Model-generated Probability of Death from Endocarditis by Age 60, Stratified by Age at Initiation of Injection Opioid Use and Injection Behavior Profile
| . | Probability of Endocarditis Death by Age 60 Years, % (rangea) . | |||||
|---|---|---|---|---|---|---|
| . | Began Use at Age 20 . | Began Use at Age 30 . | Began Use at Age 40 . | |||
| . | Female . | Male . | Female . | Male . | Female . | Male . |
| High frequency, higher infection risk | 54.4 (38.2–83.6) | 53.8 (37.7–83.1) | 52.0 (36.3–83.4) | 51.4 (35.9–82.8) | 45.2 (30.7–81.3) | 44.5 (30.2–80.5) |
| High frequency, lower infection risk | 3.8 (0–13.6) | 3.8 (13.4) | 3.1 (0–11.7) | 3.1 (0–11.6) | 2.2 (0–8.8) | 2.2 (0–8.7) |
| Low frequency, higher infection risk | 45.8 (31.1–90.7) | 44.9 (30.4–89.5) | 37.4 (23.3–84.0) | 36.8 (22.8–82.9) | 26.0 (13.7–68.8) | 25.6 (13.4–67.7) |
| Low frequency, lower infection risk | 2.5 (0–10.7) | 2.5 (0–10.4) | 1.9 (0–7.9) | 1.8 (0–7.8) | 1.2 (0–5.1) | 1.2 (0–5.1) |
| . | Probability of Endocarditis Death by Age 60 Years, % (rangea) . | |||||
|---|---|---|---|---|---|---|
| . | Began Use at Age 20 . | Began Use at Age 30 . | Began Use at Age 40 . | |||
| . | Female . | Male . | Female . | Male . | Female . | Male . |
| High frequency, higher infection risk | 54.4 (38.2–83.6) | 53.8 (37.7–83.1) | 52.0 (36.3–83.4) | 51.4 (35.9–82.8) | 45.2 (30.7–81.3) | 44.5 (30.2–80.5) |
| High frequency, lower infection risk | 3.8 (0–13.6) | 3.8 (13.4) | 3.1 (0–11.7) | 3.1 (0–11.6) | 2.2 (0–8.8) | 2.2 (0–8.7) |
| Low frequency, higher infection risk | 45.8 (31.1–90.7) | 44.9 (30.4–89.5) | 37.4 (23.3–84.0) | 36.8 (22.8–82.9) | 26.0 (13.7–68.8) | 25.6 (13.4–67.7) |
| Low frequency, lower infection risk | 2.5 (0–10.7) | 2.5 (0–10.4) | 1.9 (0–7.9) | 1.8 (0–7.8) | 1.2 (0–5.1) | 1.2 (0–5.1) |
High infection risk was defined as persons who do not clean their skin and reuse injection equipment; low infection risk was defined as persons who clean their skin and do not reuse injection equipment.
aRanges were determined by probabilistic sensitivity analysis.
Model-generated Probability of Death from Endocarditis by Age 60, Stratified by Age at Initiation of Injection Opioid Use and Injection Behavior Profile
| . | Probability of Endocarditis Death by Age 60 Years, % (rangea) . | |||||
|---|---|---|---|---|---|---|
| . | Began Use at Age 20 . | Began Use at Age 30 . | Began Use at Age 40 . | |||
| . | Female . | Male . | Female . | Male . | Female . | Male . |
| High frequency, higher infection risk | 54.4 (38.2–83.6) | 53.8 (37.7–83.1) | 52.0 (36.3–83.4) | 51.4 (35.9–82.8) | 45.2 (30.7–81.3) | 44.5 (30.2–80.5) |
| High frequency, lower infection risk | 3.8 (0–13.6) | 3.8 (13.4) | 3.1 (0–11.7) | 3.1 (0–11.6) | 2.2 (0–8.8) | 2.2 (0–8.7) |
| Low frequency, higher infection risk | 45.8 (31.1–90.7) | 44.9 (30.4–89.5) | 37.4 (23.3–84.0) | 36.8 (22.8–82.9) | 26.0 (13.7–68.8) | 25.6 (13.4–67.7) |
| Low frequency, lower infection risk | 2.5 (0–10.7) | 2.5 (0–10.4) | 1.9 (0–7.9) | 1.8 (0–7.8) | 1.2 (0–5.1) | 1.2 (0–5.1) |
| . | Probability of Endocarditis Death by Age 60 Years, % (rangea) . | |||||
|---|---|---|---|---|---|---|
| . | Began Use at Age 20 . | Began Use at Age 30 . | Began Use at Age 40 . | |||
| . | Female . | Male . | Female . | Male . | Female . | Male . |
| High frequency, higher infection risk | 54.4 (38.2–83.6) | 53.8 (37.7–83.1) | 52.0 (36.3–83.4) | 51.4 (35.9–82.8) | 45.2 (30.7–81.3) | 44.5 (30.2–80.5) |
| High frequency, lower infection risk | 3.8 (0–13.6) | 3.8 (13.4) | 3.1 (0–11.7) | 3.1 (0–11.6) | 2.2 (0–8.8) | 2.2 (0–8.7) |
| Low frequency, higher infection risk | 45.8 (31.1–90.7) | 44.9 (30.4–89.5) | 37.4 (23.3–84.0) | 36.8 (22.8–82.9) | 26.0 (13.7–68.8) | 25.6 (13.4–67.7) |
| Low frequency, lower infection risk | 2.5 (0–10.7) | 2.5 (0–10.4) | 1.9 (0–7.9) | 1.8 (0–7.8) | 1.2 (0–5.1) | 1.2 (0–5.1) |
High infection risk was defined as persons who do not clean their skin and reuse injection equipment; low infection risk was defined as persons who clean their skin and do not reuse injection equipment.
aRanges were determined by probabilistic sensitivity analysis.
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