Summary of hematologic and nonhematologic toxicities associated with the combination of vinorelbine plus trastuzumab (n = 313 courses)
| . | Events, n (%) . | |||
|---|---|---|---|---|
| . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . |
| Hematologic toxicity | ||||
| Neutropenia | 21 (7) | 94 (30) | 64 (20) | 44 (14) |
| Anemia | 175 (56) | 52 (17) | 1 (<1) | 0 |
| Nonhematologic toxicity | ||||
| Alopecia | 20 (6) | 1 (<1) | 0 | 0 |
| Vomiting | 7 (2) | 2 (1) | 0 | 0 |
| Stomatitis | 1 (<1) | 2 (1) | 0 | 0 |
| Neuropathy | 54 (17) | 5 (2) | 3 (1) | 0 |
| Nausea | 31 (10) | 4 (1) | 0 | 0 |
| Constipation | 26 (8) | 3 (1) | 1 (<1) | 0 |
| Cardiotoxicity | 0 | 3 (1) | 0 | 0 |
| Infusion-site reaction | 6 (2) | 0 | 1 (<1) | 0 |
| Phlebitis | 0 | 3 (1) | 0 | 0 |
| . | Events, n (%) . | |||
|---|---|---|---|---|
| . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . |
| Hematologic toxicity | ||||
| Neutropenia | 21 (7) | 94 (30) | 64 (20) | 44 (14) |
| Anemia | 175 (56) | 52 (17) | 1 (<1) | 0 |
| Nonhematologic toxicity | ||||
| Alopecia | 20 (6) | 1 (<1) | 0 | 0 |
| Vomiting | 7 (2) | 2 (1) | 0 | 0 |
| Stomatitis | 1 (<1) | 2 (1) | 0 | 0 |
| Neuropathy | 54 (17) | 5 (2) | 3 (1) | 0 |
| Nausea | 31 (10) | 4 (1) | 0 | 0 |
| Constipation | 26 (8) | 3 (1) | 1 (<1) | 0 |
| Cardiotoxicity | 0 | 3 (1) | 0 | 0 |
| Infusion-site reaction | 6 (2) | 0 | 1 (<1) | 0 |
| Phlebitis | 0 | 3 (1) | 0 | 0 |
Summary of hematologic and nonhematologic toxicities associated with the combination of vinorelbine plus trastuzumab (n = 313 courses)
| . | Events, n (%) . | |||
|---|---|---|---|---|
| . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . |
| Hematologic toxicity | ||||
| Neutropenia | 21 (7) | 94 (30) | 64 (20) | 44 (14) |
| Anemia | 175 (56) | 52 (17) | 1 (<1) | 0 |
| Nonhematologic toxicity | ||||
| Alopecia | 20 (6) | 1 (<1) | 0 | 0 |
| Vomiting | 7 (2) | 2 (1) | 0 | 0 |
| Stomatitis | 1 (<1) | 2 (1) | 0 | 0 |
| Neuropathy | 54 (17) | 5 (2) | 3 (1) | 0 |
| Nausea | 31 (10) | 4 (1) | 0 | 0 |
| Constipation | 26 (8) | 3 (1) | 1 (<1) | 0 |
| Cardiotoxicity | 0 | 3 (1) | 0 | 0 |
| Infusion-site reaction | 6 (2) | 0 | 1 (<1) | 0 |
| Phlebitis | 0 | 3 (1) | 0 | 0 |
| . | Events, n (%) . | |||
|---|---|---|---|---|
| . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . |
| Hematologic toxicity | ||||
| Neutropenia | 21 (7) | 94 (30) | 64 (20) | 44 (14) |
| Anemia | 175 (56) | 52 (17) | 1 (<1) | 0 |
| Nonhematologic toxicity | ||||
| Alopecia | 20 (6) | 1 (<1) | 0 | 0 |
| Vomiting | 7 (2) | 2 (1) | 0 | 0 |
| Stomatitis | 1 (<1) | 2 (1) | 0 | 0 |
| Neuropathy | 54 (17) | 5 (2) | 3 (1) | 0 |
| Nausea | 31 (10) | 4 (1) | 0 | 0 |
| Constipation | 26 (8) | 3 (1) | 1 (<1) | 0 |
| Cardiotoxicity | 0 | 3 (1) | 0 | 0 |
| Infusion-site reaction | 6 (2) | 0 | 1 (<1) | 0 |
| Phlebitis | 0 | 3 (1) | 0 | 0 |
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
