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| – . | + . | Ratio . | – . | + . | Ratio . | |||||
| All visits with at-risk diagnoses | 30.43 | 101.02 | 3.41 | 5.53 | 13.40 | 2.59 | 12 030 67.53 | 1240 10.31 | 3.19 (3.03–3.36) | 17 813 520 |
| Cancer | 77.68 | 307.23 | 3.96 | 6.00 | 17.96 | 2.99 | 3190 114.56 | 715 22.41 | 2.91 (2.72–3.11) | 2 784 530 |
| Leukemia | 108.71 | 373.40 | 3.43 | 8.06 | 22.34 | 2.77 | 2205 823.08 | 285 12.93 | 2.46 (2.21–2.74) | 267 895 |
| Lung, trachea, bronchus | 69.18 | 146.82 | 2.12 | 6.00 | 9.86 | 1.64 | 670 169.77 | 110 16.42 | 1.90 (1.60–2.25) | 394 645 |
| Non-Hodgkin lymphoma | 89.38 | 364.86 | 4.08 | 6.54 | 18.87 | 2.89 | 555 278.80 | 115 20.72 | 4.43 (3.75–5.20) | 199 065 |
| Cystic fibrosis | 51.40 | 69.38 | 1.35 | 9.39 | 12.11 | 1.29 | 1800 5939.61 | 20 1.11 | 1.05 (.67–1.63) | 282 645 |
| Influenza | 55.59 | 275.87 | 4.96 | 5.43 | 17.18 | 3.16 | 575 152.14 | 85 14.78 | 4.23 (3.46–5.13) | 377 950 |
| Transplant history | 35.42 | 113.04 | 3.19 | 5.41 | 14.56 | 2.69 | 1170 444.65 | 135 11.54 | 4.82 (4.10–5.63) | 282 645 |
| Bone marrow | 48.39 | 72.19 | 1.49 | 6.83 | 11.97 | 1.75 | 170 781.25 | 40 23.53 | 5.80 (4.35–7.57) | 1005 |
| Kidney | 29.06 | 120.19 | 4.14 | 4.90 | 12.95 | 2.64 | 190 159.80 | 20 10.53 | 5.54 (3.63–8.27) | 118 895 |
| Lung | 36.82 | 63.47 | 1.72 | 5.94 | 14.56 | 2.69 | 205 1851.02 | a | 1.06 (.45–2.44) | 11 075 |
| Stem cell | 54.29 | 153.34 | 2.83 | 6.85 | 17.64 | 2.57 | 390 1015.76 | 60 15.38 | 3.49 (2.74–4.40) | 38 395 |
| Transplant complications | 68.62 | 206.00 | 3.00 | 8.39 | 21.91 | 2.61 | 1350 1046.07 | 205 15.19 | 4.34 (3.81–4.94) | 142 875 |
| Bone marrow | 98.91 | 321.76 | 3.25 | 11.88 | 36.85 | 3.10 | 65 2260.87 | a | 2.76 (1.51–4.77) | 2900 |
| Kidney | 47.33 | 119.94 | 2.53 | 7.01 | 16.11 | 2.30 | 225 285.88 | 40 17.78 | 6.97 (5.21–9.17) | 85 650 |
| Lung | 112.28 | 144.78 | 1.72 | 8.75 | 16.39 | 1.87 | 590 6190.98 | 65 11.02 | 2.37 (1.85–3.02) | 11 325 |
| Stem cell | 133.45 | 303.81 | 2.28 | 16.67 | 29.26 | 1.75 | 325 3296.15 | 70 21.54 | 2.42 (1.94–2.98) | 9860 |
| Diagnosis . | Average Cost of Visit (in $1000) . | Average Length of Stay (Days) . | Infection, No., Rate per 100 000 . | Deaths, No., % Infected . | Relative Risk of Mortality (95% CI) . | Population, No. . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| – . | + . | Ratio . | – . | + . | Ratio . | |||||
