Table 1

Historical comparison of the efficacy and tolerability of third-generation regimens

aOnly the study of Scagliotti et al. [7] reported alopecia among toxicities; however, alopecia is a common side effect of docetaxel, with an incidence in the range of 60%–75%, depending on whether the drug is used as monotherapy or in combination with cisplatin.

Abbreviations: CBDCA, carboplatin; CDDP, cisplatin; Gem, gemcitabine; MS, median survival; NA, not applicable; PTX, paclitaxel; RR, response rate; TXT, docetaxel; VNB, vinorelbine.

Table 1

Historical comparison of the efficacy and tolerability of third-generation regimens

aOnly the study of Scagliotti et al. [7] reported alopecia among toxicities; however, alopecia is a common side effect of docetaxel, with an incidence in the range of 60%–75%, depending on whether the drug is used as monotherapy or in combination with cisplatin.

Abbreviations: CBDCA, carboplatin; CDDP, cisplatin; Gem, gemcitabine; MS, median survival; NA, not applicable; PTX, paclitaxel; RR, response rate; TXT, docetaxel; VNB, vinorelbine.

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