Table 1.

Demographic and Clinical Features at Baseline of the PA Patients

VariableSurgically treated (n = 32)Medically-treated (n = 10)P
Age (years)50 ± 859 ± 110.01
Female Sex (n, % F)18 (57%)5 (50%)0.34
BMI (Kg/m2)24.5 ± 4.525.0 ± 5.00.63
BSA (m2)1.83 ± 0.231.84 ± 0.250.62
Systolic BP (mmHg)155 ± 18149 ± 70.13
Diastolic BP (mmHg)93 ± 1388 ± 110.26
Serum Creatinine (micromol/L) 74 ± 1664 ± 5.60.04
Serum Na  + (mmol/L)143 ± 2142 ± 20.34
Serum K  + (mmol/L)3.3 ± 0.63.6 ± 0.40.15
Urinary Na  +  Excretion (mmol/day)152 ± 62161 ± 430.68
Urinary K  +  Excretion (mmol/day)81 ± 3588 ± 260.56
DRC (mIU/L)2.0 (2.0-2.0)2.3 (2.0–3.8)0.20
PAC (ng/dL)24.6 (16.2–29.9) 15.5 (13.1–18.8)0.01
ARR (ng/mIU)95.8 (67.0–136.7)63.6 (34.5–94.2)0.04
VariableSurgically treated (n = 32)Medically-treated (n = 10)P
Age (years)50 ± 859 ± 110.01
Female Sex (n, % F)18 (57%)5 (50%)0.34
BMI (Kg/m2)24.5 ± 4.525.0 ± 5.00.63
BSA (m2)1.83 ± 0.231.84 ± 0.250.62
Systolic BP (mmHg)155 ± 18149 ± 70.13
Diastolic BP (mmHg)93 ± 1388 ± 110.26
Serum Creatinine (micromol/L) 74 ± 1664 ± 5.60.04
Serum Na  + (mmol/L)143 ± 2142 ± 20.34
Serum K  + (mmol/L)3.3 ± 0.63.6 ± 0.40.15
Urinary Na  +  Excretion (mmol/day)152 ± 62161 ± 430.68
Urinary K  +  Excretion (mmol/day)81 ± 3588 ± 260.56
DRC (mIU/L)2.0 (2.0-2.0)2.3 (2.0–3.8)0.20
PAC (ng/dL)24.6 (16.2–29.9) 15.5 (13.1–18.8)0.01
ARR (ng/mIU)95.8 (67.0–136.7)63.6 (34.5–94.2)0.04

For ARR calculation, the minimum value of DRC was set at 2.0 mIU/L. Normal values on a 100–200 mmol Na+/day: DRC > 2.8 mIU/L, PAC < 12 ng/dL, ARR < 20.6 (ng/mIU). Data are presented as mean ± SD or median and interquartile range, as appropriate.

Abbreviations: ARR, aldosterone/renin ratio; BP, blood pressure; BMI, body mass Index; BSA, body surface area; DRC, direct active renin concentration; PAC, plasma aldosterone concentration.

Table 1.

Demographic and Clinical Features at Baseline of the PA Patients

VariableSurgically treated (n = 32)Medically-treated (n = 10)P
Age (years)50 ± 859 ± 110.01
Female Sex (n, % F)18 (57%)5 (50%)0.34
BMI (Kg/m2)24.5 ± 4.525.0 ± 5.00.63
BSA (m2)1.83 ± 0.231.84 ± 0.250.62
Systolic BP (mmHg)155 ± 18149 ± 70.13
Diastolic BP (mmHg)93 ± 1388 ± 110.26
Serum Creatinine (micromol/L) 74 ± 1664 ± 5.60.04
Serum Na  + (mmol/L)143 ± 2142 ± 20.34
Serum K  + (mmol/L)3.3 ± 0.63.6 ± 0.40.15
Urinary Na  +  Excretion (mmol/day)152 ± 62161 ± 430.68
Urinary K  +  Excretion (mmol/day)81 ± 3588 ± 260.56
DRC (mIU/L)2.0 (2.0-2.0)2.3 (2.0–3.8)0.20
PAC (ng/dL)24.6 (16.2–29.9) 15.5 (13.1–18.8)0.01
ARR (ng/mIU)95.8 (67.0–136.7)63.6 (34.5–94.2)0.04
VariableSurgically treated (n = 32)Medically-treated (n = 10)P
Age (years)50 ± 859 ± 110.01
Female Sex (n, % F)18 (57%)5 (50%)0.34
BMI (Kg/m2)24.5 ± 4.525.0 ± 5.00.63
BSA (m2)1.83 ± 0.231.84 ± 0.250.62
Systolic BP (mmHg)155 ± 18149 ± 70.13
Diastolic BP (mmHg)93 ± 1388 ± 110.26
Serum Creatinine (micromol/L) 74 ± 1664 ± 5.60.04
Serum Na  + (mmol/L)143 ± 2142 ± 20.34
Serum K  + (mmol/L)3.3 ± 0.63.6 ± 0.40.15
Urinary Na  +  Excretion (mmol/day)152 ± 62161 ± 430.68
Urinary K  +  Excretion (mmol/day)81 ± 3588 ± 260.56
DRC (mIU/L)2.0 (2.0-2.0)2.3 (2.0–3.8)0.20
PAC (ng/dL)24.6 (16.2–29.9) 15.5 (13.1–18.8)0.01
ARR (ng/mIU)95.8 (67.0–136.7)63.6 (34.5–94.2)0.04

For ARR calculation, the minimum value of DRC was set at 2.0 mIU/L. Normal values on a 100–200 mmol Na+/day: DRC > 2.8 mIU/L, PAC < 12 ng/dL, ARR < 20.6 (ng/mIU). Data are presented as mean ± SD or median and interquartile range, as appropriate.

Abbreviations: ARR, aldosterone/renin ratio; BP, blood pressure; BMI, body mass Index; BSA, body surface area; DRC, direct active renin concentration; PAC, plasma aldosterone concentration.

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