| All visits with at-risk diagnoses | 30.43 | 101.02 | 3.41 | 5.53 | 13.40 | 2.59 | 12 030 67.53 | 1240 10.31 | 3.19 (3.03–3.36) | 17 813 520 |
| Cancer | 77.68 | 307.23 | 3.96 | 6.00 | 17.96 | 2.99 | 3190 114.56 | 715 22.41 | 2.91 (2.72–3.11) | 2 784 530 |
| Leukemia | 108.71 | 373.40 | 3.43 | 8.06 | 22.34 | 2.77 | 2205 823.08 | 285 12.93 | 2.46 (2.21–2.74) | 267 895 |
| Lung, trachea, bronchus | 69.18 | 146.82 | 2.12 | 6.00 | 9.86 | 1.64 | 670 169.77 | 110 16.42 | 1.90 (1.60–2.25) | 394 645 |
| Non-Hodgkin lymphoma | 89.38 | 364.86 | 4.08 | 6.54 | 18.87 | 2.89 | 555 278.80 | 115 20.72 | 4.43 (3.75–5.20) | 199 065 |
| Cystic fibrosis | 51.40 | 69.38 | 1.35 | 9.39 | 12.11 | 1.29 | 1800 5939.61 | 20 1.11 | 1.05 (.67–1.63) | 282 645 |
| Influenza | 55.59 | 275.87 | 4.96 | 5.43 | 17.18 | 3.16 | 575 152.14 | 85 14.78 | 4.23 (3.46–5.13) | 377 950 |
| Transplant history | 35.42 | 113.04 | 3.19 | 5.41 | 14.56 | 2.69 | 1170 444.65 | 135 11.54 | 4.82 (4.10–5.63) | 282 645 |
| Bone marrow | 48.39 | 72.19 | 1.49 | 6.83 | 11.97 | 1.75 | 170 781.25 | 40 23.53 | 5.80 (4.35–7.57) | 1005 |
| Kidney | 29.06 | 120.19 | 4.14 | 4.90 | 12.95 | 2.64 | 190 159.80 | 20 10.53 | 5.54 (3.63–8.27) | 118 895 |
| Lung | 36.82 | 63.47 | 1.72 | 5.94 | 14.56 | 2.69 | 205 1851.02 | a | 1.06 (.45–2.44) | 11 075 |
| Stem cell | 54.29 | 153.34 | 2.83 | 6.85 | 17.64 | 2.57 | 390 1015.76 | 60 15.38 | 3.49 (2.74–4.40) | 38 395 |
| Transplant complications | 68.62 | 206.00 | 3.00 | 8.39 | 21.91 | 2.61 | 1350 1046.07 | 205 15.19 | 4.34 (3.81–4.94) | 142 875 |
| Bone marrow | 98.91 | 321.76 | 3.25 | 11.88 | 36.85 | 3.10 | 65 2260.87 | a | 2.76 (1.51–4.77) | 2900 |
| Kidney | 47.33 | 119.94 | 2.53 | 7.01 | 16.11 | 2.30 | 225 285.88 | 40 17.78 | 6.97 (5.21–9.17) | 85 650 |
| Lung | 112.28 | 144.78 | 1.72 | 8.75 | 16.39 | 1.87 | 590 6190.98 | 65 11.02 | 2.37 (1.85–3.02) | 11 325 |
| Stem cell | 133.45 | 303.81 | 2.28 | 16.67 | 29.26 | 1.75 | 325 3296.15 | 70 21.54 | 2.42 (1.94–2.98) | 9860 |
Abbreviation: CI, confidence interval.
Estimates suppressed with Healthcare Cost and Utilization Project protocols.
