Table 3. Open in new tab HRQOL of KTRs...

References	Patient characteristics	Effect measure	HRQOL using SF-36 and KDQOL	HRQOL using WHOQOL or QLI-DT
KTRs versus patients on dialysis
Czyzewski et al. [37]	–	55	–	3	–	58	HD	78	Mean (KT/D)	45/35^b	72/50^b	42/30	78/46	45/28	45/44	58/49	70/59	65/47	64/61	85/66^b	76/54^b	48/30^b
					–	50	PD	40		45/38^b	72/52^b	42/36	78/66	45/42	45/50	58/68	70/74	65/74	64/50	85/74^b	77/65^b	48/54^b
				12	–	58	HD	78		46/35^b	76/50^b	50/30	67/46	44/28^b	44/44	56/49^b	70/59	65/48	63/61	83/66^b	78/54^b	56/30^b
					–	50	PD	40		46/38^b	76/52^b	50/36	67/66	44/42	44/50	56/68	70/74	65/74	63/50	83/74	79/65	53/54^b
Sayin et al. [33]	33	65	70	41	47	72	HD	46	Mean (KT/D)		69/56	43/41	64/63	50/40		68/56^g	58/63	46/30	66/58
					46	61	PD	35		69/56	43/39	64/66	50/41		68/52^g	58/56	46/46	66/61
Zheng et al. [38]	34	78	100	39^a	–	–	HD	>3	Mean (KT/D)		80/68^d	74/35^d	72/62^d	67/40^d		64/46^d	75/55^d	77/42^d	72/59^d
Tamura et al. [34]	52	60	100	47^a	53	48	HD	–	Mean (KT/D)		47/23^c	46/20^c	49/43^c	45/40^c		51/41^c	49/38^c	48/35^c	52/49^c
Fujisawa et al. [32]	44	43	74	126	46	69	HD	92	Mean (KT/D)		86/82	78/64^b	80/67^b	56/52		63/58	82/74^b	78/70	70/69
Karine et al. [39]	55	61	–	–	69	65	D	>12	Mean (KT/D)	45/35^d					46/40^d
Iqbal et al. [40]	39	–	–	>6	43	–	HD	>3	Mean (KT/D)		91/37^f	30/0^f	69/30^f	48/21^f	–	66/40^f	70/24^f	33/0^f	56/41^f
Ranabhat et al. [30]	39	75	–	>6	44	75	HD	>3	Mean (KT/D)														13/11^d	14/11^d	14/13^b	12/11^c	13/11^d
Sapkota et al. [36]	41	70	–	72%: 3–24^h	46	68	HD	76%: 3–24^h	Mean (KT/D)														70/49^d	69/52^d	69/58^d	60/56^d	267/215^d
Tomasz and Piotr [31]	43	52	–	35	58	61	HD	41	Mean (KT/D)														14/12^e	14/13	14/13^e	13/13	14/12^e
Rambod et al. [35]	51	56	–	>3	50	48	HD	>3	Mean (KT/D)														21/19^d	18/21	19/18	24/25^b	21/20^b
KTRs versus patients on dialysis and on the WL
Rosenberger et al. [41]	47	56	–	3	49	58	D	42	Mean (KT/WL)	52/48					60/57
				12						54/50					63/62
Kovacs et al. [42]	49	58	–	54	49	60	D	36	Beta- coeeficient		0.01	–	–	0.16^d		0.03	–	–	−0.001	0.04	0.22^d	0.18^c
Fujisawa, et al. [32]	44	43	74	126	46	76	HD	120	Mean (KT/WL)		86/82	78/74	80/74	56/50^b		63/61	82/75	78/80	70/68
Franke et al. [43]	48	62	–	56	48	62	D	65	Mean (KT/WL)														7/5^b	6/5^b	7/6^b	7/6	7/6^b
Neipp et al. [44]	55	63	–	234	43^a	72	–	–	Mean (KT/WL)														6/5^f	5/4^f	5/4^f	6/6	5/5
KTRs versus patients with CKD not receiving RRT
Iqbal et al. [40]	39	–	–	>6	49	–	CKD 3–5	Mean (KT/WL)		91/69^f	–	49/44^f	48/31^f		66/51^f	–	–	–
Karine et al. [39]	55	61	–	–	66	68	CKD 3b	Mean (KT/WL)	45/43^f						46/48^f
					68	63	CKD 4–5	45/40^f						46/47^f
Stomer et al. [48]	56	61	–	169	57	61	CKD 3b–4	Mean (KT/CKD)	43/43					50/52

