Table 4 Open in new tab Performance of...

Table 4

Performance of BVLSTM-MHC along with ten existent MHC class I predictors on independent MHCBN dataset

Methods	ACC	AUC	F1	MCC	Specificity	Sensitivity	Precision	AUPR	# Postive examples	# Negative examples
ANN [44]	0.8827	0.9166	0.6866	0.6205	0.9507	0.6216	0.7667	0.7726	37	142
comblibsidney 2008 [71]	0.7419	0.1141	—	0.0000	1.0000	0.0000	0.0000	0.1591	16	46
NetMHCcons [42]	0.8883	0.9169	0.7222	0.6528	0.9366	0.7027	0.7429	0.8457	37	142
NetMHCpan [63]	0.8547	0.9024	0.5938	0.5173	0.9437	0.5135	0.7037	0.7471	37	142
NetMHCpan EL [43]	0.8156	0.8258	0.5075	0.3989	0.9085	0.4595	0.5667	0.5977	37	142
PickPocket [27]	0.8715	0.8429	0.6849	0.6043	0.9225	0.6757	0.6944	0.6378	37	142
SMM [72]	0.9268	0.9508	0.7692	0.7266	0.9635	0.7407	0.8000	0.8548	27	137
SMMPMBEC [25]	0.9146	0.9586	0.7308	0.6808	0.9562	0.7037	0.7600	0.8581	27	137
BVLSTM-MHC	0.9548	0.9512	0.8750	0.8490	0.9832	0.8333	0.9211	0.9112	42	179
CNN-NF [46]	0.8606	0.8513	0.6234	0.5449	0.8908	0.7059	0.5581	0.6383	34	174
MHCflurry [45]	0.7834	0.7526	0.4946	0.3633	0.8352	0.5610	0.4423	0.4569	41	176

Methods	ACC	AUC	F1	MCC	Specificity	Sensitivity	Precision	AUPR	# Postive examples	# Negative examples
ANN [44]	0.8827	0.9166	0.6866	0.6205	0.9507	0.6216	0.7667	0.7726	37	142
comblibsidney 2008 [71]	0.7419	0.1141	—	0.0000	1.0000	0.0000	0.0000	0.1591	16	46
NetMHCcons [42]	0.8883	0.9169	0.7222	0.6528	0.9366	0.7027	0.7429	0.8457	37	142
NetMHCpan [63]	0.8547	0.9024	0.5938	0.5173	0.9437	0.5135	0.7037	0.7471	37	142
NetMHCpan EL [43]	0.8156	0.8258	0.5075	0.3989	0.9085	0.4595	0.5667	0.5977	37	142
PickPocket [27]	0.8715	0.8429	0.6849	0.6043	0.9225	0.6757	0.6944	0.6378	37	142
SMM [72]	0.9268	0.9508	0.7692	0.7266	0.9635	0.7407	0.8000	0.8548	27	137
SMMPMBEC [25]	0.9146	0.9586	0.7308	0.6808	0.9562	0.7037	0.7600	0.8581	27	137
BVLSTM-MHC	0.9548	0.9512	0.8750	0.8490	0.9832	0.8333	0.9211	0.9112	42	179
CNN-NF [46]	0.8606	0.8513	0.6234	0.5449	0.8908	0.7059	0.5581	0.6383	34	174
MHCflurry [45]	0.7834	0.7526	0.4946	0.3633	0.8352	0.5610	0.4423	0.4569	41	176