Demographic and Clinical Characteristics of Patients With Necrotizing Soft-tissue Infections and Culture Data, Overall (n = 377) and by Presence (n = 118) or Absence (n = 259) of β-Hemolytic Streptococci
| Characteristic . | Patients, No. (%)a . | . | . |
|---|---|---|---|
| . | Total (n = 377) . | β-Hemolytic Streptococci . | . |
| . | . | Absent (n = 259) . | Present (n = 118) . |
| Male sex | 248 (65.8) | 164 (63.3) | 84 (71.2) |
| Age, median (IQR), y | 55.0 (44.0–62.0) | 56.0 (44.5–63.0) | 53.0 (43.3–60.8) |
| Race | |||
| White | 294 (78.0) | 202 (78.0) | 92 (78.0) |
| Black | 19 (5.0) | 14 (5.4) | 5 (4.2) |
| Native American | 11 (2.9) | 8 (3.1) | 3 (2.5) |
| Asian | 6 (1.6) | 4 (1.5) | 2 (1.7) |
| Other/unknown | 47 (12.5) | 31 (12.0) | 16 (13.6) |
| Transfer patient | 332 (88.1) | 238 (91.9) | 94 (79.7) |
| Preexisting conditions | |||
| Chronic renal failure | 26 (6.9) | 23 (8.9) | 3 (2.5) |
| Diabetes | 166 (44.0) | 117 (45.2) | 49 (41.5) |
| Cigarette smoking | 72 (19.1) | 53 (20.5) | 19 (16.1) |
| Drug abuse | 68 (18.0) | 44 (17.0) | 24 (20.3) |
| Body site(s) involved | |||
| Head | 8 (2.1) | 6 (2.3) | 2 (1.7) |
| Chest | 20 (5.3) | 13 (5.0) | 7 (5.9) |
| Arm | 64 (17.0) | 38 (14.7) | 26 (22.0) |
| Abdomen | 42 (11.1) | 40 (15.4) | 2 (1.7) |
| Perineum | 139 (36.9) | 111 (42.9) | 28 (23.7) |
| Leg | 124 (32.9) | 67 (25.9) | 57 (48.3) |
| Multiple sites | 19 (5.0) | 15 (5.8) | 4 (3.4) |
| Infection etiology | |||
| Boil/furuncle | 65 (17.2) | 50 (19.3) | 15 (12.7) |
| Trauma | 45 (11.9) | 20 (7.7) | 25 (21.2) |
| Chronic wound | 42 (11.1) | 23 (8.9) | 19 (16.1) |
| Injection drug use related | 48 (12.7) | 36 (13.9) | 12 (10.2) |
| Perirectal abscess | 17 (4.5) | 15 (5.8) | 2 (1.7) |
| Postoperative | 21 (5.6) | 18 (6.9) | 3 (2.5) |
| Idiopathic | 118 (31.3) | 83 (32.0) | 35 (29.7) |
| Other | 21 (5.7) | 13 (5.5) | 7 (5.8) |
| Polymicrobial infection | 275 (72.9) | 193 (74.5) | 83 (69.5) |
| Characteristic . | Patients, No. (%)a . | . | . |
|---|---|---|---|
| . | Total (n = 377) . | β-Hemolytic Streptococci . | . |
| . | . | Absent (n = 259) . | Present (n = 118) . |
| Male sex | 248 (65.8) | 164 (63.3) | 84 (71.2) |
| Age, median (IQR), y | 55.0 (44.0–62.0) | 56.0 (44.5–63.0) | 53.0 (43.3–60.8) |
| Race | |||
| White | 294 (78.0) | 202 (78.0) | 92 (78.0) |
| Black | 19 (5.0) | 14 (5.4) | 5 (4.2) |
| Native American | 11 (2.9) | 8 (3.1) | 3 (2.5) |
| Asian | 6 (1.6) | 4 (1.5) | 2 (1.7) |
| Other/unknown | 47 (12.5) | 31 (12.0) | 16 (13.6) |
| Transfer patient | 332 (88.1) | 238 (91.9) | 94 (79.7) |