References

Patient characteristics

Effect measure

HRQOL using SF-36 and KDQOL

HRQOL using WHOQOL or QLI-DT

KTRs

Patients on dialysis/with CKD

Physical

Mental

Disease-specific

Mean age (years)

Male, %

LDKT, %

Time after KT (minutes)

Mean age (years)

Male, %

RRT

Time on dialysis (months)

PCS

MCS

EKD

BKD

PHY

PSY

SOC

ENV/FAM

Total

KTRs versus patients on dialysis

Czyzewski et al. [37]

–

Mean

(KT/D)

45/35^b

72/50^b

42/30

78/46

45/28

45/44

58/49

70/59

65/47

64/61

85/66^b

76/54^b

48/30^b

–

45/38^b

72/52^b

42/36

78/66

45/42

45/50

58/68

70/74

65/74

64/50

85/74^b

77/65^b

48/54^b

–

46/35^b

76/50^b

50/30

67/46

44/28^b

44/44

56/49^b

70/59

65/48

63/61

83/66^b

78/54^b

56/30^b

–

46/38^b

76/52^b

50/36

67/66

44/42

44/50

56/68

70/74

65/74

63/50

83/74

79/65

53/54^b

Sayin et al. [33]

Mean

(KT/D)

69/56

43/41

64/63

50/40

68/56^g

58/63

46/30

66/58

69/56

43/39

64/66

50/41

68/52^g

58/56

46/46

66/61

Zheng et al. [38]

100

39^a

–

Mean

(KT/D)

80/68^d

74/35^d

72/62^d

67/40^d

64/46^d

75/55^d

77/42^d

72/59^d

Tamura et al. [34]

100

47^a

–

Mean

(KT/D)

47/23^c

46/20^c

49/43^c

45/40^c

51/41^c

49/38^c

48/35^c

52/49^c

Fujisawa et al. [32]

126

Mean

(KT/D)

86/82

78/64^b

80/67^b

56/52

63/58

82/74^b

78/70

70/69

Karine et al. [39]

–

>12

Mean

(KT/D)

45/35^d

46/40^d

Iqbal et al. [40]

–

Mean

(KT/D)

91/37^f

30/0^f

69/30^f

48/21^f

–

66/40^f

70/24^f

33/0^f

56/41^f

Ranabhat et al. [30]

–

Mean

(KT/D)

13/11^d

14/11^d

14/13^b

12/11^c

13/11^d

Sapkota et al. [36]

–

72%:

3–24^h

76%:

3–24^h

Mean

(KT/D)

70/49^d

69/52^d

69/58^d

60/56^d

267/215^d

Tomasz and Piotr [31]

–

Mean

(KT/D)

14/12^e

14/13

14/13^e

13/13

14/12^e

Rambod et al. [35]

–

Mean

(KT/D)

21/19^d

18/21

19/18

24/25^b

21/20^b

KTRs versus patients on dialysis and on the WL

Rosenberger et al. [41]

–

Mean

(KT/WL)

52/48

60/57

54/50

63/62

Kovacs et al. [42]

–

Beta- coeeficient

0.01

–

0.16^d

0.03

–

−0.001

0.04

0.22^d

0.18^c

Fujisawa, et al. [32]

126

120

Mean

(KT/WL)

86/82

78/74

80/74

56/50^b

63/61

82/75

78/80

70/68

Franke et al. [43]

–

Mean

(KT/WL)

