Variable . | Surgically treated (n = 32) . | Medically-treated (n = 10) . | P . |
---|---|---|---|
Age (years) | 50 ± 8 | 59 ± 11 | 0.01 |
Female Sex (n, % F) | 18 (57%) | 5 (50%) | 0.34 |
BMI (Kg/m2) | 24.5 ± 4.5 | 25.0 ± 5.0 | 0.63 |
BSA (m2) | 1.83 ± 0.23 | 1.84 ± 0.25 | 0.62 |
Systolic BP (mmHg) | 155 ± 18 | 149 ± 7 | 0.13 |
Diastolic BP (mmHg) | 93 ± 13 | 88 ± 11 | 0.26 |
Serum Creatinine (micromol/L) | 74 ± 16 | 64 ± 5.6 | 0.04 |
Serum Na + (mmol/L) | 143 ± 2 | 142 ± 2 | 0.34 |
Serum K + (mmol/L) | 3.3 ± 0.6 | 3.6 ± 0.4 | 0.15 |
Urinary Na + Excretion (mmol/day) | 152 ± 62 | 161 ± 43 | 0.68 |
Urinary K + Excretion (mmol/day) | 81 ± 35 | 88 ± 26 | 0.56 |
DRC (mIU/L) | 2.0 (2.0-2.0) | 2.3 (2.0–3.8) | 0.20 |
PAC (ng/dL) | 24.6 (16.2–29.9) | 15.5 (13.1–18.8) | 0.01 |
ARR (ng/mIU) | 95.8 (67.0–136.7) | 63.6 (34.5–94.2) | 0.04 |
Variable . | Surgically treated (n = 32) . | Medically-treated (n = 10) . | P . |
---|---|---|---|
Age (years) | 50 ± 8 | 59 ± 11 | 0.01 |
Female Sex (n, % F) | 18 (57%) | 5 (50%) | 0.34 |
BMI (Kg/m2) | 24.5 ± 4.5 | 25.0 ± 5.0 | 0.63 |
BSA (m2) | 1.83 ± 0.23 | 1.84 ± 0.25 | 0.62 |
Systolic BP (mmHg) | 155 ± 18 | 149 ± 7 | 0.13 |
Diastolic BP (mmHg) | 93 ± 13 | 88 ± 11 | 0.26 |
Serum Creatinine (micromol/L) | 74 ± 16 | 64 ± 5.6 | 0.04 |
Serum Na + (mmol/L) | 143 ± 2 | 142 ± 2 | 0.34 |
Serum K + (mmol/L) | 3.3 ± 0.6 | 3.6 ± 0.4 | 0.15 |
Urinary Na + Excretion (mmol/day) | 152 ± 62 | 161 ± 43 | 0.68 |
Urinary K + Excretion (mmol/day) | 81 ± 35 | 88 ± 26 | 0.56 |
DRC (mIU/L) | 2.0 (2.0-2.0) | 2.3 (2.0–3.8) | 0.20 |
PAC (ng/dL) | 24.6 (16.2–29.9) | 15.5 (13.1–18.8) | 0.01 |
ARR (ng/mIU) | 95.8 (67.0–136.7) | 63.6 (34.5–94.2) | 0.04 |
For ARR calculation, the minimum value of DRC was set at 2.0 mIU/L. Normal values on a 100–200 mmol Na+/day: DRC > 2.8 mIU/L, PAC < 12 ng/dL, ARR < 20.6 (ng/mIU). Data are presented as mean ± SD or median and interquartile range, as appropriate.
Abbreviations: ARR, aldosterone/renin ratio; BP, blood pressure; BMI, body mass Index; BSA, body surface area; DRC, direct active renin concentration; PAC, plasma aldosterone concentration.
Variable . | Surgically treated (n = 32) . | Medically-treated (n = 10) . | P . |
---|---|---|---|
Age (years) | 50 ± 8 | 59 ± 11 | 0.01 |
Female Sex (n, % F) | 18 (57%) | 5 (50%) | 0.34 |
BMI (Kg/m2) | 24.5 ± 4.5 | 25.0 ± 5.0 | 0.63 |
BSA (m2) | 1.83 ± 0.23 | 1.84 ± 0.25 | 0.62 |
Systolic BP (mmHg) | 155 ± 18 | 149 ± 7 | 0.13 |
Diastolic BP (mmHg) | 93 ± 13 | 88 ± 11 | 0.26 |
Serum Creatinine (micromol/L) | 74 ± 16 | 64 ± 5.6 | 0.04 |
Serum Na + (mmol/L) | 143 ± 2 | 142 ± 2 | 0.34 |
Serum K + (mmol/L) | 3.3 ± 0.6 | 3.6 ± 0.4 | 0.15 |
Urinary Na + Excretion (mmol/day) | 152 ± 62 | 161 ± 43 | 0.68 |
Urinary K + Excretion (mmol/day) | 81 ± 35 | 88 ± 26 | 0.56 |
DRC (mIU/L) | 2.0 (2.0-2.0) | 2.3 (2.0–3.8) | 0.20 |
PAC (ng/dL) | 24.6 (16.2–29.9) | 15.5 (13.1–18.8) | 0.01 |
ARR (ng/mIU) | 95.8 (67.0–136.7) | 63.6 (34.5–94.2) | 0.04 |
Variable . | Surgically treated (n = 32) . | Medically-treated (n = 10) . | P . |
---|---|---|---|
Age (years) | 50 ± 8 | 59 ± 11 | 0.01 |
Female Sex (n, % F) | 18 (57%) | 5 (50%) | 0.34 |
BMI (Kg/m2) | 24.5 ± 4.5 | 25.0 ± 5.0 | 0.63 |
BSA (m2) | 1.83 ± 0.23 | 1.84 ± 0.25 | 0.62 |
Systolic BP (mmHg) | 155 ± 18 | 149 ± 7 | 0.13 |
Diastolic BP (mmHg) | 93 ± 13 | 88 ± 11 | 0.26 |
Serum Creatinine (micromol/L) | 74 ± 16 | 64 ± 5.6 | 0.04 |
Serum Na + (mmol/L) | 143 ± 2 | 142 ± 2 | 0.34 |
Serum K + (mmol/L) | 3.3 ± 0.6 | 3.6 ± 0.4 | 0.15 |
Urinary Na + Excretion (mmol/day) | 152 ± 62 | 161 ± 43 | 0.68 |
Urinary K + Excretion (mmol/day) | 81 ± 35 | 88 ± 26 | 0.56 |
DRC (mIU/L) | 2.0 (2.0-2.0) | 2.3 (2.0–3.8) | 0.20 |
PAC (ng/dL) | 24.6 (16.2–29.9) | 15.5 (13.1–18.8) | 0.01 |
ARR (ng/mIU) | 95.8 (67.0–136.7) | 63.6 (34.5–94.2) | 0.04 |
For ARR calculation, the minimum value of DRC was set at 2.0 mIU/L. Normal values on a 100–200 mmol Na+/day: DRC > 2.8 mIU/L, PAC < 12 ng/dL, ARR < 20.6 (ng/mIU). Data are presented as mean ± SD or median and interquartile range, as appropriate.
Abbreviations: ARR, aldosterone/renin ratio; BP, blood pressure; BMI, body mass Index; BSA, body surface area; DRC, direct active renin concentration; PAC, plasma aldosterone concentration.
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