| . | Hypo-HT Group (n = 98) . | Eu-HT Group (n = 69) . | P-value . |
|---|---|---|---|
| Age, median (range) | 33 (19–44) | 32.5 (23-43) | ns |
| Parity | ns | ||
| Nulliparous, n (%) | 42 (42.9) | 32 (46.4) | |
| ≥1 pregnancy, n (%) | 56 (57.1) | 37 (53.6) | |
| History of miscarriage, n (%) | 22 (22.4) | 20 (28.9) | ns |
| Smoking habit | ns | ||
| Never, n (%) | 80 (81.6) | 57 (82.6) | |
| Former smoker, n (%) | 15 (15.3) | 11 (15.9) | |
| Current smoker, n (%) | 3 (3.1) | 1 (1.44) | |
| Regular use of iodized salt, n (%) | 57 (58.2) | 35 (50.7) | ns |
| Years of iodized salt use, M ± SD (range) | 8.0 ± 7.8 (1–34) | 6.5 ± 5.3 (1-20) | ns |
| Use of I containing supplements, n (%) | 62 (63.3) | 56 (81.1) | 0.012 |
| I intake by supplements (μg/day), M ± SD (range) | 190.6 ± 33.9 (75–300) | 184.5 ± 26.4 (150-225) | ns |
| Use of Se containing supplements, n (%) | 41 (41.8) | 31 (44.9) | ns |
| Se intake by supplements (μg/day), M ± SD (range) | 40.9 ± 12.6 (30–55) | 38.9 ± 12.2 (30-55) | ns |
| 1st-trim TPOAb positivity, n (%) | 75 (76.5) | 57 (82.6) | ns |
| 1st-trim TPOAb values (IU/mL), M ± SD (range) | 314.1 ± 405 (42.9–2222) | 303.9 ± 446.7 (48.7-2292) | ns |
| Postpartum TPOAb positivity, n (%) | 86 (87.5) | 65 (95.2) | ns |
| Postpartum TPOAB values (IU/mL), M ± SD (range) | 364.7 ± 496.6 (34.6–3054) | 404.4 ± 611.4 (41.1-3138) | ns |
| Preconception TSH (mU/L), M ± SD (range) | 1.05 ± 0.74 (0.10–3.01) | 1.53 ± 0.71 (0.51-3.29) | <0.0001 |
| Timing of preconception TSH sampling (weeks), M ± SD | 15.4 ± 4.9 | 14.5 ± 4.8 | ns |
| Preconception LT4 doses (mcg/kg/d), M ± SD | 1.52 ± 0.44 | NA | — |
| . | Hypo-HT Group (n = 98) . | Eu-HT Group (n = 69) . | P-value . |
|---|---|---|---|
| Age, median (range) | 33 (19–44) | 32.5 (23-43) | ns |
| Parity | ns | ||
| Nulliparous, n (%) | 42 (42.9) | 32 (46.4) | |
| ≥1 pregnancy, n (%) | 56 (57.1) | 37 (53.6) | |
| History of miscarriage, n (%) | 22 (22.4) | 20 (28.9) | ns |
| Smoking habit | ns | ||
| Never, n (%) | 80 (81.6) | 57 (82.6) | |
| Former smoker, n (%) | 15 (15.3) | 11 (15.9) | |
| Current smoker, n (%) | 3 (3.1) | 1 (1.44) | |
| Regular use of iodized salt, n (%) | 57 (58.2) | 35 (50.7) | ns |
| Years of iodized salt use, M ± SD (range) | 8.0 ± 7.8 (1–34) | 6.5 ± 5.3 (1-20) | ns |
| Use of I containing supplements, n (%) | 62 (63.3) | 56 (81.1) | 0.012 |
| I intake by supplements (μg/day), M ± SD (range) | 190.6 ± 33.9 (75–300) | 184.5 ± 26.4 (150-225) | ns |
| Use of Se containing supplements, n (%) | 41 (41.8) | 31 (44.9) | ns |
| Se intake by supplements (μg/day), M ± SD (range) | 40.9 ± 12.6 (30–55) | 38.9 ± 12.2 (30-55) | ns |
| 1st-trim TPOAb positivity, n (%) | 75 (76.5) | 57 (82.6) | ns |
| 1st-trim TPOAb values (IU/mL), M ± SD (range) | 314.1 ± 405 (42.9–2222) | 303.9 ± 446.7 (48.7-2292) | ns |
| Postpartum TPOAb positivity, n (%) | 86 (87.5) | 65 (95.2) | ns |
| Postpartum TPOAB values (IU/mL), M ± SD (range) | 364.7 ± 496.6 (34.6–3054) | 404.4 ± 611.4 (41.1-3138) | ns |
| Preconception TSH (mU/L), M ± SD (range) | 1.05 ± 0.74 (0.10–3.01) | 1.53 ± 0.71 (0.51-3.29) | <0.0001 |
| Timing of preconception TSH sampling (weeks), M ± SD | 15.4 ± 4.9 | 14.5 ± 4.8 | ns |
| Preconception LT4 doses (mcg/kg/d), M ± SD | 1.52 ± 0.44 | NA | — |
Abbreviations: NA, not applicable. ns, not significant; SD, standard deviation; trim, trimester.