7/5^b

6/5^b

7/6^b

7/6

7/6^b

Neipp et al. [44]

–

234

43^a

–

Mean

(KT/WL)

6/5^f

5/4^f

6/6

5/5

KTRs versus patients with CKD not receiving RRT

Iqbal et al. [40]

–

CKD 3–5

Mean

(KT/WL)

91/69^f

–

49/44^f

48/31^f

66/51^f

–

Karine et al. [39]

–

CKD 3b

Mean

(KT/WL)

45/43^f

46/48^f

CKD 4–5

45/40^f

46/47^f

Stomer et al. [48]

–

169

CKD 3b–4

Mean

(KT/CKD)

43/43

50/52

References	Patient characteristics	Effect measure	HRQOL using SF-36 and KDQOL	HRQOL using WHOQOL or QLI-DT
KTRs versus patients on dialysis
Czyzewski et al. [37]	–	55	–	3	–	58	HD	78	Mean (KT/D)	45/35^b	72/50^b	42/30	78/46	45/28	45/44	58/49	70/59	65/47	64/61	85/66^b	76/54^b	48/30^b
					–	50	PD	40		45/38^b	72/52^b	42/36	78/66	45/42	45/50	58/68	70/74	65/74	64/50	85/74^b	77/65^b	48/54^b
				12	–	58	HD	78		46/35^b	76/50^b	50/30	67/46	44/28^b	44/44	56/49^b	70/59	65/48	63/61	83/66^b	78/54^b	56/30^b
					–	50	PD	40		46/38^b	76/52^b	50/36	67/66	44/42	44/50	56/68	70/74	65/74	63/50	83/74	79/65	53/54^b
Sayin et al. [33]	33	65	70	41	47	72	HD	46	Mean (KT/D)		69/56	43/41	64/63	50/40		68/56^g	58/63	46/30	66/58
					46	61	PD	35		69/56	43/39	64/66	50/41		68/52^g	58/56	46/46	66/61
Zheng et al. [38]	34	78	100	39^a	–	–	HD	>3	Mean (KT/D)		80/68^d	74/35^d	72/62^d	67/40^d		64/46^d	75/55^d	77/42^d	72/59^d
Tamura et al. [34]	52	60	100	47^a	53	48	HD	–	Mean (KT/D)		47/23^c	46/20^c	49/43^c	45/40^c		51/41^c	49/38^c	48/35^c	52/49^c
Fujisawa et al. [32]	44	43	74	126	46	69	HD	92	Mean (KT/D)		86/82	78/64^b	80/67^b	56/52		63/58	82/74^b	78/70	70/69
Karine et al. [39]	55	61	–	–	69	65	D	>12	Mean (KT/D)	45/35^d					46/40^d
Iqbal et al. [40]	39	–	–	>6	43	–	HD	>3	Mean (KT/D)		91/37^f	30/0^f	69/30^f	48/21^f	–	66/40^f	70/24^f	33/0^f	56/41^f
Ranabhat et al. [30]	39	75	–	>6	44	75	HD	>3	Mean (KT/D)														13/11^d	14/11^d	14/13^b	12/11^c	13/11^d
Sapkota et al. [36]	41	70	–	72%: 3–24^h	46	68	HD	76%: 3–24^h	Mean (KT/D)														70/49^d	69/52^d	69/58^d	60/56^d	267/215^d
Tomasz and Piotr [31]	43	52	–	35	58	61	HD	41	Mean (KT/D)														14/12^e	14/13	14/13^e	13/13	14/12^e
Rambod et al. [35]	51	56	–	>3	50	48	HD	>3	Mean (KT/D)														21/19^d	18/21	19/18	24/25^b	21/20^b
KTRs versus patients on dialysis and on the WL
Rosenberger et al. [41]	47	56	–	3	49	58	D	42	Mean (KT/WL)	52/48					60/57
				12						54/50					63/62
Kovacs et al. [42]	49	58	–	54	49	60	D	36	Beta- coeeficient		0.01	–	–	0.16^d		0.03	–	–	−0.001	0.04	0.22^d	0.18^c
Fujisawa, et al. [32]	44	43	74	126	46	76	HD	120	Mean (KT/WL)		86/82	78/74	80/74	56/50^b		63/61	82/75	78/80	70/68
Franke et al. [43]	48	62	–	56	48	62	D	65	Mean (KT/WL)														7/5^b	6/5^b	7/6^b	7/6	7/6^b
Neipp et al. [44]	55	63	–	234	43^a	72	–	–	Mean (KT/WL)														6/5^f	5/4^f	5/4^f	6/6	5/5
KTRs versus patients with CKD not receiving RRT
Iqbal et al. [40]	39	–	–	>6	49	–	CKD 3–5	Mean (KT/WL)		91/69^f	–	49/44^f	48/31^f		66/51^f	–	–	–
Karine et al. [39]	55	61	–	–	66	68	CKD 3b	Mean (KT/WL)	45/43^f						46/48^f
					68	63	CKD 4–5	45/40^f						46/47^f
Stomer et al. [48]	56	61	–	169	57	61	CKD 3b–4	Mean (KT/CKD)	43/43					50/52