| Preexisting conditions | |||
| Chronic renal failure | 26 (6.9) | 23 (8.9) | 3 (2.5) |
| Diabetes | 166 (44.0) | 117 (45.2) | 49 (41.5) |
| Cigarette smoking | 72 (19.1) | 53 (20.5) | 19 (16.1) |
| Drug abuse | 68 (18.0) | 44 (17.0) | 24 (20.3) |
| Body site(s) involved | |||
| Head | 8 (2.1) | 6 (2.3) | 2 (1.7) |
| Chest | 20 (5.3) | 13 (5.0) | 7 (5.9) |
| Arm | 64 (17.0) | 38 (14.7) | 26 (22.0) |
| Abdomen | 42 (11.1) | 40 (15.4) | 2 (1.7) |
| Perineum | 139 (36.9) | 111 (42.9) | 28 (23.7) |
| Leg | 124 (32.9) | 67 (25.9) | 57 (48.3) |
| Multiple sites | 19 (5.0) | 15 (5.8) | 4 (3.4) |
| Infection etiology | |||
| Boil/furuncle | 65 (17.2) | 50 (19.3) | 15 (12.7) |
| Trauma | 45 (11.9) | 20 (7.7) | 25 (21.2) |
| Chronic wound | 42 (11.1) | 23 (8.9) | 19 (16.1) |
| Injection drug use related | 48 (12.7) | 36 (13.9) | 12 (10.2) |
| Perirectal abscess | 17 (4.5) | 15 (5.8) | 2 (1.7) |
| Postoperative | 21 (5.6) | 18 (6.9) | 3 (2.5) |
| Idiopathic | 118 (31.3) | 83 (32.0) | 35 (29.7) |
| Other | 21 (5.7) | 13 (5.5) | 7 (5.8) |
| Polymicrobial infection | 275 (72.9) | 193 (74.5) | 83 (69.5) |
Abbreviation: IQR, interquartile range.
aData represent no. (%) of patients unless otherwise specified.
Demographic and Clinical Characteristics of Patients With Necrotizing Soft-tissue Infections and Culture Data, Overall (n = 377) and by Presence (n = 118) or Absence (n = 259) of β-Hemolytic Streptococci
| Characteristic . | Patients, No. (%)a . | . | . |
|---|---|---|---|
| . | Total (n = 377) . | β-Hemolytic Streptococci . | . |
| . | . | Absent (n = 259) . | Present (n = 118) . |
| Male sex | 248 (65.8) | 164 (63.3) | 84 (71.2) |
| Age, median (IQR), y | 55.0 (44.0–62.0) | 56.0 (44.5–63.0) | 53.0 (43.3–60.8) |
| Race | |||
| White | 294 (78.0) | 202 (78.0) | 92 (78.0) |
| Black | 19 (5.0) | 14 (5.4) | 5 (4.2) |
| Native American | 11 (2.9) | 8 (3.1) | 3 (2.5) |
| Asian | 6 (1.6) | 4 (1.5) | 2 (1.7) |
| Other/unknown | 47 (12.5) | 31 (12.0) | 16 (13.6) |
| Transfer patient | 332 (88.1) | 238 (91.9) | 94 (79.7) |
| Preexisting conditions | |||
| Chronic renal failure | 26 (6.9) | 23 (8.9) | 3 (2.5) |
| Diabetes | 166 (44.0) | 117 (45.2) | 49 (41.5) |
| Cigarette smoking | 72 (19.1) | 53 (20.5) | 19 (16.1) |
| Drug abuse | 68 (18.0) | 44 (17.0) | 24 (20.3) |
| Body site(s) involved | |||
| Head | 8 (2.1) | 6 (2.3) | 2 (1.7) |
| Chest | 20 (5.3) | 13 (5.0) | 7 (5.9) |
| Arm | 64 (17.0) | 38 (14.7) | 26 (22.0) |
| Abdomen | 42 (11.1) | 40 (15.4) | 2 (1.7) |
