Prescribed drugs and dialysis treatment characteristics for incident peritoneal patients between 2006 and 2015
Time period . | 2006–2007 . | 2008–2009 . | 2010–2011 . | 2012–2013 . | 2014–2015 . | P-valuea . |
---|---|---|---|---|---|---|
N | 647 | 660 | 604 | 610 | 601 | |
Dialysis treatment characteristics | ||||||
Dialysis vintage (months), mean (SD) | 6.9 (3.4) | 5.9 (3.4) | 6.1 (3.3) | 5.9 (3.5) | 6.1 (3.5) | 0.01 |
Proportion of APD, % | 15 | 19 | 24 | 23 | 24 | <0.001 |
Kt/V/week, mean (SD) (n = 1517) | 2.3 (0.6) | 2.4 (0.8) | 2.3 (0.6) | 2.4 (0.6) | 2.2 (0.6) | 0.08 |
CCr/week, mean (SD) (n = 1476) | 82 (28.0) | 79 (27.8) | 83 (32.6) | 83 (32.8) | 81 (27.9) | 0.81 |
Proportion icodextrin, % | 26 | 33 | 31 | 37 | 40 | <0.001 |
Proportion APD + icodextrin, % | 7.4 | 8.2 | 9.3 | 11.0 | 12.6 | <0.001 |
Assisted PD, % | 1.4 | 4.2 | 10.4 | 10.7 | 11.8 | <0.001 |
Medications, % | ||||||
ACEis/ARBs | 69 | 71 | 69 | 63 | 61 | <0.001 |
Beta-blockers | 75 | 73 | 77 | 74 | 77 | 0.35 |
Calcium channel blockers | 73 | 76 | 75 | 77 | 83 | 0.01 |
Other antihypertensive drugs | 23 | 26 | 30 | 31 | 41 | <0.001 |
Diuretics | 89 | 90 | 87 | 88 | 86 | 0.07 |
Statins | 59 | 57 | 57 | 61 | 56 | 0.67 |
Erythropoietin/darbepoetin | 86 | 88 | 82 | 80 | 83 | 0.001 |
Iron (oral/intravenous) | 58 | 60 | 57 | 45 | 46 | <0.001 |
Phosphate binders (non-calcium based) | 57 | 65 | 67 | 71 | 76 | <0.001 |
Calcium supplementsb | 68 | 68 | 61 | 53 | 52 | <0.001 |
Vitamin D3 supplements | 78 | 83 | 81 | 82 | 81 | 0.24 |
Cinacalcet | 4 | 7 | 7 | 9 | 8 | 0.01 |
Time period . | 2006–2007 . | 2008–2009 . | 2010–2011 . | 2012–2013 . | 2014–2015 . | P-valuea . |
---|---|---|---|---|---|---|
N | 647 | 660 | 604 | 610 | 601 | |
Dialysis treatment characteristics | ||||||
Dialysis vintage (months), mean (SD) | 6.9 (3.4) | 5.9 (3.4) | 6.1 (3.3) | 5.9 (3.5) | 6.1 (3.5) | 0.01 |
Proportion of APD, % | 15 | 19 | 24 | 23 | 24 | <0.001 |
Kt/V/week, mean (SD) (n = 1517) | 2.3 (0.6) | 2.4 (0.8) | 2.3 (0.6) | 2.4 (0.6) | 2.2 (0.6) | 0.08 |
CCr/week, mean (SD) (n = 1476) | 82 (28.0) | 79 (27.8) | 83 (32.6) | 83 (32.8) | 81 (27.9) | 0.81 |
Proportion icodextrin, % | 26 | 33 | 31 | 37 | 40 | <0.001 |
Proportion APD + icodextrin, % | 7.4 | 8.2 | 9.3 | 11.0 | 12.6 | <0.001 |
Assisted PD, % | 1.4 | 4.2 | 10.4 | 10.7 | 11.8 | <0.001 |
Medications, % | ||||||
ACEis/ARBs | 69 | 71 | 69 | 63 | 61 | <0.001 |
Beta-blockers | 75 | 73 | 77 | 74 | 77 | 0.35 |
Calcium channel blockers | 73 | 76 | 75 | 77 | 83 | 0.01 |
Other antihypertensive drugs | 23 | 26 | 30 | 31 | 41 | <0.001 |
Diuretics | 89 | 90 | 87 | 88 | 86 | 0.07 |
Statins | 59 | 57 | 57 | 61 | 56 | 0.67 |
Erythropoietin/darbepoetin | 86 | 88 | 82 | 80 | 83 | 0.001 |
Iron (oral/intravenous) | 58 | 60 | 57 | 45 | 46 | <0.001 |
Phosphate binders (non-calcium based) | 57 | 65 | 67 | 71 | 76 | <0.001 |
Calcium supplementsb | 68 | 68 | 61 | 53 | 52 | <0.001 |
Vitamin D3 supplements | 78 | 83 | 81 | 82 | 81 | 0.24 |
Cinacalcet | 4 | 7 | 7 | 9 | 8 | 0.01 |
aP-values were tested with a Jonckheere–Terpstra trend test for categorical variables and with a linear-by-linear trend test for continuous data. Significant values are in bold.
bCalcium supplements include calcium-containing phosphate binders.