| . | Hypo-HT Group (n = 98) . | Eu-HT Group (n = 69) . | P-value . |
|---|---|---|---|
| Age, median (range) | 33 (19–44) | 32.5 (23-43) | ns |
| Parity | ns | ||
| Nulliparous, n (%) | 42 (42.9) | 32 (46.4) | |
| ≥1 pregnancy, n (%) | 56 (57.1) | 37 (53.6) | |
| History of miscarriage, n (%) | 22 (22.4) | 20 (28.9) | ns |
| Smoking habit | ns | ||
| Never, n (%) | 80 (81.6) | 57 (82.6) | |
| Former smoker, n (%) | 15 (15.3) | 11 (15.9) | |
| Current smoker, n (%) | 3 (3.1) | 1 (1.44) | |
| Regular use of iodized salt, n (%) | 57 (58.2) | 35 (50.7) | ns |
| Years of iodized salt use, M ± SD (range) | 8.0 ± 7.8 (1–34) | 6.5 ± 5.3 (1-20) | ns |
| Use of I containing supplements, n (%) | 62 (63.3) | 56 (81.1) | 0.012 |
| I intake by supplements (μg/day), M ± SD (range) | 190.6 ± 33.9 (75–300) | 184.5 ± 26.4 (150-225) | ns |
| Use of Se containing supplements, n (%) | 41 (41.8) | 31 (44.9) | ns |
| Se intake by supplements (μg/day), M ± SD (range) | 40.9 ± 12.6 (30–55) | 38.9 ± 12.2 (30-55) | ns |
| 1st-trim TPOAb positivity, n (%) | 75 (76.5) | 57 (82.6) | ns |
| 1st-trim TPOAb values (IU/mL), M ± SD (range) | 314.1 ± 405 (42.9–2222) | 303.9 ± 446.7 (48.7-2292) | ns |
| Postpartum TPOAb positivity, n (%) | 86 (87.5) | 65 (95.2) | ns |
| Postpartum TPOAB values (IU/mL), M ± SD (range) | 364.7 ± 496.6 (34.6–3054) | 404.4 ± 611.4 (41.1-3138) | ns |
| Preconception TSH (mU/L), M ± SD (range) | 1.05 ± 0.74 (0.10–3.01) | 1.53 ± 0.71 (0.51-3.29) | <0.0001 |
| Timing of preconception TSH sampling (weeks), M ± SD | 15.4 ± 4.9 | 14.5 ± 4.8 | ns |
| Preconception LT4 doses (mcg/kg/d), M ± SD | 1.52 ± 0.44 | NA | — |
| . | Hypo-HT Group (n = 98) . | Eu-HT Group (n = 69) . | P-value . |
|---|---|---|---|
| Age, median (range) | 33 (19–44) | 32.5 (23-43) | ns |
| Parity | ns | ||
| Nulliparous, n (%) | 42 (42.9) | 32 (46.4) | |
| ≥1 pregnancy, n (%) | 56 (57.1) | 37 (53.6) | |
| History of miscarriage, n (%) | 22 (22.4) | 20 (28.9) | ns |
| Smoking habit | ns | ||
| Never, n (%) | 80 (81.6) | 57 (82.6) | |
| Former smoker, n (%) | 15 (15.3) | 11 (15.9) | |
| Current smoker, n (%) | 3 (3.1) | 1 (1.44) | |
| Regular use of iodized salt, n (%) | 57 (58.2) | 35 (50.7) | ns |
| Years of iodized salt use, M ± SD (range) | 8.0 ± 7.8 (1–34) | 6.5 ± 5.3 (1-20) | ns |
| Use of I containing supplements, n (%) | 62 (63.3) | 56 (81.1) | 0.012 |
| I intake by supplements (μg/day), M ± SD (range) | 190.6 ± 33.9 (75–300) | 184.5 ± 26.4 (150-225) | ns |
| Use of Se containing supplements, n (%) | 41 (41.8) | 31 (44.9) | ns |
| Se intake by supplements (μg/day), M ± SD (range) | 40.9 ± 12.6 (30–55) | 38.9 ± 12.2 (30-55) | ns |
| 1st-trim TPOAb positivity, n (%) | 75 (76.5) | 57 (82.6) | ns |
| 1st-trim TPOAb values (IU/mL), M ± SD (range) | 314.1 ± 405 (42.9–2222) | 303.9 ± 446.7 (48.7-2292) | ns |
| Postpartum TPOAb positivity, n (%) | 86 (87.5) | 65 (95.2) | ns |
| Postpartum TPOAB values (IU/mL), M ± SD (range) | 364.7 ± 496.6 (34.6–3054) | 404.4 ± 611.4 (41.1-3138) | ns |
| Preconception TSH (mU/L), M ± SD (range) | 1.05 ± 0.74 (0.10–3.01) | 1.53 ± 0.71 (0.51-3.29) | <0.0001 |
| Timing of preconception TSH sampling (weeks), M ± SD | 15.4 ± 4.9 | 14.5 ± 4.8 | ns |
| Preconception LT4 doses (mcg/kg/d), M ± SD | 1.52 ± 0.44 | NA | — |
Abbreviations: NA, not applicable. ns, not significant; SD, standard deviation; trim, trimester.
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