Table 2

Suggested surgical management of breast cancer during pregnancy based on trimester at presentation

TrimesterSurgical management
First

1.  Chemotherapy not appropriate

 

2.  Consider awaiting the second trimester to initiate therapy depending on disease severity and week of gestation

 

3.  Consider surgery cautiously with RSI and FM

Second

1.  Consider neoadjuvant chemotherapy to downstage disease and allow for further workup

 

2.  Consider surgery (using RSI and FM) followed by adjuvant chemotherapy

Third

1.  Chemotherapy not appropriate unless it can be halted approximately 3–4 wk before EDD; can resume after delivery or proceed with surgery after delivery

 

2.  Consider surgery cautiously (using RSI, FM, and proper positioning) followed by adjuvant therapy after delivery

 

3.  Consider awaiting or hastening delivery and treating in the postpartum period depending on disease severity and week of gestation/fetal maturity

TrimesterSurgical management
First

1.  Chemotherapy not appropriate

 

2.  Consider awaiting the second trimester to initiate therapy depending on disease severity and week of gestation

 

3.  Consider surgery cautiously with RSI and FM

Second

1.  Consider neoadjuvant chemotherapy to downstage disease and allow for further workup

 

2.  Consider surgery (using RSI and FM) followed by adjuvant chemotherapy

Third

1.  Chemotherapy not appropriate unless it can be halted approximately 3–4 wk before EDD; can resume after delivery or proceed with surgery after delivery

 

2.  Consider surgery cautiously (using RSI, FM, and proper positioning) followed by adjuvant therapy after delivery

 

3.  Consider awaiting or hastening delivery and treating in the postpartum period depending on disease severity and week of gestation/fetal maturity

Abbreviations: EDD, estimated due date; FM, fetal monitoring; RSI, rapid sequence induction.

Table 2

Suggested surgical management of breast cancer during pregnancy based on trimester at presentation

TrimesterSurgical management
First

1.  Chemotherapy not appropriate

 

2.  Consider awaiting the second trimester to initiate therapy depending on disease severity and week of gestation

 

3.  Consider surgery cautiously with RSI and FM

Second

1.  Consider neoadjuvant chemotherapy to downstage disease and allow for further workup

 

2.  Consider surgery (using RSI and FM) followed by adjuvant chemotherapy

Third

1.  Chemotherapy not appropriate unless it can be halted approximately 3–4 wk before EDD; can resume after delivery or proceed with surgery after delivery

 

2.  Consider surgery cautiously (using RSI, FM, and proper positioning) followed by adjuvant therapy after delivery

 

3.  Consider awaiting or hastening delivery and treating in the postpartum period depending on disease severity and week of gestation/fetal maturity

TrimesterSurgical management
First

1.  Chemotherapy not appropriate

 

2.  Consider awaiting the second trimester to initiate therapy depending on disease severity and week of gestation

 

3.  Consider surgery cautiously with RSI and FM

Second

1.  Consider neoadjuvant chemotherapy to downstage disease and allow for further workup

 

2.  Consider surgery (using RSI and FM) followed by adjuvant chemotherapy

Third

1.  Chemotherapy not appropriate unless it can be halted approximately 3–4 wk before EDD; can resume after delivery or proceed with surgery after delivery

 

2.  Consider surgery cautiously (using RSI, FM, and proper positioning) followed by adjuvant therapy after delivery

 

3.  Consider awaiting or hastening delivery and treating in the postpartum period depending on disease severity and week of gestation/fetal maturity

Abbreviations: EDD, estimated due date; FM, fetal monitoring; RSI, rapid sequence induction.

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