References

Patient characteristics

Effect measure

HRQOL using SF-36 and KDQOL

HRQOL using WHOQOL or QLI-DT

KTRs

Patients on dialysis/with CKD

Physical

Mental

Disease-specific

Mean age (years)

Male, %

LDKT, %

Time after KT (minutes)

Mean age (years)

Male, %

RRT

Time on dialysis (months)

PCS

MCS

EKD

BKD

PHY

PSY

SOC

ENV/FAM

Total

KTRs versus patients on dialysis

Czyzewski et al. [37]

–

Mean

(KT/D)

45/35^b

72/50^b

42/30

78/46

45/28

45/44

58/49

70/59

65/47

64/61

85/66^b

76/54^b

48/30^b

–

45/38^b

72/52^b

42/36

78/66

45/42

45/50

58/68

70/74

65/74

64/50

85/74^b

77/65^b

48/54^b

–

46/35^b

76/50^b

50/30

67/46

44/28^b

44/44

56/49^b

70/59

65/48

63/61

83/66^b

78/54^b

56/30^b

–

46/38^b

76/52^b

50/36

67/66

44/42

44/50

56/68

70/74

65/74

63/50

83/74

79/65

53/54^b

Sayin et al. [33]

Mean

(KT/D)

69/56

43/41

64/63

50/40

68/56^g

58/63

46/30

66/58

69/56

43/39

64/66

50/41

68/52^g

58/56

46/46

66/61

Zheng et al. [38]

100

39^a

–

Mean

(KT/D)

80/68^d

74/35^d

72/62^d

67/40^d

64/46^d

75/55^d

77/42^d

72/59^d

Tamura et al. [34]

100

47^a

–

Mean

(KT/D)

47/23^c

46/20^c

49/43^c

45/40^c

51/41^c

49/38^c

48/35^c

52/49^c

Fujisawa et al. [32]

126

Mean

(KT/D)

86/82

78/64^b

80/67^b

56/52

63/58

82/74^b

78/70

70/69

Karine et al. [39]

–

>12

Mean

(KT/D)

45/35^d

46/40^d

Iqbal et al. [40]

–

Mean

(KT/D)

91/37^f

30/0^f

69/30^f

48/21^f

–

66/40^f

70/24^f

33/0^f

56/41^f

Ranabhat et al. [30]

–

Mean

(KT/D)

13/11^d

14/11^d

14/13^b

12/11^c

13/11^d

Sapkota et al. [36]

–

72%:

3–24^h

76%:

3–24^h

Mean

(KT/D)

70/49^d

69/52^d

69/58^d

60/56^d

267/215^d

Tomasz and Piotr [31]

–

Mean

(KT/D)

14/12^e

14/13

14/13^e

13/13

14/12^e

Rambod et al. [35]

