Table 4.

Median costs according to surgical intervention (n = 3913) and risk stratification

CostsTotal cohort, $Low risk, $High risk, $PaHigh-low estimate (95% CI), $b
Total 90-day costs
 1 endoscopy49 86249 12649 862.42−5302 (−18 440 to 7837)
 2 endoscopies70 76771 34366 821.952105 (−18 117 to 22 328)
 NU only44 93337 68547 775<.001−9826 (−13 956 to −5695)
 1 endoscopy + NU60 32455 20361 683<.001−6849 (−10 359 to −3339)
 2 endoscopies + NU76 18680 21974 293.472928 (−4868 to 10 723)
Total 180-day costs
 1 endoscopy56 47055 43358 300.20−12 853 (−30 849 to 5142)
 2 endoscopies85 09385 09385 674.49−8206 (−33 909 to 17 497)
 NU only58 72941 78663 747<.001−20 344 (−26 746 to −13 941)
 1 endoscopy + NU76 61566 86680 029<.001−14 385 (−18 982 to− 9788)
 2 endoscopies + NU97 91897 64498 295.52−3271 (−13 238 to 6697)
Total 365-day costs
 1 endoscopy72 46369 41677 929.21−15 196 (−38 022 to 7630)
 2 endoscopies104 50898 090111 096.55−8600 (−41 096 to 23 897)
 NU only81 78760 93489 613<.001−27 879 (−37 644 to −18 114)
 1 endoscopy + NU103 77083 847111 880<.001−26 491 (−33 090 to −19 892)
 2 endoscopies + NU126 895119 294131 067.13−10 682 (−24 444 to 3081)
CostsTotal cohort, $Low risk, $High risk, $PaHigh-low estimate (95% CI), $b
Total 90-day costs
 1 endoscopy49 86249 12649 862.42−5302 (−18 440 to 7837)
 2 endoscopies70 76771 34366 821.952105 (−18 117 to 22 328)
 NU only44 93337 68547 775<.001−9826 (−13 956 to −5695)
 1 endoscopy + NU60 32455 20361 683<.001−6849 (−10 359 to −3339)
 2 endoscopies + NU76 18680 21974 293.472928 (−4868 to 10 723)
Total 180-day costs
 1 endoscopy56 47055 43358 300.20−12 853 (−30 849 to 5142)
 2 endoscopies85 09385 09385 674.49−8206 (−33 909 to 17 497)
 NU only58 72941 78663 747<.001−20 344 (−26 746 to −13 941)
 1 endoscopy + NU76 61566 86680 029<.001−14 385 (−18 982 to− 9788)
 2 endoscopies + NU97 91897 64498 295.52−3271 (−13 238 to 6697)
Total 365-day costs
 1 endoscopy72 46369 41677 929.21−15 196 (−38 022 to 7630)
 2 endoscopies104 50898 090111 096.55−8600 (−41 096 to 23 897)
 NU only81 78760 93489 613<.001−27 879 (−37 644 to −18 114)
 1 endoscopy + NU103 77083 847111 880<.001−26 491 (−33 090 to −19 892)
 2 endoscopies + NU126 895119 294131 067.13−10 682 (−24 444 to 3081)
a

P values calculated with a 2-sample Wilcoxon test to evaluate the difference between groups. All statistical tests were 2-sided. CI = confidence interval; NU = nephroureterectomy.

b

Difference between low- and high-risk groups (high-low estimate, 95% CI) in 2020 US dollars.

Table 4.

Median costs according to surgical intervention (n = 3913) and risk stratification

CostsTotal cohort, $Low risk, $High risk, $PaHigh-low estimate (95% CI), $b
Total 90-day costs
 1 endoscopy49 86249 12649 862.42−5302 (−18 440 to 7837)
 2 endoscopies70 76771 34366 821.952105 (−18 117 to 22 328)
 NU only44 93337 68547 775<.001−9826 (−13 956 to −5695)
 1 endoscopy + NU60 32455 20361 683<.001−6849 (−10 359 to −3339)
 2 endoscopies + NU76 18680 21974 293.472928 (−4868 to 10 723)
Total 180-day costs
 1 endoscopy56 47055 43358 300.20−12 853 (−30 849 to 5142)
 2 endoscopies85 09385 09385 674.49−8206 (−33 909 to 17 497)
 NU only58 72941 78663 747<.001−20 344 (−26 746 to −13 941)
 1 endoscopy + NU76 61566 86680 029<.001−14 385 (−18 982 to− 9788)
 2 endoscopies + NU97 91897 64498 295.52−3271 (−13 238 to 6697)
Total 365-day costs
 1 endoscopy72 46369 41677 929.21−15 196 (−38 022 to 7630)
 2 endoscopies104 50898 090111 096.55−8600 (−41 096 to 23 897)
 NU only81 78760 93489 613<.001−27 879 (−37 644 to −18 114)
 1 endoscopy + NU103 77083 847111 880<.001−26 491 (−33 090 to −19 892)
 2 endoscopies + NU126 895119 294131 067.13−10 682 (−24 444 to 3081)
CostsTotal cohort, $Low risk, $High risk, $PaHigh-low estimate (95% CI), $b
Total 90-day costs
 1 endoscopy49 86249 12649 862.42−5302 (−18 440 to 7837)
 2 endoscopies70 76771 34366 821.952105 (−18 117 to 22 328)
 NU only44 93337 68547 775<.001−9826 (−13 956 to −5695)
 1 endoscopy + NU60 32455 20361 683<.001−6849 (−10 359 to −3339)
 2 endoscopies + NU76 18680 21974 293.472928 (−4868 to 10 723)
Total 180-day costs
 1 endoscopy56 47055 43358 300.20−12 853 (−30 849 to 5142)
 2 endoscopies85 09385 09385 674.49−8206 (−33 909 to 17 497)
 NU only58 72941 78663 747<.001−20 344 (−26 746 to −13 941)
 1 endoscopy + NU76 61566 86680 029<.001−14 385 (−18 982 to− 9788)
 2 endoscopies + NU97 91897 64498 295.52−3271 (−13 238 to 6697)
Total 365-day costs
 1 endoscopy72 46369 41677 929.21−15 196 (−38 022 to 7630)
 2 endoscopies104 50898 090111 096.55−8600 (−41 096 to 23 897)
 NU only81 78760 93489 613<.001−27 879 (−37 644 to −18 114)
 1 endoscopy + NU103 77083 847111 880<.001−26 491 (−33 090 to −19 892)
 2 endoscopies + NU126 895119 294131 067.13−10 682 (−24 444 to 3081)
a

P values calculated with a 2-sample Wilcoxon test to evaluate the difference between groups. All statistical tests were 2-sided. CI = confidence interval; NU = nephroureterectomy.

b

Difference between low- and high-risk groups (high-low estimate, 95% CI) in 2020 US dollars.

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