Morbidity and Mortality Risks of Aspergillosis in At-Risk Patients (Healthcare Cost and Utilization Project, 2018), United States
| Diagnosis . | Average Cost of Visit (in $1000) . | Average Length of Stay (Days) . | Infection, No., Rate per 100 000 . | Deaths, No., % Infected . | Relative Risk of Mortality (95% CI) . | Population, No. . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| – . | + . | Ratio . | – . | + . | Ratio . | |||||
| All visits with at-risk diagnoses | 30.43 | 101.02 | 3.41 | 5.53 | 13.40 | 2.59 | 12 030 67.53 | 1240 10.31 | 3.19 (3.03–3.36) | 17 813 520 |
| Cancer | 77.68 | 307.23 | 3.96 | 6.00 | 17.96 | 2.99 | 3190 114.56 | 715 22.41 | 2.91 (2.72–3.11) | 2 784 530 |
| Leukemia | 108.71 | 373.40 | 3.43 | 8.06 | 22.34 | 2.77 | 2205 823.08 | 285 12.93 | 2.46 (2.21–2.74) | 267 895 |
| Lung, trachea, bronchus | 69.18 | 146.82 | 2.12 | 6.00 | 9.86 | 1.64 | 670 169.77 | 110 16.42 | 1.90 (1.60–2.25) | 394 645 |
| Non-Hodgkin lymphoma | 89.38 | 364.86 | 4.08 | 6.54 | 18.87 | 2.89 | 555 278.80 | 115 20.72 | 4.43 (3.75–5.20) | 199 065 |
| Cystic fibrosis | 51.40 | 69.38 | 1.35 | 9.39 | 12.11 | 1.29 | 1800 5939.61 | 20 1.11 | 1.05 (.67–1.63) | 282 645 |
| Influenza | 55.59 | 275.87 | 4.96 | 5.43 | 17.18 | 3.16 | 575 152.14 | 85 14.78 | 4.23 (3.46–5.13) | 377 950 |
| Transplant history | 35.42 | 113.04 | 3.19 | 5.41 | 14.56 | 2.69 | 1170 444.65 | 135 11.54 | 4.82 (4.10–5.63) | 282 645 |
| Bone marrow | 48.39 | 72.19 | 1.49 | 6.83 | 11.97 | 1.75 | 170 781.25 | 40 23.53 | 5.80 (4.35–7.57) | 1005 |
| Kidney | 29.06 | 120.19 | 4.14 | 4.90 | 12.95 | 2.64 | 190 159.80 | 20 10.53 | 5.54 (3.63–8.27) | 118 895 |
| Lung | 36.82 | 63.47 | 1.72 | 5.94 | 14.56 | 2.69 | 205 1851.02 | a | 1.06 (.45–2.44) | 11 075 |
| Stem cell | 54.29 | 153.34 | 2.83 | 6.85 | 17.64 | 2.57 | 390 1015.76 | 60 15.38 | 3.49 (2.74–4.40) | 38 395 |
| Transplant complications | 68.62 | 206.00 | 3.00 | 8.39 | 21.91 | 2.61 | 1350 1046.07 | 205 15.19 | 4.34 (3.81–4.94) | 142 875 |
| Bone marrow | 98.91 | 321.76 | 3.25 | 11.88 | 36.85 | 3.10 | 65 2260.87 | a | 2.76 (1.51–4.77) | 2900 |
| Kidney | 47.33 | 119.94 | 2.53 | 7.01 | 16.11 | 2.30 | 225 285.88 | 40 17.78 | 6.97 (5.21–9.17) | 85 650 |
| Lung | 112.28 | 144.78 | 1.72 | 8.75 | 16.39 | 1.87 | 590 6190.98 | 65 11.02 | 2.37 (1.85–3.02) | 11 325 |
| Stem cell | 133.45 | 303.81 | 2.28 | 16.67 | 29.26 | 1.75 | 325 3296.15 | 70 21.54 | 2.42 (1.94–2.98) | 9860 |
