Blood gas analysis of arterial blood in offspring rats after different treatments
| Group . | AB (mM) . | SB (mM) . | BE(ecf) (mM) . | BE(B) (mM) . | tCO2 (mM) . |
|---|---|---|---|---|---|
| Saline | 22.83±4.82 | 17.55±3.62 | −4.32±0.63 | −6.73±0.62 | 22.33±5.41 |
| Vitamin B6 | 23.25±5.43 | 15.64±4.89 | −4.58±0.75 | −6.46±0.84 | 23.54±4.66 |
| Fingolimod | 22.55±4.67 | 16.84±6.86 | −4.74±0.54 | −6.92±0.26 | 38.33±6.46# |
| Isocarbophos | 24.61±6.56 | 18.12±5.73 | −4.12±0.58 | −6.33±0.56 | 39.53±6.12# |
| Isocarbophos+Vitamin B6 | 21.22±6.25 | 17.65±3.74 | −4.91±0.66 | −5.92±0.74 | 29.13±5.35* |
| Isocarbophos+Vitamin B6+Fingolimod | 22.34±5.63 | 16.73±4.66 | −4.82±0.69 | −6.61±0.76 | 37.86±6.92& |
| Group . | AB (mM) . | SB (mM) . | BE(ecf) (mM) . | BE(B) (mM) . | tCO2 (mM) . |
|---|---|---|---|---|---|
| Saline | 22.83±4.82 | 17.55±3.62 | −4.32±0.63 | −6.73±0.62 | 22.33±5.41 |
| Vitamin B6 | 23.25±5.43 | 15.64±4.89 | −4.58±0.75 | −6.46±0.84 | 23.54±4.66 |
| Fingolimod | 22.55±4.67 | 16.84±6.86 | −4.74±0.54 | −6.92±0.26 | 38.33±6.46# |
| Isocarbophos | 24.61±6.56 | 18.12±5.73 | −4.12±0.58 | −6.33±0.56 | 39.53±6.12# |
| Isocarbophos+Vitamin B6 | 21.22±6.25 | 17.65±3.74 | −4.91±0.66 | −5.92±0.74 | 29.13±5.35* |
| Isocarbophos+Vitamin B6+Fingolimod | 22.34±5.63 | 16.73±4.66 | −4.82±0.69 | −6.61±0.76 | 37.86±6.92& |
After Isocarbophos treatment, arterial blood of offspring rats was collected from left ventricles for blood gas analysis. AB: actual bicarbonate; SB: standard bicarbonate; [BE(ecf)]: base excess extracellular fluid; [BE(B)]: base excess of blood; tCO2: total carbon dioxide. Data are expressed as the mean±SD, n = 8.
P<0.05 vs Saline group.
P<0.05 vs Isocarbophos group.
P<0.05 vs Isocarbophos+Vitamin B6.
Blood gas analysis of arterial blood in offspring rats after different treatments
| Group . | AB (mM) . | SB (mM) . | BE(ecf) (mM) . | BE(B) (mM) . | tCO2 (mM) . |
|---|---|---|---|---|---|
| Saline | 22.83±4.82 | 17.55±3.62 | −4.32±0.63 | −6.73±0.62 | 22.33±5.41 |
| Vitamin B6 | 23.25±5.43 | 15.64±4.89 | −4.58±0.75 | −6.46±0.84 | 23.54±4.66 |
| Fingolimod | 22.55±4.67 | 16.84±6.86 | −4.74±0.54 | −6.92±0.26 | 38.33±6.46# |
| Isocarbophos | 24.61±6.56 | 18.12±5.73 | −4.12±0.58 | −6.33±0.56 | 39.53±6.12# |
| Isocarbophos+Vitamin B6 | 21.22±6.25 | 17.65±3.74 | −4.91±0.66 | −5.92±0.74 | 29.13±5.35* |
| Isocarbophos+Vitamin B6+Fingolimod | 22.34±5.63 | 16.73±4.66 | −4.82±0.69 | −6.61±0.76 | 37.86±6.92& |
| Group . | AB (mM) . | SB (mM) . | BE(ecf) (mM) . | BE(B) (mM) . | tCO2 (mM) . |
|---|---|---|---|---|---|
| Saline | 22.83±4.82 | 17.55±3.62 | −4.32±0.63 | −6.73±0.62 | 22.33±5.41 |
| Vitamin B6 | 23.25±5.43 | 15.64±4.89 | −4.58±0.75 | −6.46±0.84 | 23.54±4.66 |
| Fingolimod | 22.55±4.67 | 16.84±6.86 | −4.74±0.54 | −6.92±0.26 | 38.33±6.46# |
| Isocarbophos | 24.61±6.56 | 18.12±5.73 | −4.12±0.58 | −6.33±0.56 | 39.53±6.12# |
| Isocarbophos+Vitamin B6 | 21.22±6.25 | 17.65±3.74 | −4.91±0.66 | −5.92±0.74 | 29.13±5.35* |
| Isocarbophos+Vitamin B6+Fingolimod | 22.34±5.63 | 16.73±4.66 | −4.82±0.69 | −6.61±0.76 | 37.86±6.92& |
After Isocarbophos treatment, arterial blood of offspring rats was collected from left ventricles for blood gas analysis. AB: actual bicarbonate; SB: standard bicarbonate; [BE(ecf)]: base excess extracellular fluid; [BE(B)]: base excess of blood; tCO2: total carbon dioxide. Data are expressed as the mean±SD, n = 8.
P<0.05 vs Saline group.
P<0.05 vs Isocarbophos group.
P<0.05 vs Isocarbophos+Vitamin B6.
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