Clinical outcomes of ICSI cycles using the spermatozoa from the patients carried AKAP4 variant
| Subject . | F1a: II-1b . | F2a: II-1b . | F3a: II-1b . |
|---|---|---|---|
| Male age (year) | 32 | 29 | 37 |
| Female age (year) | 28 | 31 | 35 |
| Number of ICSI cycles | 1 | 1 | 1 |
| Number of oocytes injected | 9 | 6 | 4 |
| Number (and rate) of fertilized oocytes | 9(100%) | 6(100%) | 3(75%) |
| Number (and rate) of cleavage embryos | 9(100%) | 6(100%) | 3(100%) |
| Number (and rate) of 8-cells | 9(100%) | 6(100%) | 2(67%) |
| Number (and rate) of blastocysts | 9(100%) | 5(83%) | 2(67%) |
| Number of transfer cycles | 1 | 1 | 1 |
| Number of embryos transferred per cycle | 2 | 2 | 2 |
| Implantation rate | 50% | 50% | 0 |
| Clinical pregnancy rate | 100% | 100% | 0% |
| Miscarriage rate | NAc | NAc | NAc |
| Subject . | F1a: II-1b . | F2a: II-1b . | F3a: II-1b . |
|---|---|---|---|
| Male age (year) | 32 | 29 | 37 |
| Female age (year) | 28 | 31 | 35 |
| Number of ICSI cycles | 1 | 1 | 1 |
| Number of oocytes injected | 9 | 6 | 4 |
| Number (and rate) of fertilized oocytes | 9(100%) | 6(100%) | 3(75%) |
| Number (and rate) of cleavage embryos | 9(100%) | 6(100%) | 3(100%) |
| Number (and rate) of 8-cells | 9(100%) | 6(100%) | 2(67%) |
| Number (and rate) of blastocysts | 9(100%) | 5(83%) | 2(67%) |
| Number of transfer cycles | 1 | 1 | 1 |
| Number of embryos transferred per cycle | 2 | 2 | 2 |
| Implantation rate | 50% | 50% | 0 |
| Clinical pregnancy rate | 100% | 100% | 0% |
| Miscarriage rate | NAc | NAc | NAc |
aF1–F3 represent family 1–3.
bII-1 represent the patient number.
c‘NA’ represent unclear.
Clinical outcomes of ICSI cycles using the spermatozoa from the patients carried AKAP4 variant
| Subject . | F1a: II-1b . | F2a: II-1b . | F3a: II-1b . |
|---|---|---|---|
| Male age (year) | 32 | 29 | 37 |
| Female age (year) | 28 | 31 | 35 |
| Number of ICSI cycles | 1 | 1 | 1 |
| Number of oocytes injected | 9 | 6 | 4 |
| Number (and rate) of fertilized oocytes | 9(100%) | 6(100%) | 3(75%) |
| Number (and rate) of cleavage embryos | 9(100%) | 6(100%) | 3(100%) |
| Number (and rate) of 8-cells | 9(100%) | 6(100%) | 2(67%) |
| Number (and rate) of blastocysts | 9(100%) | 5(83%) | 2(67%) |
| Number of transfer cycles | 1 | 1 | 1 |
| Number of embryos transferred per cycle | 2 | 2 | 2 |
| Implantation rate | 50% | 50% | 0 |
| Clinical pregnancy rate | 100% | 100% | 0% |
| Miscarriage rate | NAc | NAc | NAc |
| Subject . | F1a: II-1b . | F2a: II-1b . | F3a: II-1b . |
|---|---|---|---|
| Male age (year) | 32 | 29 | 37 |
| Female age (year) | 28 | 31 | 35 |
| Number of ICSI cycles | 1 | 1 | 1 |
| Number of oocytes injected | 9 | 6 | 4 |
| Number (and rate) of fertilized oocytes | 9(100%) | 6(100%) | 3(75%) |
| Number (and rate) of cleavage embryos | 9(100%) | 6(100%) | 3(100%) |
| Number (and rate) of 8-cells | 9(100%) | 6(100%) | 2(67%) |
| Number (and rate) of blastocysts | 9(100%) | 5(83%) | 2(67%) |
| Number of transfer cycles | 1 | 1 | 1 |
| Number of embryos transferred per cycle | 2 | 2 | 2 |
| Implantation rate | 50% | 50% | 0 |
| Clinical pregnancy rate | 100% | 100% | 0% |
| Miscarriage rate | NAc | NAc | NAc |
aF1–F3 represent family 1–3.
bII-1 represent the patient number.
c‘NA’ represent unclear.
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