Table III Open in new tab Top 20 genes...

Gene symbol

Gene full name

Degree layout

P-value

Fold change

Il6

Interleukin-6

138

5.00E−05

4.651158164

Vegfa

Vascular endothelial growth factor A

5.00E−05

6.178428794

Hgf

Hepatocyte growth factor

5.00E−05

0.138921327

Il1b

Interleukin-1β

5.00E−05

0.133212374

P4hb

Prolyl 4-hydroxylase, β subunit

5.00E−05

2.088344901

Thbs1

Thrombospondin-1

5.00E−05

0.116907549

Cd34

Cluster of differentiation 34

0.02555

0.228519629

Hspa5

Hsp70 member 5

5.00E−05

2.58429363

Ncam1

Neural cell adhesion molecule 1

0.00395

3.875224792

Irs1

Insulin receptor substrate 1

0.0032

0.193315604

Cxcl12

C-X-C Motif Chemokine Ligand 12

0.0025

0.495140547

Met

MET Proto-Oncogene

5.00E−05

0.112293786

Pdgfrb

Platelet-derived growth factor receptor-β

5.00E−05

0.104211038

Pik3r1

Phosphoinositide-3-Kinase Regulatory Subunit 1

5.00E−05

0.371622562

Acly

ATP citrate lyase

5.00E−05

2.174117631

Itgb3

integrin beta 3

5.00E−05

5.155312921

Igf1r

insulin-like growth factor 1 receptor

5.00E−05

2.008655289

Csf1

Colony Stimulating Factor 1

5.00E−05

0.160547266

Nrp1

Neuropilin 1

5.00E−05

0.232224163

Itga2b

Integrin Subunit Alpha 2b

0.0098

0.355044066

Runx2

RUNX Family Transcription Factor 2

5.00E−05

5.950248826

Table III

Open in new tab

Top 20 genes with a protein–protein interaction degree of >40.

Gene symbol	Gene full name	Degree layout	P-value	Fold change
Il6	Interleukin-6	138	5.00E−05	4.651158164
Vegfa	Vascular endothelial growth factor A	96	5.00E−05	6.178428794
Hgf	Hepatocyte growth factor	57	5.00E−05	0.138921327
Il1b	Interleukin-1β	57	5.00E−05	0.133212374
P4hb	Prolyl 4-hydroxylase, β subunit	54	5.00E−05	2.088344901
Thbs1	Thrombospondin-1	54	5.00E−05	0.116907549
Cd34	Cluster of differentiation 34	51	0.02555	0.228519629
Hspa5	Hsp70 member 5	50	5.00E−05	2.58429363
Ncam1	Neural cell adhesion molecule 1	49	0.00395	3.875224792
Irs1	Insulin receptor substrate 1	46	0.0032	0.193315604
Cxcl12	C-X-C Motif Chemokine Ligand 12	46	0.0025	0.495140547
Met	MET Proto-Oncogene	45	5.00E−05	0.112293786
Pdgfrb	Platelet-derived growth factor receptor-β	45	5.00E−05	0.104211038
Pik3r1	Phosphoinositide-3-Kinase Regulatory Subunit 1	45	5.00E−05	0.371622562
Acly	ATP citrate lyase	45	5.00E−05	2.174117631
Itgb3	integrin beta 3	44	5.00E−05	5.155312921
Igf1r	insulin-like growth factor 1 receptor	43	5.00E−05	2.008655289
Csf1	Colony Stimulating Factor 1	43	5.00E−05	0.160547266
Nrp1	Neuropilin 1	42	5.00E−05	0.232224163
Itga2b	Integrin Subunit Alpha 2b	41	0.0098	0.355044066
Runx2	RUNX Family Transcription Factor 2	41	5.00E−05	5.950248826

Gene symbol	Gene full name	Degree layout	P-value	Fold change
Il6	Interleukin-6	138	5.00E−05	4.651158164
Vegfa	Vascular endothelial growth factor A	96	5.00E−05	6.178428794
Hgf	Hepatocyte growth factor	57	5.00E−05	0.138921327
Il1b	Interleukin-1β	57	5.00E−05	0.133212374
P4hb	Prolyl 4-hydroxylase, β subunit	54	5.00E−05	2.088344901
Thbs1	Thrombospondin-1	54	5.00E−05	0.116907549
Cd34	Cluster of differentiation 34	51	0.02555	0.228519629
Hspa5	Hsp70 member 5	50	5.00E−05	2.58429363
Ncam1	Neural cell adhesion molecule 1	49	0.00395	3.875224792
Irs1	Insulin receptor substrate 1	46	0.0032	0.193315604
Cxcl12	C-X-C Motif Chemokine Ligand 12	46	0.0025	0.495140547
Met	MET Proto-Oncogene	45	5.00E−05	0.112293786
Pdgfrb	Platelet-derived growth factor receptor-β	45	5.00E−05	0.104211038
Pik3r1	Phosphoinositide-3-Kinase Regulatory Subunit 1	45	5.00E−05	0.371622562
Acly	ATP citrate lyase	45	5.00E−05	2.174117631
Itgb3	integrin beta 3	44	5.00E−05	5.155312921
Igf1r	insulin-like growth factor 1 receptor	43	5.00E−05	2.008655289
Csf1	Colony Stimulating Factor 1	43	5.00E−05	0.160547266
Nrp1	Neuropilin 1	42	5.00E−05	0.232224163
Itga2b	Integrin Subunit Alpha 2b	41	0.0098	0.355044066
Runx2	RUNX Family Transcription Factor 2	41	5.00E−05	5.950248826

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