| Diagnosis . | Average Cost of Visit (in $1000) . | Average Length of Stay (Days) . | Infection, No., Rate per 100 000 . | Deaths, No., % Infected . | Relative Risk of Mortality (95% CI) . | Population, No. . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| – . | + . | Ratio . | – . | + . | Ratio . | |||||
| All visits with at-risk diagnoses | 30.43 | 101.02 | 3.41 | 5.53 | 13.40 | 2.59 | 12 030 67.53 | 1240 10.31 | 3.19 (3.03–3.36) | 17 813 520 |
| Cancer | 77.68 | 307.23 | 3.96 | 6.00 | 17.96 | 2.99 | 3190 114.56 | 715 22.41 | 2.91 (2.72–3.11) | 2 784 530 |
| Leukemia | 108.71 | 373.40 | 3.43 | 8.06 | 22.34 | 2.77 | 2205 823.08 | 285 12.93 | 2.46 (2.21–2.74) | 267 895 |
| Lung, trachea, bronchus | 69.18 | 146.82 | 2.12 | 6.00 | 9.86 | 1.64 | 670 169.77 | 110 16.42 | 1.90 (1.60–2.25) | 394 645 |
| Non-Hodgkin lymphoma | 89.38 | 364.86 | 4.08 | 6.54 | 18.87 | 2.89 | 555 278.80 | 115 20.72 | 4.43 (3.75–5.20) | 199 065 |
| Cystic fibrosis | 51.40 | 69.38 | 1.35 | 9.39 | 12.11 | 1.29 | 1800 5939.61 | 20 1.11 | 1.05 (.67–1.63) | 282 645 |
| Influenza | 55.59 | 275.87 | 4.96 | 5.43 | 17.18 | 3.16 | 575 152.14 | 85 14.78 | 4.23 (3.46–5.13) | 377 950 |
| Transplant history | 35.42 | 113.04 | 3.19 | 5.41 | 14.56 | 2.69 | 1170 444.65 | 135 11.54 | 4.82 (4.10–5.63) | 282 645 |
| Bone marrow | 48.39 | 72.19 | 1.49 | 6.83 | 11.97 | 1.75 | 170 781.25 | 40 23.53 | 5.80 (4.35–7.57) | 1005 |
| Kidney | 29.06 | 120.19 | 4.14 | 4.90 | 12.95 | 2.64 | 190 159.80 | 20 10.53 | 5.54 (3.63–8.27) | 118 895 |
| Lung | 36.82 | 63.47 | 1.72 | 5.94 | 14.56 | 2.69 | 205 1851.02 | a | 1.06 (.45–2.44) | 11 075 |
| Stem cell | 54.29 | 153.34 | 2.83 | 6.85 | 17.64 | 2.57 | 390 1015.76 | 60 15.38 | 3.49 (2.74–4.40) | 38 395 |
| Transplant complications | 68.62 | 206.00 | 3.00 | 8.39 | 21.91 | 2.61 | 1350 1046.07 | 205 15.19 | 4.34 (3.81–4.94) | 142 875 |
| Bone marrow | 98.91 | 321.76 | 3.25 | 11.88 | 36.85 | 3.10 | 65 2260.87 | a | 2.76 (1.51–4.77) | 2900 |
| Kidney | 47.33 | 119.94 | 2.53 | 7.01 | 16.11 | 2.30 | 225 285.88 | 40 17.78 | 6.97 (5.21–9.17) | 85 650 |
| Lung | 112.28 | 144.78 | 1.72 | 8.75 | 16.39 | 1.87 | 590 6190.98 | 65 11.02 | 2.37 (1.85–3.02) | 11 325 |
| Stem cell | 133.45 | 303.81 | 2.28 | 16.67 | 29.26 | 1.75 | 325 3296.15 | 70 21.54 | 2.42 (1.94–2.98) | 9860 |
Abbreviation: CI, confidence interval.
Estimates suppressed with Healthcare Cost and Utilization Project protocols.
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