Comparison of Baseline SBA Titers, and Levels of Cytokines and Host Defense Peptides Between Adults and Children
| Variables . | Adults . | Children . | P Value . |
|---|---|---|---|
| SBA | 57.7 (55.3–118.1) | 32 (16–32) | .003 |
| IL-7 | 11.1 (9.2–12.4) | 23.2 (16.3–35.2) | <.001 |
| IL-17 | 155.6 (104–240) | 111 (87.4–143.8) | .003 |
| TNF-α | 509.4 (311–997) | 212.4 (157–286) | <.001 |
| MIP-1β | 222 (105–663) | 65.8 (29.0–167) | <.001 |
| G-CSF | 2494 (1344–7656) | 590 (334–1908) | .001 |
| IL-10 | 28.2 (23.1–42.2) | 29.4 (16.9–42.9) | .437 |
| IL-13 | 5.82 (4.68–9.1) | 4.7 (3.0–7.0) | .053 |
| GM-CSF | 355 (295–381) | 54.7 (20.0–102) | <.001 |
| LL-37 | 3.08 (2.50–3.56) | 2.38 (1.81–2.95) | .003 |
| HBD-1 | 509 (467–631) | 337 (297–395) | <.001 |
| Variables . | Adults . | Children . | P Value . |
|---|---|---|---|
| SBA | 57.7 (55.3–118.1) | 32 (16–32) | .003 |
| IL-7 | 11.1 (9.2–12.4) | 23.2 (16.3–35.2) | <.001 |
| IL-17 | 155.6 (104–240) | 111 (87.4–143.8) | .003 |
| TNF-α | 509.4 (311–997) | 212.4 (157–286) | <.001 |
| MIP-1β | 222 (105–663) | 65.8 (29.0–167) | <.001 |
| G-CSF | 2494 (1344–7656) | 590 (334–1908) | .001 |
| IL-10 | 28.2 (23.1–42.2) | 29.4 (16.9–42.9) | .437 |
| IL-13 | 5.82 (4.68–9.1) | 4.7 (3.0–7.0) | .053 |
| GM-CSF | 355 (295–381) | 54.7 (20.0–102) | <.001 |
| LL-37 | 3.08 (2.50–3.56) | 2.38 (1.81–2.95) | .003 |
| HBD-1 | 509 (467–631) | 337 (297–395) | <.001 |
Data are median (interquartile range). Statistical significance was determined using Mann-Whitney U test for unequal samples.
Abbreviations: G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; HBD-1, human β defensin-1; IL, interleukin; MIP-1β, macrophage inflammatory protein-1β; SBA, serum bactericidal antibody; TNF-α, tumor necrosis factor-α.
Comparison of Baseline SBA Titers, and Levels of Cytokines and Host Defense Peptides Between Adults and Children
| Variables . | Adults . | Children . | P Value . |
|---|---|---|---|
| SBA | 57.7 (55.3–118.1) | 32 (16–32) | .003 |
| IL-7 | 11.1 (9.2–12.4) | 23.2 (16.3–35.2) | <.001 |
| IL-17 | 155.6 (104–240) | 111 (87.4–143.8) | .003 |
| TNF-α | 509.4 (311–997) | 212.4 (157–286) | <.001 |
| MIP-1β | 222 (105–663) | 65.8 (29.0–167) | <.001 |
| G-CSF | 2494 (1344–7656) | 590 (334–1908) | .001 |
| IL-10 | 28.2 (23.1–42.2) | 29.4 (16.9–42.9) | .437 |
| IL-13 | 5.82 (4.68–9.1) | 4.7 (3.0–7.0) | .053 |
| GM-CSF | 355 (295–381) | 54.7 (20.0–102) | <.001 |
| LL-37 | 3.08 (2.50–3.56) | 2.38 (1.81–2.95) | .003 |
| HBD-1 | 509 (467–631) | 337 (297–395) | <.001 |
| Variables . | Adults . | Children . | P Value . |
|---|---|---|---|
| SBA | 57.7 (55.3–118.1) | 32 (16–32) | .003 |
| IL-7 | 11.1 (9.2–12.4) | 23.2 (16.3–35.2) | <.001 |
| IL-17 | 155.6 (104–240) | 111 (87.4–143.8) | .003 |
| TNF-α | 509.4 (311–997) | 212.4 (157–286) | <.001 |
| MIP-1β | 222 (105–663) | 65.8 (29.0–167) | <.001 |
| G-CSF | 2494 (1344–7656) | 590 (334–1908) | .001 |
| IL-10 | 28.2 (23.1–42.2) | 29.4 (16.9–42.9) | .437 |
| IL-13 | 5.82 (4.68–9.1) | 4.7 (3.0–7.0) | .053 |
| GM-CSF | 355 (295–381) | 54.7 (20.0–102) | <.001 |
| LL-37 | 3.08 (2.50–3.56) | 2.38 (1.81–2.95) | .003 |
| HBD-1 | 509 (467–631) | 337 (297–395) | <.001 |
Data are median (interquartile range). Statistical significance was determined using Mann-Whitney U test for unequal samples.
Abbreviations: G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; HBD-1, human β defensin-1; IL, interleukin; MIP-1β, macrophage inflammatory protein-1β; SBA, serum bactericidal antibody; TNF-α, tumor necrosis factor-α.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
