Intraoperative characteristics and unadjusted postoperative patient outcomes
| Outcome . | Group 1 . | Group 2 . | P-values . |
|---|---|---|---|
| Cross-clamp time (min) | 68 | 69 | 0.09 |
| CPB time (min) | 89 | 91 | 0.07 |
| CPB priming volume (ml) | 1000 | 1600 | 0.03 |
| IAD volume (ml) | 655 | 390 | 0.02 |
| Chest tube output (ml) | 350 | 730 | 0.01 |
| Respiratory failure | 34 (3%) | 263 (7%) | 0.03 |
| Pneumonia | 11 (1%) | 116 (3.1%) | 0.01 |
| Stroke | 14 (1.2%) | 49 (1.3%) | 0.89 |
| Perioperative myocardial infarction | 1 (0.1%) | 4 (0.1%) | 0.99 |
| Renal failure | 33 (2.9%) | 101 (2.7%) | 0.1 |
| Reoperated for bleeding | 14 (1.2%) | 94 (2.5%) | 0.04 |
| Length of stay (days) | 6.1 | 8.2 | 0.05 |
| 30-day mortality | 10 (0.9%) | 64 (1.7%) | 0.02 |
| Intraoperative transfusions | |||
| Total PRBCs | 326 (29%) | 1841 (49%) | 0.02 |
| PRBCs (units)a | 0.2 ± 0.9 | 0.7 ± 1.4 | 0.02 |
| FFP (units) | 0.1 ± 0.2 | 0.1 ± 0.3 | 0.2 |
| Platelets (units) | 0.2 ± 0.9 | 0.3 ± 1.1 | 0.06 |
| Cryoprecipitate (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.8 |
| Postoperative transfusionsb | |||
| Total PRBCs | 203 (18%) | 1090 (29%) | 0.01 |
| PRBCs (units) | 0.1 ± 0.7 | 0.6 ± 1.1 | 0.02 |
| FFP (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.2 |
| Platelets (units) | 0.1 ± 0.7 | 0.2 ± 1.0 | 0.06 |
| Cryoprecipitate (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.8 |
| Haematocrita | |||
| End of operation (%) | 32 ± 3 | 33 ± 3 | 0.2 |
| At discharge (%) | 31 ± 2 | 32 ± 2 | 0.2 |
| Outcome . | Group 1 . | Group 2 . | P-values . |
|---|---|---|---|
| Cross-clamp time (min) | 68 | 69 | 0.09 |
| CPB time (min) | 89 | 91 | 0.07 |
| CPB priming volume (ml) | 1000 | 1600 | 0.03 |
| IAD volume (ml) | 655 | 390 | 0.02 |
| Chest tube output (ml) | 350 | 730 | 0.01 |
| Respiratory failure | 34 (3%) | 263 (7%) | 0.03 |
| Pneumonia | 11 (1%) | 116 (3.1%) | 0.01 |
| Stroke | 14 (1.2%) | 49 (1.3%) | 0.89 |
| Perioperative myocardial infarction | 1 (0.1%) | 4 (0.1%) | 0.99 |
| Renal failure | 33 (2.9%) | 101 (2.7%) | 0.1 |
| Reoperated for bleeding | 14 (1.2%) | 94 (2.5%) | 0.04 |
| Length of stay (days) | 6.1 | 8.2 | 0.05 |
| 30-day mortality | 10 (0.9%) | 64 (1.7%) | 0.02 |
| Intraoperative transfusions | |||
| Total PRBCs | 326 (29%) | 1841 (49%) | 0.02 |
| PRBCs (units)a | 0.2 ± 0.9 | 0.7 ± 1.4 | 0.02 |
| FFP (units) | 0.1 ± 0.2 | 0.1 ± 0.3 | 0.2 |
| Platelets (units) | 0.2 ± 0.9 | 0.3 ± 1.1 | 0.06 |
| Cryoprecipitate (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.8 |
| Postoperative transfusionsb | |||
| Total PRBCs | 203 (18%) | 1090 (29%) | 0.01 |
| PRBCs (units) | 0.1 ± 0.7 | 0.6 ± 1.1 | 0.02 |
| FFP (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.2 |
| Platelets (units) | 0.1 ± 0.7 | 0.2 ± 1.0 | 0.06 |
| Cryoprecipitate (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.8 |
| Haematocrita | |||
| End of operation (%) | 32 ± 3 | 33 ± 3 | 0.2 |
| At discharge (%) | 31 ± 2 | 32 ± 2 | 0.2 |
aResults reported as mean ± standard deviation.
bPostoperative period is 30 days.
CPB: cardiopulmonary bypass; IAD: intraoperative autologous donation; PRBCs: packed red-blood cells; MI: myocardial infarction; FFP: fresh frozen plasma.