| Perineum | 139 (36.9) | 111 (42.9) | 28 (23.7) |
| Leg | 124 (32.9) | 67 (25.9) | 57 (48.3) |
| Multiple sites | 19 (5.0) | 15 (5.8) | 4 (3.4) |
| Infection etiology | |||
| Boil/furuncle | 65 (17.2) | 50 (19.3) | 15 (12.7) |
| Trauma | 45 (11.9) | 20 (7.7) | 25 (21.2) |
| Chronic wound | 42 (11.1) | 23 (8.9) | 19 (16.1) |
| Injection drug use related | 48 (12.7) | 36 (13.9) | 12 (10.2) |
| Perirectal abscess | 17 (4.5) | 15 (5.8) | 2 (1.7) |
| Postoperative | 21 (5.6) | 18 (6.9) | 3 (2.5) |
| Idiopathic | 118 (31.3) | 83 (32.0) | 35 (29.7) |
| Other | 21 (5.7) | 13 (5.5) | 7 (5.8) |
| Polymicrobial infection | 275 (72.9) | 193 (74.5) | 83 (69.5) |
| Characteristic . | Patients, No. (%)a . | . | . |
|---|---|---|---|
| . | Total (n = 377) . | β-Hemolytic Streptococci . | . |
| . | . | Absent (n = 259) . | Present (n = 118) . |
| Male sex | 248 (65.8) | 164 (63.3) | 84 (71.2) |
| Age, median (IQR), y | 55.0 (44.0–62.0) | 56.0 (44.5–63.0) | 53.0 (43.3–60.8) |
| Race | |||
| White | 294 (78.0) | 202 (78.0) | 92 (78.0) |
| Black | 19 (5.0) | 14 (5.4) | 5 (4.2) |
| Native American | 11 (2.9) | 8 (3.1) | 3 (2.5) |
| Asian | 6 (1.6) | 4 (1.5) | 2 (1.7) |
| Other/unknown | 47 (12.5) | 31 (12.0) | 16 (13.6) |
| Transfer patient | 332 (88.1) | 238 (91.9) | 94 (79.7) |
| Preexisting conditions | |||
| Chronic renal failure | 26 (6.9) | 23 (8.9) | 3 (2.5) |
| Diabetes | 166 (44.0) | 117 (45.2) | 49 (41.5) |
| Cigarette smoking | 72 (19.1) | 53 (20.5) | 19 (16.1) |
| Drug abuse | 68 (18.0) | 44 (17.0) | 24 (20.3) |
| Body site(s) involved | |||
| Head | 8 (2.1) | 6 (2.3) | 2 (1.7) |
| Chest | 20 (5.3) | 13 (5.0) | 7 (5.9) |
| Arm | 64 (17.0) | 38 (14.7) | 26 (22.0) |
| Abdomen | 42 (11.1) | 40 (15.4) | 2 (1.7) |
| Perineum | 139 (36.9) | 111 (42.9) | 28 (23.7) |
| Leg | 124 (32.9) | 67 (25.9) | 57 (48.3) |
| Multiple sites | 19 (5.0) | 15 (5.8) | 4 (3.4) |
| Infection etiology | |||
| Boil/furuncle | 65 (17.2) | 50 (19.3) | 15 (12.7) |
| Trauma | 45 (11.9) | 20 (7.7) | 25 (21.2) |
| Chronic wound | 42 (11.1) | 23 (8.9) | 19 (16.1) |
| Injection drug use related | 48 (12.7) | 36 (13.9) | 12 (10.2) |
| Perirectal abscess | 17 (4.5) | 15 (5.8) | 2 (1.7) |
| Postoperative | 21 (5.6) | 18 (6.9) | 3 (2.5) |
| Idiopathic | 118 (31.3) | 83 (32.0) | 35 (29.7) |
| Other | 21 (5.7) | 13 (5.5) | 7 (5.8) |
| Polymicrobial infection | 275 (72.9) | 193 (74.5) | 83 (69.5) |
Abbreviation: IQR, interquartile range.
aData represent no. (%) of patients unless otherwise specified.
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