–

Mean

(KT/D)

21/19^d

18/21

19/18

24/25^b

21/20^b

KTRs versus patients on dialysis and on the WL

Rosenberger et al. [41]

–

Mean

(KT/WL)

52/48

60/57

54/50

63/62

Kovacs et al. [42]

–

Beta- coeeficient

0.01

–

0.16^d

0.03

–

−0.001

0.04

0.22^d

0.18^c

Fujisawa, et al. [32]

126

120

Mean

(KT/WL)

86/82

78/74

80/74

56/50^b

63/61

82/75

78/80

70/68

Franke et al. [43]

–

Mean

(KT/WL)

7/5^b

6/5^b

7/6^b

7/6

7/6^b

Neipp et al. [44]

–

234

43^a

–

Mean

(KT/WL)

6/5^f

5/4^f

6/6

5/5

KTRs versus patients with CKD not receiving RRT

Iqbal et al. [40]

–

CKD 3–5

Mean

(KT/WL)

91/69^f

–

49/44^f

48/31^f

66/51^f

–

Karine et al. [39]

–

CKD 3b

Mean

(KT/WL)

45/43^f

46/48^f

CKD 4–5

45/40^f

46/47^f

Stomer et al. [48]

–

169

CKD 3b–4

Mean

(KT/CKD)

43/43

50/52

Table 3.

Open in new tab

HRQOL of KTRs compared with patients on dialysis (n = 11), patients on the WL (n = 5) and patients with CKD not receiving RRT (n = 3)