Prescribed drugs and dialysis treatment characteristics for incident peritoneal patients between 2006 and 2015
Time period . | 2006–2007 . | 2008–2009 . | 2010–2011 . | 2012–2013 . | 2014–2015 . | P-valuea . |
---|---|---|---|---|---|---|
N | 647 | 660 | 604 | 610 | 601 | |
Dialysis treatment characteristics | ||||||
Dialysis vintage (months), mean (SD) | 6.9 (3.4) | 5.9 (3.4) | 6.1 (3.3) | 5.9 (3.5) | 6.1 (3.5) | 0.01 |
Proportion of APD, % | 15 | 19 | 24 | 23 | 24 | <0.001 |
Kt/V/week, mean (SD) (n = 1517) | 2.3 (0.6) | 2.4 (0.8) | 2.3 (0.6) | 2.4 (0.6) | 2.2 (0.6) | 0.08 |
CCr/week, mean (SD) (n = 1476) | 82 (28.0) | 79 (27.8) | 83 (32.6) | 83 (32.8) | 81 (27.9) | 0.81 |
Proportion icodextrin, % | 26 | 33 | 31 | 37 | 40 | <0.001 |
Proportion APD + icodextrin, % | 7.4 | 8.2 | 9.3 | 11.0 | 12.6 | <0.001 |
Assisted PD, % | 1.4 | 4.2 | 10.4 | 10.7 | 11.8 | <0.001 |
Medications, % | ||||||
ACEis/ARBs | 69 | 71 | 69 | 63 | 61 | <0.001 |
Beta-blockers | 75 | 73 | 77 | 74 | 77 | 0.35 |
Calcium channel blockers | 73 | 76 | 75 | 77 | 83 | 0.01 |
Other antihypertensive drugs | 23 | 26 | 30 | 31 | 41 | <0.001 |
Diuretics | 89 | 90 | 87 | 88 | 86 | 0.07 |
Statins | 59 | 57 | 57 | 61 | 56 | 0.67 |
Erythropoietin/darbepoetin | 86 | 88 | 82 | 80 | 83 | 0.001 |
Iron (oral/intravenous) | 58 | 60 | 57 | 45 | 46 | <0.001 |
Phosphate binders (non-calcium based) | 57 | 65 | 67 | 71 | 76 | <0.001 |
Calcium supplementsb | 68 | 68 | 61 | 53 | 52 | <0.001 |
Vitamin D3 supplements | 78 | 83 | 81 | 82 | 81 | 0.24 |
Cinacalcet | 4 | 7 | 7 | 9 | 8 | 0.01 |
Time period . | 2006–2007 . | 2008–2009 . | 2010–2011 . | 2012–2013 . | 2014–2015 . | P-valuea . |
---|---|---|---|---|---|---|
N | 647 | 660 | 604 | 610 | 601 | |
Dialysis treatment characteristics | ||||||
Dialysis vintage (months), mean (SD) | 6.9 (3.4) | 5.9 (3.4) | 6.1 (3.3) | 5.9 (3.5) | 6.1 (3.5) | 0.01 |
Proportion of APD, % | 15 | 19 | 24 | 23 | 24 | <0.001 |
Kt/V/week, mean (SD) (n = 1517) | 2.3 (0.6) | 2.4 (0.8) | 2.3 (0.6) | 2.4 (0.6) | 2.2 (0.6) | 0.08 |
CCr/week, mean (SD) (n = 1476) | 82 (28.0) | 79 (27.8) | 83 (32.6) | 83 (32.8) | 81 (27.9) | 0.81 |
Proportion icodextrin, % | 26 | 33 | 31 | 37 | 40 | <0.001 |
Proportion APD + icodextrin, % | 7.4 | 8.2 | 9.3 | 11.0 | 12.6 | <0.001 |
Assisted PD, % | 1.4 | 4.2 | 10.4 | 10.7 | 11.8 | <0.001 |
Medications, % | ||||||
ACEis/ARBs | 69 | 71 | 69 | 63 | 61 | <0.001 |
Beta-blockers | 75 | 73 | 77 | 74 | 77 | 0.35 |
Calcium channel blockers | 73 | 76 | 75 | 77 | 83 | 0.01 |
Other antihypertensive drugs | 23 | 26 | 30 | 31 | 41 | <0.001 |
Diuretics | 89 | 90 | 87 | 88 | 86 | 0.07 |
Statins | 59 | 57 | 57 | 61 | 56 | 0.67 |
Erythropoietin/darbepoetin | 86 | 88 | 82 | 80 | 83 | 0.001 |
Iron (oral/intravenous) | 58 | 60 | 57 | 45 | 46 | <0.001 |
Phosphate binders (non-calcium based) | 57 | 65 | 67 | 71 | 76 | <0.001 |
Calcium supplementsb | 68 | 68 | 61 | 53 | 52 | <0.001 |
Vitamin D3 supplements | 78 | 83 | 81 | 82 | 81 | 0.24 |
Cinacalcet | 4 | 7 | 7 | 9 | 8 | 0.01 |
aP-values were tested with a Jonckheere–Terpstra trend test for categorical variables and with a linear-by-linear trend test for continuous data. Significant values are in bold.
bCalcium supplements include calcium-containing phosphate binders.
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