| Test . | Sensitivity . | Specificity . | Other details . |
|---|---|---|---|
| TUBEX® TF69–71 | 78% (95% CI 71–85%) | 87% (95% CI 82–91%) | Colorimetric assay—detects IgM directed against Salmonella Typhi O9 lipopolysaccharide antigen |
| Test-It Typhoid69–71 | 69% (95% CI 59–78%) | 90% (95% CI 78–93%) | Lateral flow assay IgM antibodies against S. Typhi O antigen |
| Typhidot69–71 | 84% (95% CI 73–91%) | 79% (95% CI 70–87%). | Detects specific IgM and IgG antibodies against the 50 kDa bacterial outer membrane protein (OMP) |
| TPtesta68 | 96.0% (95% CI: 87.1–99.8%) | 96.6% (95% CI: 90.7–99.2%) | Utilizes circulating IgA antibodies against the bacteria using ELISA |
| Widal test72 | 73.5 (95% CI: 60.9–86.1%) | 75.7% (Range: 13.8–98%) | Detects IgM and IgG antibodies, against O (surface polysaccharide) antigen and H (flagellar) antigen |
| Test . | Sensitivity . | Specificity . | Other details . |
|---|---|---|---|
| TUBEX® TF69–71 | 78% (95% CI 71–85%) | 87% (95% CI 82–91%) | Colorimetric assay—detects IgM directed against Salmonella Typhi O9 lipopolysaccharide antigen |
| Test-It Typhoid69–71 | 69% (95% CI 59–78%) | 90% (95% CI 78–93%) | Lateral flow assay IgM antibodies against S. Typhi O antigen |
| Typhidot69–71 | 84% (95% CI 73–91%) | 79% (95% CI 70–87%). | Detects specific IgM and IgG antibodies against the 50 kDa bacterial outer membrane protein (OMP) |
| TPtesta68 | 96.0% (95% CI: 87.1–99.8%) | 96.6% (95% CI: 90.7–99.2%) | Utilizes circulating IgA antibodies against the bacteria using ELISA |
| Widal test72 | 73.5 (95% CI: 60.9–86.1%) | 75.7% (Range: 13.8–98%) | Detects IgM and IgG antibodies, against O (surface polysaccharide) antigen and H (flagellar) antigen |
The table compares the performance of common serological tests for the diagnosis of enteric fever from endemic areas
aEvaluated only in a small number of studies
| Test . | Sensitivity . | Specificity . | Other details . |
|---|---|---|---|
| TUBEX® TF69–71 | 78% (95% CI 71–85%) | 87% (95% CI 82–91%) | Colorimetric assay—detects IgM directed against Salmonella Typhi O9 lipopolysaccharide antigen |
| Test-It Typhoid69–71 | 69% (95% CI 59–78%) | 90% (95% CI 78–93%) | Lateral flow assay IgM antibodies against S. Typhi O antigen |
| Typhidot69–71 | 84% (95% CI 73–91%) | 79% (95% CI 70–87%). | Detects specific IgM and IgG antibodies against the 50 kDa bacterial outer membrane protein (OMP) |
| TPtesta68 | 96.0% (95% CI: 87.1–99.8%) | 96.6% (95% CI: 90.7–99.2%) | Utilizes circulating IgA antibodies against the bacteria using ELISA |
| Widal test72 | 73.5 (95% CI: 60.9–86.1%) | 75.7% (Range: 13.8–98%) | Detects IgM and IgG antibodies, against O (surface polysaccharide) antigen and H (flagellar) antigen |
| Test . | Sensitivity . | Specificity . | Other details . |
|---|---|---|---|
| TUBEX® TF69–71 | 78% (95% CI 71–85%) | 87% (95% CI 82–91%) | Colorimetric assay—detects IgM directed against Salmonella Typhi O9 lipopolysaccharide antigen |
| Test-It Typhoid69–71 | 69% (95% CI 59–78%) | 90% (95% CI 78–93%) | Lateral flow assay IgM antibodies against S. Typhi O antigen |
| Typhidot69–71 | 84% (95% CI 73–91%) | 79% (95% CI 70–87%). | Detects specific IgM and IgG antibodies against the 50 kDa bacterial outer membrane protein (OMP) |
| TPtesta68 | 96.0% (95% CI: 87.1–99.8%) | 96.6% (95% CI: 90.7–99.2%) | Utilizes circulating IgA antibodies against the bacteria using ELISA |
| Widal test72 | 73.5 (95% CI: 60.9–86.1%) | 75.7% (Range: 13.8–98%) | Detects IgM and IgG antibodies, against O (surface polysaccharide) antigen and H (flagellar) antigen |
The table compares the performance of common serological tests for the diagnosis of enteric fever from endemic areas
aEvaluated only in a small number of studies
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