References	Patient characteristics								Effect measure	HRQOL using SF-36 and KDQOL													HRQOL using WHOQOL or QLI-DT
	KTRs				Patients on dialysis/with CKD					Physical					Mental					Disease-specific
	Mean age (years)	Male, %	LDKT, %	Time after KT (minutes)	Mean age (years)	Male, %	RRT	Time on dialysis (months)		PCS	PF	RP	BP	GH	MCS	VT	SF	RE	MH	S	EKD	BKD	PHY	PSY	SOC	ENV/FAM	Total
KTRs versus patients on dialysis
Czyzewski et al. [37]	–	55	–	3	–	58	HD	78	Mean (KT/D)	45/35^b	72/50^b	42/30	78/46	45/28	45/44	58/49	70/59	65/47	64/61	85/66^b	76/54^b	48/30^b
					–	50	PD	40		45/38^b	72/52^b	42/36	78/66	45/42	45/50	58/68	70/74	65/74	64/50	85/74^b	77/65^b	48/54^b
				12	–	58	HD	78		46/35^b	76/50^b	50/30	67/46	44/28^b	44/44	56/49^b	70/59	65/48	63/61	83/66^b	78/54^b	56/30^b
					–	50	PD	40		46/38^b	76/52^b	50/36	67/66	44/42	44/50	56/68	70/74	65/74	63/50	83/74	79/65	53/54^b
Sayin et al. [33]	33	65	70	41	47	72	HD	46	Mean (KT/D)		69/56	43/41	64/63	50/40		68/56^g	58/63	46/30	66/58
					46	61	PD	35	Mean (KT/D)		69/56	43/39	64/66	50/41		68/52^g	58/56	46/46	66/61
Zheng et al. [38]	34	78	100	39^a	–	–	HD	>3	Mean (KT/D)		80/68^d	74/35^d	72/62^d	67/40^d		64/46^d	75/55^d	77/42^d	72/59^d
Tamura et al. [34]	52	60	100	47^a	53	48	HD	–	Mean (KT/D)		47/23^c	46/20^c	49/43^c	45/40^c		51/41^c	49/38^c	48/35^c	52/49^c
Fujisawa et al. [32]	44	43	74	126	46	69	HD	92	Mean (KT/D)		86/82	78/64^b	80/67^b	56/52		63/58	82/74^b	78/70	70/69
Karine et al. [39]	55	61	–	–	69	65	D	>12	Mean (KT/D)	45/35^d					46/40^d
Iqbal et al. [40]	39	–	–	>6	43	–	HD	>3	Mean (KT/D)		91/37^f	30/0^f	69/30^f	48/21^f	–	66/40^f	70/24^f	33/0^f	56/41^f
Ranabhat et al. [30]	39	75	–	>6	44	75	HD	>3	Mean (KT/D)														13/11^d	14/11^d	14/13^b	12/11^c	13/11^d
Sapkota et al. [36]	41	70	–	72%: 3–24^h	46	68	HD	76%: 3–24^h	Mean (KT/D)														70/49^d	69/52^d	69/58^d	60/56^d	267/215^d
Tomasz and Piotr [31]	43	52	–	35	58	61	HD	41	Mean (KT/D)														14/12^e	14/13	14/13^e	13/13	14/12^e
Rambod et al. [35]	51	56	–	>3	50	48	HD	>3	Mean (KT/D)														21/19^d	18/21	19/18	24/25^b	21/20^b
KTRs versus patients on dialysis and on the WL
Rosenberger et al. [41]	47	56	–	3	49	58	D	42	Mean (KT/WL)	52/48					60/57
				12						54/50					63/62
Kovacs et al. [42]	49	58	–	54	49	60	D	36	Beta- coeeficient		0.01	–	–	0.16^d		0.03	–	–	−0.001	0.04	0.22^d	0.18^c
Fujisawa, et al. [32]	44	43	74	126	46	76	HD	120	Mean (KT/WL)		86/82	78/74	80/74	56/50^b		63/61	82/75	78/80	70/68
Franke et al. [43]	48	62	–	56	48	62	D	65	Mean (KT/WL)														7/5^b	6/5^b	7/6^b	7/6	7/6^b
Neipp et al. [44]	55	63	–	234	43^a	72	–	–	Mean (KT/WL)														6/5^f	5/4^f	5/4^f	6/6	5/5
KTRs versus patients with CKD not receiving RRT
Iqbal et al. [40]	39	–	–	>6	49	–	CKD 3–5		Mean (KT/WL)		91/69^f	–	49/44^f	48/31^f		66/51^f	–	–	–
Karine et al. [39]	55	61	–	–	66	68	CKD 3b		Mean (KT/WL)	45/43^f						46/48^f
					68	63	CKD 4–5		Mean (KT/WL)	45/40^f						46/47^f
Stomer et al. [48]	56	61	–	169	57	61	CKD 3b–4		Mean (KT/CKD)	43/43					50/52