Intraoperative characteristics and unadjusted postoperative patient outcomes
| Outcome . | Group 1 . | Group 2 . | P-values . |
|---|---|---|---|
| Cross-clamp time (min) | 68 | 69 | 0.09 |
| CPB time (min) | 89 | 91 | 0.07 |
| CPB priming volume (ml) | 1000 | 1600 | 0.03 |
| IAD volume (ml) | 655 | 390 | 0.02 |
| Chest tube output (ml) | 350 | 730 | 0.01 |
| Respiratory failure | 34 (3%) | 263 (7%) | 0.03 |
| Pneumonia | 11 (1%) | 116 (3.1%) | 0.01 |
| Stroke | 14 (1.2%) | 49 (1.3%) | 0.89 |
| Perioperative myocardial infarction | 1 (0.1%) | 4 (0.1%) | 0.99 |
| Renal failure | 33 (2.9%) | 101 (2.7%) | 0.1 |
| Reoperated for bleeding | 14 (1.2%) | 94 (2.5%) | 0.04 |
| Length of stay (days) | 6.1 | 8.2 | 0.05 |
| 30-day mortality | 10 (0.9%) | 64 (1.7%) | 0.02 |
| Intraoperative transfusions | |||
| Total PRBCs | 326 (29%) | 1841 (49%) | 0.02 |
| PRBCs (units)a | 0.2 ± 0.9 | 0.7 ± 1.4 | 0.02 |
| FFP (units) | 0.1 ± 0.2 | 0.1 ± 0.3 | 0.2 |
| Platelets (units) | 0.2 ± 0.9 | 0.3 ± 1.1 | 0.06 |
| Cryoprecipitate (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.8 |
| Postoperative transfusionsb | |||
| Total PRBCs | 203 (18%) | 1090 (29%) | 0.01 |
| PRBCs (units) | 0.1 ± 0.7 | 0.6 ± 1.1 | 0.02 |
| FFP (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.2 |
| Platelets (units) | 0.1 ± 0.7 | 0.2 ± 1.0 | 0.06 |
| Cryoprecipitate (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.8 |
| Haematocrita | |||
| End of operation (%) | 32 ± 3 | 33 ± 3 | 0.2 |
| At discharge (%) | 31 ± 2 | 32 ± 2 | 0.2 |
| Outcome . | Group 1 . | Group 2 . | P-values . |
|---|---|---|---|
| Cross-clamp time (min) | 68 | 69 | 0.09 |
| CPB time (min) | 89 | 91 | 0.07 |
| CPB priming volume (ml) | 1000 | 1600 | 0.03 |
| IAD volume (ml) | 655 | 390 | 0.02 |
| Chest tube output (ml) | 350 | 730 | 0.01 |
| Respiratory failure | 34 (3%) | 263 (7%) | 0.03 |
| Pneumonia | 11 (1%) | 116 (3.1%) | 0.01 |
| Stroke | 14 (1.2%) | 49 (1.3%) | 0.89 |
| Perioperative myocardial infarction | 1 (0.1%) | 4 (0.1%) | 0.99 |
| Renal failure | 33 (2.9%) | 101 (2.7%) | 0.1 |
| Reoperated for bleeding | 14 (1.2%) | 94 (2.5%) | 0.04 |
| Length of stay (days) | 6.1 | 8.2 | 0.05 |
| 30-day mortality | 10 (0.9%) | 64 (1.7%) | 0.02 |
| Intraoperative transfusions | |||
| Total PRBCs | 326 (29%) | 1841 (49%) | 0.02 |
| PRBCs (units)a | 0.2 ± 0.9 | 0.7 ± 1.4 | 0.02 |
| FFP (units) | 0.1 ± 0.2 | 0.1 ± 0.3 | 0.2 |
| Platelets (units) | 0.2 ± 0.9 | 0.3 ± 1.1 | 0.06 |
| Cryoprecipitate (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.8 |
| Postoperative transfusionsb | |||
| Total PRBCs | 203 (18%) | 1090 (29%) | 0.01 |
| PRBCs (units) | 0.1 ± 0.7 | 0.6 ± 1.1 | 0.02 |
| FFP (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.2 |
| Platelets (units) | 0.1 ± 0.7 | 0.2 ± 1.0 | 0.06 |
| Cryoprecipitate (units) | 0.1 ± 0.1 | 0.1 ± 0.2 | 0.8 |
| Haematocrita | |||
| End of operation (%) | 32 ± 3 | 33 ± 3 | 0.2 |
| At discharge (%) | 31 ± 2 | 32 ± 2 | 0.2 |
aResults reported as mean ± standard deviation.
bPostoperative period is 30 days.
CPB: cardiopulmonary bypass; IAD: intraoperative autologous donation; PRBCs: packed red-blood cells; MI: myocardial infarction; FFP: fresh frozen plasma.
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