References	Patient characteristics								Effect measure	HRQOL using SF-36 and KDQOL													HRQOL using WHOQOL or QLI-DT
	KTRs				Patients on dialysis/with CKD					Physical					Mental					Disease-specific
	Mean age (years)	Male, %	LDKT, %	Time after KT (minutes)	Mean age (years)	Male, %	RRT	Time on dialysis (months)		PCS	PF	RP	BP	GH	MCS	VT	SF	RE	MH	S	EKD	BKD	PHY	PSY	SOC	ENV/FAM	Total
KTRs versus patients on dialysis
Czyzewski et al. [37]	–	55	–	3	–	58	HD	78	Mean (KT/D)	45/35^b	72/50^b	42/30	78/46	45/28	45/44	58/49	70/59	65/47	64/61	85/66^b	76/54^b	48/30^b
					–	50	PD	40		45/38^b	72/52^b	42/36	78/66	45/42	45/50	58/68	70/74	65/74	64/50	85/74^b	77/65^b	48/54^b
				12	–	58	HD	78		46/35^b	76/50^b	50/30	67/46	44/28^b	44/44	56/49^b	70/59	65/48	63/61	83/66^b	78/54^b	56/30^b
					–	50	PD	40		46/38^b	76/52^b	50/36	67/66	44/42	44/50	56/68	70/74	65/74	63/50	83/74	79/65	53/54^b
Sayin et al. [33]	33	65	70	41	47	72	HD	46	Mean (KT/D)		69/56	43/41	64/63	50/40		68/56^g	58/63	46/30	66/58
					46	61	PD	35	Mean (KT/D)		69/56	43/39	64/66	50/41		68/52^g	58/56	46/46	66/61
Zheng et al. [38]	34	78	100	39^a	–	–	HD	>3	Mean (KT/D)		80/68^d	74/35^d	72/62^d	67/40^d		64/46^d	75/55^d	77/42^d	72/59^d
Tamura et al. [34]	52	60	100	47^a	53	48	HD	–	Mean (KT/D)		47/23^c	46/20^c	49/43^c	45/40^c		51/41^c	49/38^c	48/35^c	52/49^c
Fujisawa et al. [32]	44	43	74	126	46	69	HD	92	Mean (KT/D)		86/82	78/64^b	80/67^b	56/52		63/58	82/74^b	78/70	70/69
Karine et al. [39]	55	61	–	–	69	65	D	>12	Mean (KT/D)	45/35^d					46/40^d
Iqbal et al. [40]	39	–	–	>6	43	–	HD	>3	Mean (KT/D)		91/37^f	30/0^f	69/30^f	48/21^f	–	66/40^f	70/24^f	33/0^f	56/41^f
Ranabhat et al. [30]	39	75	–	>6	44	75	HD	>3	Mean (KT/D)														13/11^d	14/11^d	14/13^b	12/11^c	13/11^d
Sapkota et al. [36]	41	70	–	72%: 3–24^h	46	68	HD	76%: 3–24^h	Mean (KT/D)														70/49^d	69/52^d	69/58^d	60/56^d	267/215^d
Tomasz and Piotr [31]	43	52	–	35	58	61	HD	41	Mean (KT/D)														14/12^e	14/13	14/13^e	13/13	14/12^e
Rambod et al. [35]	51	56	–	>3	50	48	HD	>3	Mean (KT/D)														21/19^d	18/21	19/18	24/25^b	21/20^b
KTRs versus patients on dialysis and on the WL
Rosenberger et al. [41]	47	56	–	3	49	58	D	42	Mean (KT/WL)	52/48					60/57
				12						54/50					63/62
Kovacs et al. [42]	49	58	–	54	49	60	D	36	Beta- coeeficient		0.01	–	–	0.16^d		0.03	–	–	−0.001	0.04	0.22^d	0.18^c
Fujisawa, et al. [32]	44	43	74	126	46	76	HD	120	Mean (KT/WL)		86/82	78/74	80/74	56/50^b		63/61	82/75	78/80	70/68
Franke et al. [43]	48	62	–	56	48	62	D	65	Mean (KT/WL)														7/5^b	6/5^b	7/6^b	7/6	7/6^b
Neipp et al. [44]	55	63	–	234	43^a	72	–	–	Mean (KT/WL)														6/5^f	5/4^f	5/4^f	6/6	5/5
KTRs versus patients with CKD not receiving RRT
Iqbal et al. [40]	39	–	–	>6	49	–	CKD 3–5		Mean (KT/WL)		91/69^f	–	49/44^f	48/31^f		66/51^f	–	–	–
Karine et al. [39]	55	61	–	–	66	68	CKD 3b		Mean (KT/WL)	45/43^f						46/48^f
					68	63	CKD 4–5		Mean (KT/WL)	45/40^f						46/47^f
Stomer et al. [48]	56	61	–	169	57	61	CKD 3b–4		Mean (KT/CKD)	43/43					50/52

Continuous variables are presented as the mean if not otherwise indicated. HRQOL results are presented in bold if they were reportedly significant according to statistical testing (P < 0.05). –, not reported; D, dialysis; S, symptom. ^aValues presented as median. ^bP < 0.05. ^cP < 0.01. ^dP < 0.001. ^eP < 0.0001. ^fP-value not reported. ^gStatistical test conducted for comparison across more than two groups (KTRs, HD and PD) and P < 0.05. ^hPercentage within the indicated range.

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